Analyze 12 Sample Results - Flash Unipept

Colors for all plots:

library(RColorBrewer)
ns_ws_color_values <- c("dodgerblue", "darkorange2")
volcano_colors <- scale_color_manual(values = c("grey50", "seagreen3"), guide = FALSE)
ns_ws_colors <- rep(ns_ws_color_values, 11)
heatmap_colors <- brewer.pal(name = 'PuBu', n = 9)


# labels for volcano plots

1 Taxonomy

1.1 Most Abundant Taxa

tax_descript <- read.delim('mqome_outputs/tax_descript_out.tab')

tax_samp_columns <- 6:27
tax_samp_names <- names(tax_descript)[tax_samp_columns]
ns_names <- tax_samp_names[seq(1, length(tax_samp_names), by = 2)]
ws_names <-  tax_samp_names[seq(2, length(tax_samp_names), by = 2)]

not_useful <- c('root', 'Bacteria', 'Metazoa', 'Chordata', 'Sus')
# clean <- filter(tax_descript, !(taxon_name %in% not_useful)) %>%
#     melt(id.vars = "taxon_name", measure.vars = c('NS_mean', 'WS_mean'))

ns <- filter(tax_descript, !is.na(NS_mean) & !(taxon_name %in% not_useful) & rank == "genus") %>%
    arrange(-NS_mean) %>%
    head(10)
ws <- filter(tax_descript, !is.na(WS_mean) & !(taxon_name %in% not_useful) & rank == "genus") %>%
    arrange(-WS_mean) %>%
    head(10)
    
ggplot(ns) +
    geom_bar(aes(x = reorder(taxon_name, -NS_mean), y = 2^NS_mean), stat = "identity") +
    theme_bw(base_size = 16) + 
    theme(axis.text.x = element_text(angle = 45, hjust=1, vjust=1)) +
    labs(x = "Taxon", y = "Total Peptide Intensity",
         title = "Most Abundant Genera in NS")

ggplot(ws) +
    geom_bar(aes(x = reorder(taxon_name, -WS_mean), y = 2^WS_mean), stat = "identity") +
    theme_bw(base_size = 16) + 
    theme(axis.text.x = element_text(angle = 45, hjust=1, vjust=1)) +
    labs(x = "Taxon", y = "Total Peptide Intensity",
         title = "Most Abundant Genera in WS")

library(ggplot2)
plt_volcano <- function(df, fc_name = "log2fc_NS_over_WS", xlab = "Log2 Fold Change: WS over NS",
                        textcol = "id",
                        ylab = "-Log10 FDR-corrected p value"){
    df$rev_fc <- (-1) * df[, fc_name]
    df$neglog10p <- -log10(df[, "corrected_p"])
    df$id <- df[, textcol]
    xmax <- max(df$rev_fc) * 1.2
    xmin <- min(df$rev_fc) * 1.2
    ymax <- max(df$neglog10p) * 1.2
    ymin <- min(df$neglog10p) * 1.2
    ggplot(df, aes(x = rev_fc, y = neglog10p)) + 
        geom_point(aes(color = de)) + 
        geom_text(data = subset(df, de),
                  aes(label = id), check_overlap = TRUE, nudge_y = 0.1,
                  size = 3) +
        geom_vline(xintercept = -1, lty = 2, alpha = 0.7) + 
        geom_vline(xintercept = 1, lty = 2, alpha = 0.7) +
        geom_hline(yintercept = -log10(0.05), lty = 3) +
        theme_bw(base_size=16) +
        volcano_colors +
        scale_x_continuous(limits = c(xmin, xmax)) +
        scale_y_continuous(limits = c(ymin, ymax)) +
        labs(x = xlab, y = ylab)
}

tax <- read.delim('mqome_outputs/tax_test_out.tab') %>%
    mutate(de = abs(log2fc_NS_over_WS) > 1 & corrected_p < 0.05)

plt_volcano(tax, textcol = "taxon_name")

## Warning: Removed 1 rows containing missing values (geom_point).

# ggsave("plots/tax_volcano.png", dpi = 700, width = 6, height = 5, units = "in")

Differentially expressed taxa:

knitr::kable(filter(tax, de) %>%
                 arrange(log2fc_NS_over_WS) %>% select(-starts_with("Intensity"), -de)) %>%
    kable_styling()

id	taxon_name	rank	NS_mean	WS_mean	X730NS	X730WS	X733NS	X733WS	X734NS	X734WS	X737NS	X737WS	X769NS	X769WS	X781NS	X781WS	X795NS	X795WS	X852NS	X852WS	X861NS	X861WS	X866NS	X866WS	X867NS	X867WS	log2fc_NS_over_WS	p	corrected_p
1303	Streptococcus oralis	species	23.22416	26.49327	24.61913	25.41917	22.83741	23.79503	20.51185	27.75181	21.06242	25.59211	23.07133	27.39447	25.44110	26.18516	21.90207	25.40395	23.07682	25.18758	20.32113	25.43278	20.17130	27.88294	20.20873	26.15946	-3.269104	0.0000105	0.0003293
1311	Streptococcus agalactiae	species	19.40248	22.17631	19.70554	19.86672	19.87718	22.05235	NA	19.86161	18.32553	22.12985	19.76188	19.07958	18.91880	19.83587	17.19112	24.27337	20.45872	20.46395	18.68725	22.59241	NA	23.14286	NA	21.24660	-2.773829	0.0040412	0.0234264
1318	Streptococcus parasanguinis	species	27.17256	29.89048	22.25439	27.51962	29.70694	31.87113	24.13795	30.28508	22.39546	29.09170	24.01301	22.92198	20.03688	30.76752	22.07445	28.73243	25.02206	28.46672	29.02532	30.67545	NA	26.05625	22.10327	28.92452	-2.717921	0.0014056	0.0107762
1716	Corynebacterium	genus	19.49116	21.77332	NA	23.41431	21.57183	21.92202	17.40592	20.98497	18.36076	NA	19.31911	20.55097	19.99197	20.46952	19.54283	19.25825	NA	19.78233	16.78195	22.90735	15.77392	19.30510	18.51845	22.41307	-2.282158	0.0036865	0.0234264
671232	Streptococcus anginosus group	species group	20.28150	22.20879	22.35135	20.65324	20.19383	20.85442	NA	22.05461	17.14221	21.57271	19.47772	22.15229	20.92024	22.91692	19.61355	23.47932	18.61457	21.10613	19.30032	20.41985	NA	22.77606	17.69361	22.77636	-1.927288	0.0006978	0.0068764
84998	Coriobacteriia	class	22.18555	23.77074	NA	NA	NA	23.98209	21.63562	22.60577	NA	22.41337	22.14784	22.52463	22.05830	24.23408	NA	NA	22.22173	23.09212	22.63341	24.70457	NA	23.39418	22.23900	24.69697	-1.585197	0.0043164	0.0236374
1300	Streptococcaceae	family	31.11542	32.68833	32.60986	32.40582	32.88687	33.25844	29.10124	32.24974	29.50735	31.89915	30.99645	32.18628	30.45779	33.34245	29.29589	33.14250	29.79444	32.60872	31.53910	32.73683	25.84802	32.48955	30.34748	32.49589	-1.572907	0.0006705	0.0068764
1301	Streptococcus	genus	31.08971	32.65184	32.59463	32.37682	32.85508	33.21734	29.05996	32.21993	29.48224	31.86753	30.97660	32.16226	30.43200	33.29487	29.27092	33.09630	29.77171	32.59319	31.50170	32.68661	25.75887	32.45361	30.33051	32.46894	-1.562131	0.0007204	0.0068764
186826	Lactobacillales	order	31.70213	32.83255	33.07344	32.51934	33.31981	33.33631	29.89601	32.41815	29.79746	32.07213	31.20515	32.30221	31.22706	33.44939	29.95189	33.21137	31.06755	32.81533	32.11868	32.83792	30.44890	32.80914	31.11889	32.73507	-1.130421	0.0006238	0.0068764
91061	Bacilli	class	31.82475	32.87478	33.19818	32.53635	33.47169	33.41777	29.98305	32.48714	29.95973	32.09665	31.26083	32.33574	31.25938	33.47173	30.06101	33.24753	31.18587	32.85649	32.23201	32.89106	30.72320	32.85009	31.18726	32.76584	-1.050028	0.0009908	0.0081384
714	Aggregatibacter actinomycetemcomitans	species	21.80593	19.40787	18.69898	19.26847	NA	NA	NA	18.96109	21.57996	19.74941	NA	18.75352	21.19421	16.37818	20.41492	NA	20.65389	19.27229	23.34030	NA	22.32277	NA	22.08782	20.68479	2.398059	0.0067887	0.0329657
543	Enterobacteriaceae	family	24.62716	21.87513	21.19265	NA	24.40680	23.28443	23.56536	18.64743	22.52172	21.74932	23.19916	NA	21.86009	21.40691	22.45005	18.22018	27.46552	23.23134	23.87498	20.72540	23.60030	18.76774	23.15944	22.35185	2.752031	0.0068798	0.0329657
91347	Enterobacterales	order	25.77124	22.61820	22.53535	19.89983	24.48154	23.75350	24.18118	20.50359	22.96372	21.80704	23.60251	21.96003	22.61288	21.73108	22.58631	18.81157	28.89480	24.91971	24.31414	21.28561	23.99092	19.10895	23.41054	22.86928	3.153040	0.0053397	0.0279119
28216	Betaproteobacteria	class	28.22229	24.99892	26.70831	23.20254	22.72383	25.10784	25.47467	25.97372	29.42208	24.48036	27.91540	24.32607	26.20337	23.30315	26.25741	24.78078	30.60991	24.56892	28.33536	25.00260	27.25375	23.84324	23.74780	26.57470	3.223360	0.0110998	0.0490951
1224	Proteobacteria	phylum	31.83079	28.14518	29.67094	27.07663	26.52477	27.24211	31.84876	27.00255	30.97822	28.01059	32.55942	26.87341	30.70097	26.06894	31.36234	26.30743	31.85497	28.45389	32.94591	26.22719	32.74240	26.49805	32.19104	30.69879	3.685615	0.0000142	0.0003293
1236	Gammaproteobacteria	class	31.55564	27.58421	29.33425	25.19883	25.58780	25.55395	31.71497	24.90618	30.12998	27.64196	32.41164	26.15918	30.37658	24.53079	31.22516	25.03187	29.90109	26.83219	32.78747	24.40854	32.64039	25.67636	32.08805	30.53514	3.971423	0.0000143	0.0003293
724	Haemophilus	genus	30.57273	26.45517	28.15635	19.09778	19.80104	22.69900	30.69629	NA	28.37773	26.09013	31.58786	20.51795	27.38966	NA	30.41370	NA	18.25389	20.76345	31.86647	19.27328	31.88630	20.07316	31.19575	29.28073	4.117558	0.0093552	0.0430338
712	Pasteurellaceae	family	31.38406	27.01710	29.18650	24.17558	20.48158	23.24530	31.58339	21.69881	29.96654	27.07214	32.27989	22.35234	30.13365	20.78539	31.11231	20.46058	21.45817	22.62062	32.65784	20.19822	32.52950	20.14779	31.98672	30.27939	4.366962	0.0007773	0.0068764
860	Fusobacterium periodonticum	species	30.99668	26.57806	NA	20.77388	NA	NA	31.44662	18.40673	30.12281	NA	31.56812	21.34048	31.20533	19.02315	31.43565	18.05110	28.75515	29.71273	25.72097	21.45800	30.57477	20.30901	32.07214	23.51499	4.418624	0.0000064	0.0003293
481	Neisseriaceae	family	28.13391	23.51279	26.27962	21.38035	20.26501	23.91011	25.25319	23.33600	29.37660	24.11871	27.84869	23.95588	26.05397	22.20615	26.13696	24.21883	30.53641	21.76511	28.26090	24.25663	27.11878	23.40843	23.31084	23.09876	4.621122	0.0024037	0.0172768
851	Fusobacterium nucleatum	species	27.56385	22.88842	20.19201	NA	NA	NA	27.17985	NA	29.80657	17.83374	27.68197	NA	28.35360	16.36835	25.84465	19.08040	25.35496	25.15414	20.55843	NA	26.95621	NA	26.55401	19.22058	4.675430	0.0032662	0.0220951
203491	Fusobacteriales	order	33.27793	28.40539	24.95377	23.39474	22.15873	22.44004	33.59080	23.88807	34.43152	23.85733	33.70026	22.99526	34.02278	23.57749	33.47461	23.94891	32.28573	31.81913	28.51173	22.38821	33.39903	22.38964	34.07753	24.65547	4.872536	0.0001101	0.0018087
848	Fusobacterium	genus	33.15568	28.25050	24.82397	22.22303	18.75737	21.83777	33.49153	21.17156	34.33054	21.76843	33.59801	22.70295	33.82260	22.13646	33.37215	21.61021	32.16246	31.68701	28.41431	21.69079	33.24879	21.03305	33.97311	24.29693	4.905184	0.0001977	0.0028415
467210	Lachnoanaerobaculum saburreum	species	26.09812	17.79822	NA	NA	NA	16.96795	25.02542	16.89035	25.02737	NA	23.69007	14.19746	27.54251	14.98503	27.72182	18.18870	21.06013	NA	NA	NA	NA	19.65394	20.86212	17.38265	8.299901	0.0000634	0.0012155

1.2 Principal Components Analysis

The following functions are used in both PCA and heatmap analysis:

cor.dist <- function(x){
    as.dist(1-cor(t(x)))
}
hclust.ward <- function(x) {
    hclust(x,method="ward.D")
}
impute <- function(mat) {
    mat[mat == 0] <- NA
    mat[is.na(mat)] <- min(mat, na.rm = TRUE) * 1e-3
    mat
}

pad <- function(data, multiple){
    mind <- min(data)
    maxd <- max(data)
    if (mind >= 0){
        pmind <- mind - mind * (multiple - 1)
    } else {
        pmind <- mind + mind * (multiple - 1)
    }
    if (maxd >= 0){
        pmaxd <- maxd * multiple
    } else {
        pmaxd <- maxd - maxd * (multiple - 1)
    }
    c(pmind, pmaxd)
}

plt_principal_components <- function(df, samp_columns, cols){
    mat <- impute(data.matrix(df[, samp_columns]))
    pr <- prcomp(mat, scale=TRUE, center=TRUE)
    xpadding <- 1.1
    ypadding <- 1.3
    plot(pr$rotation,
         xlab = paste("PCA1 (",
                  format(summary(pr)$importance[2, 1]*100, digits = 3), "%)",
                  sep = ""),
         ylab = paste("PCA2 (",
                  format(summary(pr)$importance[2, 2]*100, digits = 3), "%)",
                  sep = ""),
         col = cols, pch = 20,
         xlim = pad(pr$rotation[, 1], xpadding),
         ylim = pad(pr$rotation[, 2], ypadding),
         cex = 1.5)
    text(pr$rotation,
        labels = str_remove(colnames(mat), 'X'),
        col = cols,
        pos = 3,
        cex = 1)
    grid()
}

plt_heatmap <- function(df, samp_columns, cols, heatmap_colors = brewer.pal(name = 'PuBu', n = 9)){
    # impute
    mat <- impute(data.matrix(df[, samp_columns]))
    
    # scale rows
    datmat.scale <- t(apply(mat, 1, scale))
    rownames(datmat.scale) <- df$id
    colnames(datmat.scale) <- str_replace(colnames(df[, samp_columns]), "Intensity\\.(.*)", "\\1")
    par(mar = rep(5, 4))
    feature.dend <- as.dendrogram(hclust.ward(cor.dist(datmat.scale)))
    sample.dend <- as.dendrogram(hclust.ward(cor.dist(t(datmat.scale))))
    heatmap.2(datmat.scale,
              Colv = sample.dend,
              Rowv = feature.dend,
              distfun = cor.dist,
              hclustfun = hclust.ward,
              trace="none",
              col = heatmap_colors,
              margins = c(10, 10),
              cexRow = 0.3,
              ColSideColors = ns_ws_colors,
              density.info = "none")
}

tax_descript <- read.delim('mqome_outputs/tax_descript_out.tab')
# ge3 <- (rowSums(!is.na(tax_descript[, ns_names])) >= 3) & (rowSums(!is.na(tax_descript[, ws_names])) >= 3)
# tax_descript <- tax_descript[ge3, ]

# principal components, tax
plt_principal_components(tax_descript, tax_samp_columns, ns_ws_colors)

1.3 Heatmap

# heatmap, tax
plt_heatmap(tax_descript, tax_samp_columns, ns_ws_cols)

2 Function - GO

2.1 Volcano

func <- read.delim('mqome_outputs/func_full_test_out.tab') %>%
    mutate(de = abs(log2fc_NS_over_WS) > 1 & corrected_p < 0.05)
fc <- "log2fc_NS_over_WS"
p <- "corrected_p"
plt_volcano(func)

## Warning: Removed 1 rows containing missing values (geom_point).

# ggsave("plots/func_full_volcano.png",dpi = 700, width = 10, height = 8, units = "in")

2.1.1 Differentially expressed GO terms

knitr::kable(filter(func, de) %>%
                 arrange(log2fc_NS_over_WS) %>% select(-starts_with("Intensity"), -de)) %>%
    kable_styling()

id	name	namespace	NS_mean	WS_mean	X730NS	X730WS	X733NS	X733WS	X734NS	X734WS	X737NS	X737WS	X769NS	X769WS	X781NS	X781WS	X795NS	X795WS	X852NS	X852WS	X861NS	X861WS	X866NS	X866WS	X867NS	X867WS	log2fc_NS_over_WS	p	corrected_p
GO:0009758	carbohydrate utilization	biological_process	19.64071	25.19454	20.22752	23.49159	17.87051	24.95427	NA	20.03198	15.97024	21.02572	NA	NA	21.67277	26.36220	18.58554	26.79697	NA	NA	18.36765	24.22839	19.69168	26.10412	16.39616	21.71047	-5.553831	0.0002075	0.0011327
GO:0050053	levansucrase activity	molecular_function	19.64071	25.19454	20.22752	23.49159	17.87051	24.95427	NA	20.03198	15.97024	21.02572	NA	NA	21.67277	26.36220	18.58554	26.79697	NA	NA	18.36765	24.22839	19.69168	26.10412	16.39616	21.71047	-5.553831	0.0002075	0.0011327
GO:0047112	pyruvate oxidase activity	molecular_function	21.90398	26.69461	22.28475	26.28637	22.68580	27.88882	22.38514	26.13205	20.29239	25.77884	20.58803	27.66222	22.86691	26.64936	20.82884	24.74007	21.62596	24.73793	21.47099	26.70217	22.27132	27.32108	21.10449	26.30199	-4.790637	0.0000000	0.0000002
GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor	molecular_function	21.92015	26.69601	22.41069	26.28637	22.68580	27.88882	22.38514	26.13205	20.29239	25.77884	20.60688	27.67004	22.86691	26.64936	20.82884	24.74007	21.62596	24.73793	21.47099	26.70217	22.27132	27.32108	21.10449	26.30199	-4.775852	0.0000000	0.0000002
GO:0051992	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity	molecular_function	20.11010	24.27361	19.25454	22.19205	18.37598	22.93504	21.17313	25.31514	18.42382	25.30963	19.10782	23.04018	21.00790	24.55218	21.19182	24.35261	19.70047	24.22632	19.91851	23.22848	19.75533	24.33540	19.88795	24.36947	-4.163513	0.0000000	0.0000015
GO:0009611	response to wounding	biological_process	21.99280	26.13936	20.36087	23.46226	21.61677	27.00670	NA	19.85102	20.52282	24.83025	NA	NA	24.25786	26.55974	21.80788	27.32969	19.57268	26.05027	19.68477	24.13049	22.15628	27.28926	20.48058	25.34118	-4.146561	0.0003334	0.0015953
GO:0004867	serine-type endopeptidase inhibitor activity	molecular_function	21.96959	26.10753	20.29277	23.37772	21.58100	26.99672	NA	19.72696	20.51815	24.77203	NA	NA	24.17814	26.55095	21.80788	27.29301	20.74105	25.96607	19.55960	24.11865	22.09167	27.27269	20.40639	25.25425	-4.137941	0.0004185	0.0018678
GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	molecular_function	19.46860	23.48235	17.15524	21.90607	18.28245	23.08441	15.77739	21.33515	17.49090	23.00548	15.50545	20.67675	20.15705	25.26184	16.63559	25.06116	15.56945	21.18496	22.40752	23.15161	17.97292	23.53818	16.43305	22.00878	-4.013755	0.0000019	0.0000678
GO:0043418	homocysteine catabolic process	biological_process	20.77314	24.68613	22.30827	24.38390	20.44343	23.10570	19.82547	25.21507	17.97800	24.74367	19.13942	23.83767	22.06358	24.62156	19.93143	24.38502	21.38788	25.11273	18.96940	23.78442	20.74369	25.92821	19.82937	24.36984	-3.912987	0.0000000	0.0000028
GO:0050040	lactate 2-monooxygenase activity	molecular_function	21.05537	24.89088	22.15955	23.68308	19.06003	23.16936	21.50115	24.86412	17.46528	22.55559	20.05000	26.49857	22.78111	23.27137	20.39437	22.43461	19.00065	21.42395	21.02585	25.22976	21.01116	26.71031	20.12854	24.25636	-3.835507	0.0000397	0.0004607
GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	molecular_function	19.43045	23.10007	17.15524	21.89454	17.95180	22.51290	15.77739	21.26524	17.47652	22.94410	15.50545	20.67675	19.98368	24.83118	16.63559	24.44340	15.56945	21.18496	22.40752	22.91481	17.92321	23.31518	16.43305	21.68037	-3.669613	0.0000017	0.0000608
GO:0015444	magnesium-importing ATPase activity	molecular_function	18.00830	21.67227	18.18779	20.58478	19.03612	23.86186	15.73561	20.07739	17.92523	19.60892	17.83180	22.15224	18.95505	22.64435	NA	20.07563	NA	19.49760	18.71424	20.30669	15.31551	21.48599	14.35227	19.50024	-3.663973	0.0000980	0.0007031
GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	molecular_function	18.93659	22.57366	18.40822	21.59288	19.27821	22.62349	NA	22.89709	16.19291	22.74186	18.92646	22.40184	20.17211	23.47222	18.92478	21.75136	18.03123	22.53872	18.46160	22.27998	19.07335	22.81959	19.19704	22.22989	-3.637073	0.0000000	0.0000007
GO:0001540	amyloid-beta binding	molecular_function	18.73932	22.29467	19.94373	21.59515	18.65066	21.63874	18.32439	21.38616	19.86203	21.16143	14.28788	22.33851	17.35438	23.18915	17.92578	22.38669	19.02023	21.31882	16.52278	21.55248	19.38555	24.12054	18.47883	19.59341	-3.555340	0.0000065	0.0001492
GO:0019120	hydrolase activity, acting on acid halide bonds, in C-halide compounds	molecular_function	17.31300	20.86577	17.01515	NA	NA	NA	16.00171	19.55628	NA	NA	NA	19.61650	18.76693	21.72273	16.49914	21.89353	NA	NA	NA	18.32867	16.23950	21.07179	NA	NA	-3.552769	0.0016351	0.0054199
GO:0005833	hemoglobin complex	cellular_component	17.32033	20.86562	NA	21.06401	17.69188	19.49988	NA	20.54596	16.04613	NA	16.83219	20.85434	16.47280	20.84597	17.48299	21.08867	18.24994	21.46723	NA	NA	NA	NA	NA	NA	-3.545292	0.0000020	0.0000683
GO:0003852	2-isopropylmalate synthase activity	molecular_function	20.53451	24.07392	21.66310	22.72808	18.79670	22.86310	18.35115	20.96715	18.54027	23.05431	20.78534	22.24505	20.66917	25.49617	19.57699	25.97102	20.56342	22.10658	19.97916	22.64975	22.17944	24.92095	19.25470	22.92807	-3.539411	0.0000283	0.0003940
GO:0043896	glucan 1,6-alpha-glucosidase activity	molecular_function	19.00483	22.47330	17.19596	19.90977	20.85816	23.76092	19.90699	22.62005	14.45938	21.53302	14.53895	22.96535	18.79449	22.01480	17.93288	20.38384	18.62086	20.87249	19.91272	21.28296	18.95693	24.17492	16.64158	21.04552	-3.468471	0.0000517	0.0005092
GO:0055088	lipid homeostasis	biological_process	15.45476	18.90854	15.89148	18.49781	16.84043	19.09709	NA	18.16237	NA	NA	15.46407	18.77323	15.38585	18.84910	14.18354	18.49909	13.85112	18.80946	NA	NA	13.85691	19.87593	NA	NA	-3.453776	0.0000013	0.0000586
GO:0036267	invasive filamentous growth	biological_process	21.65653	25.10824	NA	23.14658	22.92068	24.90564	19.81181	23.72086	21.90963	25.11369	NA	NA	22.00821	26.28373	20.44186	26.24467	21.33497	23.31709	22.29045	25.13268	19.70091	24.64306	21.35474	25.10933	-3.451709	0.0000030	0.0000906
GO:0019676	ammonia assimilation cycle	biological_process	21.67321	24.98959	NA	22.91939	22.92068	24.68917	19.26323	23.72041	21.90732	25.00557	NA	NA	21.96916	26.05606	20.83005	26.24456	21.62315	23.32713	22.29045	25.01181	19.26427	24.45483	21.32976	25.01985	-3.316379	0.0000089	0.0001829
GO:0015418	quaternary-ammonium-compound-transporting ATPase activity	molecular_function	18.49486	21.75537	19.98016	22.75854	NA	19.31527	17.68762	22.70613	17.22060	20.86161	18.37144	23.23678	18.48134	19.18322	18.94662	20.89082	17.94175	22.05878	15.27258	19.53249	NA	NA	18.69679	20.36840	-3.260510	0.0002455	0.0012760
GO:0008886	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity	molecular_function	22.65198	25.77510	20.35696	24.20154	25.41481	25.78109	19.51755	23.70870	19.48467	24.87343	19.52121	23.87613	21.93470	27.37467	20.22219	27.10242	20.19148	23.30084	23.02294	25.11373	22.99108	26.79378	19.77326	23.71338	-3.123117	0.0000316	0.0004042
GO:0008900	potassium:proton exchanging ATPase activity	molecular_function	19.18834	22.29318	20.06389	22.53043	20.20933	22.79529	17.29636	21.81143	16.67913	20.57370	19.94118	23.22741	19.29179	23.06859	17.94784	20.81396	20.07583	22.06431	19.51352	21.97709	16.27215	22.01539	17.31504	22.17688	-3.104840	0.0000016	0.0000599
GO:0004638	phosphoribosylaminoimidazole carboxylase activity	molecular_function	17.28528	20.36165	16.49469	20.41248	17.47828	17.99792	16.67451	20.38583	NA	20.48688	17.86881	20.65396	17.45572	21.16213	NA	19.83874	NA	NA	NA	NA	NA	NA	NA	NA	-3.076367	0.0001836	0.0010482
GO:0016856	racemase and epimerase activity, acting on hydroxy acids and derivatives	molecular_function	20.17107	23.20117	NA	NA	22.43809	21.45314	20.40523	24.03870	15.39704	23.02003	NA	NA	18.13452	24.50154	18.82519	21.37828	18.42790	NA	NA	NA	NA	NA	15.45613	21.40383	-3.030093	0.0042133	0.0119414
GO:0050118	N-acetyldiaminopimelate deacetylase activity	molecular_function	18.19646	21.20364	19.76393	20.61372	18.85140	20.41972	16.59964	20.99470	18.10545	20.37606	18.46717	22.80383	18.41107	22.22957	NA	20.74353	17.52502	18.72905	14.06826	19.75216	17.92331	21.90256	16.51976	19.73884	-3.007174	0.0000572	0.0005399
GO:0050043	lactate racemase activity	molecular_function	20.20593	23.19248	NA	NA	22.37971	21.26720	20.40523	24.03870	15.39704	23.02003	NA	NA	18.13452	24.50154	15.10042	21.37828	NA	NA	NA	NA	NA	NA	15.45613	21.40383	-2.986554	0.0059716	0.0159283
GO:0004531	deoxyribonuclease II activity	molecular_function	17.72374	20.69418	18.28809	20.90847	NA	NA	16.66177	21.33660	17.45631	21.40998	14.15286	19.62402	18.88843	20.95717	18.20055	21.12087	NA	20.80321	15.14209	18.20613	18.13171	19.21790	NA	NA	-2.970437	0.0002325	0.0012296
GO:0019218	regulation of steroid metabolic process	biological_process	19.89516	22.84850	20.29506	21.81603	20.23563	23.04673	17.88995	22.57614	21.44699	22.74640	15.87284	20.73327	16.26559	22.92470	18.58845	23.87321	20.60519	22.90378	16.46741	20.37697	20.97052	24.32963	19.66206	20.97850	-2.953343	0.0001127	0.0007546
GO:0032350	regulation of hormone metabolic process	biological_process	19.89516	22.84850	20.29506	21.81603	20.23563	23.04673	17.88995	22.57614	21.44699	22.74640	15.87284	20.73327	16.26559	22.92470	18.58845	23.87321	20.60519	22.90378	16.46741	20.37697	20.97052	24.32963	19.66206	20.97850	-2.953343	0.0001127	0.0007546
GO:0045834	positive regulation of lipid metabolic process	biological_process	19.31019	22.26354	19.71010	21.23107	19.65066	22.46177	17.30499	21.99118	20.86203	22.16143	15.28788	20.14831	15.68063	22.33974	18.00349	23.28824	20.02023	22.31882	15.88245	19.79201	20.38555	23.74466	19.07709	20.39354	-2.953343	0.0001127	0.0007546
GO:0046885	regulation of hormone biosynthetic process	biological_process	19.31019	22.26354	19.71010	21.23107	19.65066	22.46177	17.30499	21.99118	20.86203	22.16143	15.28788	20.14831	15.68063	22.33974	18.00349	23.28824	20.02023	22.31882	15.88245	19.79201	20.38555	23.74466	19.07709	20.39354	-2.953343	0.0001127	0.0007546
GO:0050810	regulation of steroid biosynthetic process	biological_process	19.31019	22.26354	19.71010	21.23107	19.65066	22.46177	17.30499	21.99118	20.86203	22.16143	15.28788	20.14831	15.68063	22.33974	18.00349	23.28824	20.02023	22.31882	15.88245	19.79201	20.38555	23.74466	19.07709	20.39354	-2.953343	0.0001127	0.0007546
GO:0042245	RNA repair	biological_process	18.20462	21.15704	18.94503	21.31819	17.81755	20.67622	18.84146	20.48570	15.18754	20.33652	18.64826	22.28229	17.71310	21.47068	18.84628	20.52101	17.62827	20.47937	17.34933	19.65779	18.73711	22.49641	17.43099	19.81346	-2.952418	0.0000013	0.0000586
GO:0008866	fructuronate reductase activity	molecular_function	22.07955	25.02319	14.82660	23.58079	24.93744	24.26479	22.33383	26.32726	18.09747	25.33991	NA	NA	20.29473	26.96507	17.38483	23.48957	NA	21.11180	13.70011	20.01048	16.29643	22.18473	19.22085	24.87345	-2.943638	0.0011939	0.0041551
GO:0052928	CTP:3’-cytidine-tRNA cytidylyltransferase activity	molecular_function	17.84691	20.78133	18.46023	20.86834	17.74881	20.29423	18.62059	19.57455	15.18754	20.25484	18.44340	21.98648	17.65560	21.37119	17.58665	20.18830	16.62631	19.73095	17.34933	19.65779	18.65579	21.97382	17.00014	19.44488	-2.934422	0.0000011	0.0000543
GO:0052929	ATP:3’-cytidine-cytidine-tRNA adenylyltransferase activity	molecular_function	17.84691	20.77609	18.46023	20.81309	17.74881	20.29423	18.62059	19.57455	15.18754	20.25484	18.44340	21.98648	17.65560	21.37119	17.58665	20.18830	16.62631	19.73095	17.34933	19.65779	18.65579	21.97382	17.00014	19.44488	-2.929179	0.0000011	0.0000543
GO:0042586	peptide deformylase activity	molecular_function	21.95548	24.78234	23.22837	25.53440	21.61387	23.75688	20.91211	25.50453	21.03872	24.83184	20.78958	24.92632	22.15499	24.84515	20.94254	24.77445	23.57824	25.31451	20.31664	23.61693	21.09821	24.60259	21.51560	22.60571	-2.826867	0.0000005	0.0000347
GO:2000184	positive regulation of progesterone biosynthetic process	biological_process	18.57673	21.37720	18.71010	20.23107	18.65066	21.46177	16.30499	20.99118	19.86203	21.16143	14.28788	19.14831	NA	21.33974	17.00349	22.28824	19.02023	21.31882	NA	NA	19.38555	22.74466	18.07709	19.39354	-2.800464	0.0002722	0.0013898
GO:0052927	CTP:tRNA cytidylyltransferase activity	molecular_function	17.28578	20.07522	17.50877	19.18890	NA	NA	NA	18.46998	NA	18.96681	18.34141	21.45039	17.49082	20.60036	16.25737	18.63548	16.46615	19.38707	NA	NA	NA	21.33860	16.40919	18.03765	-2.789441	0.0009819	0.0035491
GO:0004354	glutamate dehydrogenase (NADP+) activity	molecular_function	24.55020	27.33936	25.57195	26.85861	25.89499	26.97159	23.19113	26.68990	23.71569	27.01126	24.08121	27.01888	25.22015	27.87696	23.17976	27.63915	24.54915	27.37488	24.27781	27.61372	22.17476	27.82841	24.15210	27.27011	-2.789166	0.0000000	0.0000042
GO:1901214	regulation of neuron death	biological_process	17.96212	20.73308	18.20315	20.67549	NA	NA	16.66177	21.06039	17.45631	21.40998	NA	NA	18.81013	20.67737	18.14828	20.79452	NA	20.80321	NA	NA	17.58528	17.79334	NA	NA	-2.770960	0.0006897	0.0027010
GO:0004455	ketol-acid reductoisomerase activity	molecular_function	24.26959	27.03987	24.66741	26.07641	24.76394	27.01790	23.26106	26.31506	23.69507	26.95297	24.04802	26.09434	24.56272	27.81590	24.19224	28.24056	24.12677	26.34926	24.62403	27.01040	24.18428	27.05071	24.19205	26.75115	-2.770286	0.0000000	0.0000004
GO:0070476	rRNA (guanine-N7)-methylation	biological_process	18.18686	20.95119	NA	19.55116	17.44409	19.66541	18.77157	20.14243	16.32456	20.16609	17.71818	21.08359	18.73480	20.59114	18.22839	18.61920	18.70757	22.83966	18.28717	20.58310	15.00790	21.87047	19.03221	20.25562	-2.764333	0.0000734	0.0006062
GO:0010285	L,L-diaminopimelate aminotransferase activity	molecular_function	17.79323	20.55750	NA	NA	NA	NA	NA	20.48531	16.15884	20.88783	NA	NA	17.48560	21.19087	18.84992	20.86963	NA	NA	NA	19.29806	16.91446	17.19821	18.11048	21.12665	-2.764268	0.0060360	0.0160526
GO:0005796	Golgi lumen	cellular_component	18.82928	21.59164	18.84491	20.68213	18.65066	21.46177	16.30499	21.17013	19.88601	21.30942	15.29001	19.57956	NA	21.39314	17.09696	22.53271	19.16334	21.86266	NA	NA	20.21348	22.92554	18.07709	19.39354	-2.762361	0.0001782	0.0010221
GO:0047482	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity	molecular_function	19.83594	22.56550	21.22293	23.23686	21.24938	22.15425	19.16046	21.45484	14.48984	20.12190	18.85722	22.62629	20.68204	23.37368	18.76941	22.24830	20.01562	22.73709	18.36409	21.70996	18.35037	23.65543	18.64315	21.83885	-2.729562	0.0000683	0.0005850
GO:0001680	tRNA 3’-terminal CCA addition	biological_process	18.37338	21.10010	18.54314	21.12720	17.81755	20.67622	19.02265	20.36409	15.18754	20.25484	18.64826	22.26159	18.14936	21.51955	18.62460	20.45815	19.32124	20.08335	17.34933	19.65779	18.73711	22.49641	17.51824	19.66160	-2.726717	0.0000076	0.0001627
GO:1903494	response to dehydroepiandrosterone	biological_process	19.05333	21.76176	18.96605	20.81817	18.65066	21.46177	16.48494	21.43006	20.03375	21.35962	16.17616	20.17419	18.87900	21.60804	17.89513	22.65812	19.47768	22.01484	NA	NA	20.54847	23.15334	18.13569	19.49641	-2.708426	0.0000671	0.0005807
GO:1903496	response to 11-deoxycorticosterone	biological_process	19.05333	21.76176	18.96605	20.81817	18.65066	21.46177	16.48494	21.43006	20.03375	21.35962	16.17616	20.17419	18.87900	21.60804	17.89513	22.65812	19.47768	22.01484	NA	NA	20.54847	23.15334	18.13569	19.49641	-2.708426	0.0000671	0.0005807
GO:0034227	tRNA thio-modification	biological_process	21.61208	24.30533	22.11108	24.10780	22.26530	24.66100	20.58914	24.43373	20.83663	23.83631	21.03045	24.21873	21.96115	24.81626	20.49977	24.08343	22.83656	24.55175	21.25728	23.80037	21.15289	24.95835	21.07094	22.77110	-2.693240	0.0000000	0.0000022
GO:0019290	siderophore biosynthetic process	biological_process	22.49787	25.17343	22.53293	24.97768	NA	25.02528	20.52512	23.63102	NA	NA	NA	NA	20.22081	25.33400	18.71991	25.74461	23.32128	25.34787	24.25408	25.16224	22.21973	25.73206	21.40586	24.62558	-2.675558	0.0000823	0.0006390
GO:0005788	endoplasmic reticulum lumen	cellular_component	22.83158	25.48646	24.16147	25.37945	23.17486	24.07823	21.76166	26.57153	22.46514	22.50709	20.00062	24.52636	20.29639	24.96662	23.32538	26.78509	23.93790	25.44304	21.95390	25.95512	21.01413	21.59875	23.16887	25.92296	-2.654881	0.0007412	0.0028216
GO:0004105	choline-phosphate cytidylyltransferase activity	molecular_function	19.77987	22.41915	20.99104	22.07262	18.53816	20.11879	18.26323	23.50894	19.95891	22.50815	18.27231	22.46174	20.96516	21.98898	19.50712	21.94007	18.46778	22.10130	20.18878	20.58817	20.39829	23.96407	15.74654	20.80923	-2.639279	0.0001135	0.0007546
GO:0004564	beta-fructofuranosidase activity	molecular_function	21.76043	24.39251	22.76358	22.97198	20.58579	23.32749	18.68690	22.76318	20.82641	22.71818	22.00624	23.44175	23.22205	25.43572	20.31214	26.32983	19.58148	22.62017	19.98029	22.47750	20.11748	25.58397	23.23129	22.46064	-2.632081	0.0005106	0.0021618
GO:0002143	tRNA wobble position uridine thiolation	biological_process	20.76230	23.39416	20.52763	23.04275	21.26828	23.83628	19.76999	23.87695	19.69787	23.07363	20.00538	22.93843	20.63721	23.20348	20.34697	23.42095	22.43884	23.93681	20.76805	23.02055	19.72447	23.94528	20.44582	21.84449	-2.631857	0.0000000	0.0000033
GO:0000455	enzyme-directed rRNA pseudouridine synthesis	biological_process	20.29748	22.92517	21.88312	22.84230	19.70848	21.06342	18.92121	23.00402	19.04778	22.64318	20.01488	23.32465	21.43983	23.28469	19.12222	21.87274	20.18293	23.22226	20.56354	22.58653	18.58830	24.04852	19.61640	22.23523	-2.627688	0.0000007	0.0000451
GO:0098630	aggregation of unicellular organisms	biological_process	24.79828	27.42133	25.73183	25.91693	25.21271	26.36449	24.78826	27.55984	23.15091	27.39578	25.07499	27.24301	24.36868	28.25040	24.73778	27.49493	24.95055	27.22463	25.33106	27.19998	23.44627	28.06054	24.01826	27.53666	-2.623047	0.0000000	0.0000052
GO:0003862	3-isopropylmalate dehydrogenase activity	molecular_function	19.31450	21.93158	19.21545	19.27600	NA	17.49114	16.09675	20.34172	20.62356	21.90760	19.34245	19.21818	19.18182	23.38245	18.10105	23.63439	20.33072	19.79149	18.69515	20.97683	19.57437	23.06195	17.29816	20.63124	-2.617079	0.0129748	0.0297099
GO:0006914	autophagy	biological_process	19.55573	22.14121	20.60747	22.62067	NA	NA	NA	NA	17.25824	20.65072	NA	NA	17.84309	22.37619	17.53330	21.90478	20.67495	22.43298	NA	NA	NA	NA	NA	NA	-2.585481	0.0051556	0.0140552
GO:0009374	biotin binding	molecular_function	22.03092	24.61355	20.01759	NA	20.35420	18.76526	21.25511	24.85307	21.68532	25.78282	23.18441	23.51864	22.44067	24.51588	21.71663	25.09129	21.83096	22.79538	22.19823	23.71721	22.63762	23.52634	22.28781	25.91588	-2.582632	0.0073715	0.0188661
GO:0010566	regulation of ketone biosynthetic process	biological_process	18.87439	21.44198	18.71010	20.23107	19.63530	21.61997	16.30499	21.33572	19.86203	21.16143	14.28788	19.14831	19.75382	21.52040	17.00349	22.28824	19.02023	21.31882	NA	NA	19.38555	22.74466	18.07709	19.39354	-2.567590	0.0005365	0.0022467
GO:0044432	endoplasmic reticulum part	cellular_component	23.62714	26.18480	24.82569	25.99976	23.62565	24.83230	22.64233	27.20325	23.25260	24.09505	21.68877	25.15272	21.60701	26.04048	24.22077	27.39183	24.66411	26.11115	22.65510	26.59765	22.71790	23.17051	24.02618	26.62877	-2.557660	0.0001105	0.0007546
GO:0050667	homocysteine metabolic process	biological_process	22.20301	24.74421	22.46984	24.43807	21.36619	23.16989	22.50012	25.23738	23.66338	24.74367	21.28667	24.17230	23.16931	24.64682	20.02767	24.38502	22.47090	25.13684	18.96940	23.78442	22.00747	26.04133	20.76012	24.38002	-2.541202	0.0000076	0.0001627
GO:0016889	endodeoxyribonuclease activity, producing 3’-phosphomonoesters	molecular_function	18.74194	21.28046	18.83756	21.41997	17.32720	19.04435	17.45188	21.69901	17.51994	21.85264	18.04510	20.82502	19.41553	21.44749	18.50271	21.35772	17.03692	21.16206	19.29559	19.39642	20.27057	22.09903	NA	NA	-2.538516	0.0000216	0.0003340
GO:0019825	oxygen binding	molecular_function	18.31504	20.83841	NA	21.06401	17.69188	19.49988	17.21073	21.21669	19.41753	19.45558	16.83219	20.85434	16.47280	20.84597	17.48299	21.08867	19.65984	21.46723	NA	NA	NA	NA	NA	NA	-2.523377	0.0001117	0.0007546
GO:0008832	dGTPase activity	molecular_function	18.19650	20.70882	18.64832	21.20346	19.46646	19.92788	14.52226	20.35160	16.06525	20.30349	19.74349	20.84992	16.47281	19.41586	NA	NA	17.84712	21.99730	18.08815	20.45510	14.42648	19.91126	18.04994	20.85373	-2.512313	0.0000970	0.0006976
GO:0043686	co-translational protein modification	biological_process	21.20565	23.70778	22.89424	24.91917	NA	21.11780	18.91291	24.16130	20.36880	24.29464	18.28467	24.11098	20.93492	23.67735	20.21383	23.42511	23.23908	24.22019	17.92628	21.99573	18.57970	23.15666	18.81021	20.51211	-2.502130	0.0002726	0.0013898
GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity	molecular_function	18.12883	20.61722	16.66021	19.13663	19.42195	20.84726	NA	NA	NA	NA	18.04641	20.02148	15.75510	19.82295	NA	NA	18.20016	22.12520	NA	NA	NA	NA	NA	19.24517	-2.488387	0.0083896	0.0209586
GO:0008441	3’(2’),5’-bisphosphate nucleotidase activity	molecular_function	17.38034	19.86780	NA	NA	NA	NA	16.33500	19.52895	NA	NA	14.60075	20.05048	19.08614	20.00555	17.07042	18.92802	NA	NA	NA	NA	15.64846	20.40668	NA	NA	-2.487458	0.0036038	0.0104810
GO:0003984	acetolactate synthase activity	molecular_function	21.33376	23.81728	20.41766	22.42433	21.73418	23.95102	19.28937	21.32219	19.22398	22.52816	23.00465	23.14821	21.57928	25.60541	21.12027	24.69344	20.19332	22.40972	21.83704	22.73799	21.21410	24.62979	20.71784	22.53430	-2.483519	0.0002056	0.0011288
GO:0033993	response to lipid	biological_process	20.17833	22.64517	19.96605	21.81817	19.65066	22.46177	17.48494	22.44714	21.03375	22.35962	17.17616	21.17419	19.87900	22.60804	18.89513	23.65812	20.47768	23.01484	15.88245	19.79201	22.30399	24.15825	19.13569	20.49641	-2.466840	0.0003540	0.0016561
GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	molecular_function	17.75386	20.21192	19.17525	19.49460	18.61784	20.06163	17.33528	19.76316	NA	18.71628	16.76335	21.53271	NA	NA	NA	18.12404	15.36282	18.84923	15.45128	18.21805	18.31741	22.10253	16.35334	18.57859	-2.458066	0.0024994	0.0077024
GO:0004103	choline kinase activity	molecular_function	19.47439	21.92952	20.59363	21.61277	NA	NA	18.02958	22.79577	15.79448	22.22538	16.65245	22.27776	21.67042	22.22193	18.26222	20.05245	19.75176	21.53753	14.82813	19.46218	19.23828	22.91368	16.48757	20.79538	-2.455132	0.0003493	0.0016398
GO:0047473	D-alanine [D-alanyl carrier protein] ligase activity	molecular_function	22.38917	24.83735	24.06711	24.49485	23.44589	25.43260	21.01486	25.49718	21.47789	24.33142	22.40577	24.96831	21.72198	25.32719	21.28138	24.07317	22.06927	24.88218	21.99472	24.53734	20.08725	24.45392	22.28854	24.35929	-2.448181	0.0000002	0.0000216
GO:0017057	6-phosphogluconolactonase activity	molecular_function	20.33468	22.75761	20.11041	22.39879	21.02603	21.07056	20.18294	23.51085	17.97687	21.64805	20.71110	23.55371	20.27036	24.08957	19.40446	21.04077	21.25117	22.60390	20.84598	21.45473	18.66841	23.47978	20.37268	20.74976	-2.422932	0.0001192	0.0007735
GO:0004459	L-lactate dehydrogenase activity	molecular_function	26.07235	28.47010	27.32036	27.90464	27.17693	28.69847	24.93637	28.72180	25.63255	28.42647	24.96544	27.63787	26.82746	28.86402	25.13119	28.94858	25.48706	28.49147	25.92140	28.40313	25.29675	28.36889	24.94589	28.18588	-2.397750	0.0000000	0.0000039
GO:0044406	adhesion of symbiont to host	biological_process	24.01871	26.39939	22.59951	24.17256	25.37369	25.74374	20.62694	24.88376	21.50022	25.57153	21.73480	27.07035	24.26962	26.89924	21.86868	27.44574	21.58239	23.63205	26.00941	26.56700	23.59453	25.95504	24.36739	27.51175	-2.380685	0.0002956	0.0014798
GO:0006542	glutamine biosynthetic process	biological_process	24.15820	26.53680	24.61221	25.22671	25.03113	26.63303	23.51308	26.14182	22.79876	25.94346	23.20464	26.13492	24.52855	27.48369	22.73122	26.73078	24.81347	25.34721	24.92174	26.76515	23.62179	27.49829	23.48389	26.06027	-2.378602	0.0000008	0.0000467
GO:0043628	ncRNA 3’-end processing	biological_process	18.78675	21.14541	18.54314	21.12720	18.96995	21.19027	19.54925	20.36409	15.18754	20.25484	19.72213	22.26159	18.14936	21.51955	18.70321	20.45815	19.32124	20.08335	17.34933	19.65779	18.73711	22.49641	18.72516	19.78119	-2.358653	0.0000726	0.0006031
GO:0016152	mercury (II) reductase activity	molecular_function	23.26203	25.61963	24.40390	25.18104	25.03357	26.31930	21.71014	24.80477	22.13888	25.09645	22.59010	24.88900	24.11673	26.81839	22.61148	24.02281	21.74449	26.13818	22.60199	26.21645	17.95866	23.84316	22.25756	25.48083	-2.357600	0.0001909	0.0010723
GO:0030152	bacteriocin biosynthetic process	biological_process	23.09145	25.44629	24.96161	26.03638	23.74310	24.04520	22.37240	26.40342	21.89968	25.25078	22.36804	25.74342	23.08150	25.10945	22.67396	24.69002	22.91038	25.72323	22.46959	25.45835	20.40925	25.06169	22.56207	24.93754	-2.354841	0.0000015	0.0000594
GO:0030650	peptide antibiotic metabolic process	biological_process	24.09145	26.44629	25.96161	27.03638	24.74310	25.04520	23.37240	27.40342	22.89968	26.25078	23.36804	26.74342	24.08150	26.10945	23.67396	25.69002	23.91038	26.72323	23.46959	26.45835	21.40925	26.06169	23.56207	25.93754	-2.354841	0.0000015	0.0000594
GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor	molecular_function	23.27120	25.61987	24.40390	25.18104	25.03357	26.31930	21.71014	24.80477	22.13888	25.09645	22.59010	24.88900	24.11673	26.81839	22.61148	24.02281	22.00834	26.14001	22.60199	26.21645	17.95866	23.84316	22.25756	25.48083	-2.348675	0.0002007	0.0011085
GO:0015771	trehalose transport	biological_process	19.02920	21.37694	19.31922	20.14075	17.56080	20.43652	18.27874	21.17920	17.88229	21.51292	15.87654	20.68225	21.04750	23.14649	16.94473	21.42628	19.13770	20.90463	19.71327	20.01724	17.22265	21.60392	NA	20.94386	-2.347739	0.0000478	0.0004975
GO:0015426	polar-amino acid-transporting ATPase activity	molecular_function	20.13323	22.47337	21.08641	21.99861	21.06255	22.30425	20.69812	22.53279	18.53835	21.62896	20.50844	22.75872	19.84465	23.03277	19.47562	23.09735	20.90815	22.44668	17.90376	21.59993	18.46222	22.71442	18.66374	22.23756	-2.340144	0.0000013	0.0000586
GO:0009002	serine-type D-Ala-D-Ala carboxypeptidase activity	molecular_function	24.26550	26.58743	23.79801	26.11698	21.20686	24.46583	24.04473	24.49301	22.12267	24.38079	24.61631	25.69501	25.34964	27.84474	22.59640	28.57708	24.87469	26.70454	25.15338	24.22353	22.18444	26.88220	25.07302	24.20318	-2.321925	0.0047142	0.0130613
GO:0001817	regulation of cytokine production	biological_process	24.57382	26.89051	25.12961	26.11635	24.16524	25.49210	20.65991	27.58252	24.09208	28.39372	22.39827	25.20931	23.74413	26.93544	21.02507	26.41623	23.98633	24.85291	26.31229	26.72474	25.33695	26.45319	25.08507	27.61195	-2.316685	0.0003422	0.0016204
GO:0001819	positive regulation of cytokine production	biological_process	22.98886	25.30554	23.54465	24.53139	22.58028	23.90714	19.07495	25.99755	22.50711	26.80876	20.81330	23.62435	22.15917	25.35048	19.44010	24.83127	22.40137	23.26795	24.72732	25.13978	23.75198	24.86822	23.50011	26.02699	-2.316685	0.0003422	0.0016204
GO:0032677	regulation of interleukin-8 production	biological_process	22.98886	25.30554	23.54465	24.53139	22.58028	23.90714	19.07495	25.99755	22.50711	26.80876	20.81330	23.62435	22.15917	25.35048	19.44010	24.83127	22.40137	23.26795	24.72732	25.13978	23.75198	24.86822	23.50011	26.02699	-2.316685	0.0003422	0.0016204
GO:0050707	regulation of cytokine secretion	biological_process	22.98886	25.30554	23.54465	24.53139	22.58028	23.90714	19.07495	25.99755	22.50711	26.80876	20.81330	23.62435	22.15917	25.35048	19.44010	24.83127	22.40137	23.26795	24.72732	25.13978	23.75198	24.86822	23.50011	26.02699	-2.316685	0.0003422	0.0016204
GO:0051047	positive regulation of secretion	biological_process	22.98886	25.30554	23.54465	24.53139	22.58028	23.90714	19.07495	25.99755	22.50711	26.80876	20.81330	23.62435	22.15917	25.35048	19.44010	24.83127	22.40137	23.26795	24.72732	25.13978	23.75198	24.86822	23.50011	26.02699	-2.316685	0.0003422	0.0016204
GO:2000484	positive regulation of interleukin-8 secretion	biological_process	21.98886	24.30554	22.54465	23.53139	21.58028	22.90714	18.07495	24.99755	21.50711	25.80876	19.81330	22.62435	21.15917	24.35048	18.44010	23.83127	21.40137	22.26795	23.72732	24.13978	22.75198	23.86822	22.50011	25.02699	-2.316685	0.0003422	0.0016204
GO:0004356	glutamate-ammonia ligase activity	molecular_function	24.45672	26.77236	24.69972	25.23596	25.03177	26.63772	23.85628	26.40082	23.45357	26.35942	23.96794	26.39947	24.73641	27.59279	23.63959	27.35172	25.07228	25.56638	25.11282	26.92802	24.29126	27.66449	23.88878	26.42239	-2.315639	0.0000002	0.0000216
GO:0004185	serine-type carboxypeptidase activity	molecular_function	24.27882	26.58880	23.79801	26.11698	21.20686	24.46583	24.05755	24.55606	22.12267	24.38079	24.61631	25.69501	25.34964	27.84474	22.59640	28.57708	24.92230	26.70454	25.15536	24.22353	22.41320	26.88220	25.07302	24.20318	-2.309982	0.0048005	0.0132735
GO:0042781	3’-tRNA processing endoribonuclease activity	molecular_function	19.56356	21.86506	21.58922	22.04203	20.92183	21.95431	17.57550	21.35030	15.04379	19.41319	18.25576	22.02451	19.10191	21.99011	17.87128	21.55468	19.46419	23.03638	19.38122	21.06084	18.80163	22.72228	17.41053	19.99065	-2.301494	0.0001761	0.0010182
GO:0002791	regulation of peptide secretion	biological_process	24.00543	26.30582	24.54465	25.53139	23.69723	24.91042	20.07495	26.99755	23.50711	27.80876	21.81330	24.62435	23.31328	26.35225	20.44010	25.83127	23.40137	24.26795	25.72732	26.13978	24.75198	25.86822	24.50011	27.02699	-2.300397	0.0003781	0.0017446
GO:0005275	amine transmembrane transporter activity	molecular_function	23.27459	25.57342	23.39947	25.02866	22.83573	24.97046	23.27850	25.42128	22.85217	25.05582	24.05409	26.24944	23.66056	26.16638	21.98613	25.73141	23.00708	25.16858	23.27256	24.78190	23.45385	26.47300	23.31536	24.92344	-2.298834	0.0000000	0.0000026
GO:0050708	regulation of protein secretion	biological_process	23.59222	25.89080	24.12961	25.11635	23.31916	24.49648	19.65991	26.58252	23.09208	27.39372	21.39827	24.20931	22.88191	25.93702	20.02507	25.41623	22.98633	23.85291	25.31229	25.72474	24.33695	25.45319	24.08507	26.61195	-2.298582	0.0003819	0.0017537
GO:0070008	serine-type exopeptidase activity	molecular_function	24.29052	26.58882	23.79801	26.11698	21.20686	24.46583	24.05755	24.55606	22.35998	24.38179	24.61631	25.69501	25.35844	27.84474	22.59640	28.57708	24.93204	26.70454	25.15536	24.22353	22.41320	26.88220	25.09454	24.20318	-2.298298	0.0049954	0.0137145
GO:0051046	regulation of secretion	biological_process	25.33063	27.62783	25.86658	26.85331	24.99651	26.23170	21.39688	28.31948	24.82904	29.13068	23.13523	25.94628	24.72034	27.67524	21.76203	27.15320	24.72330	25.58988	27.04925	27.46171	26.07391	27.19015	25.82204	28.34892	-2.297193	0.0003860	0.0017605
GO:1903530	regulation of secretion by cell	biological_process	24.01363	26.30599	24.54465	25.53139	23.69723	24.91042	20.07495	26.99755	23.50711	27.80876	21.81330	24.62435	23.45250	26.35402	20.44010	25.83127	23.40137	24.26795	25.72732	26.13978	24.75198	25.86822	24.50011	27.02699	-2.292362	0.0003976	0.0018011
GO:0033283	organic acid-transporting ATPase activity	molecular_function	23.30195	25.59061	23.41717	25.06183	22.83573	24.97046	23.27850	25.42128	22.85217	25.05582	24.05985	26.28054	23.66763	26.17402	21.98613	25.73141	23.32080	25.30202	23.27256	24.78190	23.45385	26.47300	23.28993	24.92308	-2.288659	0.0000000	0.0000026
GO:0010501	RNA secondary structure unwinding	biological_process	21.78112	24.06814	22.27435	23.61874	20.92550	23.76575	20.19948	24.09231	21.95263	23.10097	20.99968	24.54970	22.96706	24.42411	21.43874	23.86967	21.91734	23.64521	19.81439	23.48767	22.17153	25.37516	22.12385	23.04430	-2.287021	0.0000015	0.0000594
GO:0006203	dGTP catabolic process	biological_process	17.15224	19.43673	16.58627	18.74199	17.60223	18.50787	18.72544	20.26870	15.39371	19.56131	NA	19.48216	14.91470	18.55364	NA	NA	15.77883	18.91057	17.12253	19.49486	14.42648	19.78412	18.12197	19.92693	-2.284492	0.0000408	0.0004667
GO:0008662	1-phosphofructokinase activity	molecular_function	21.96350	24.23448	22.02683	23.33768	23.41561	24.12485	21.45657	24.41016	18.96749	24.54939	21.16933	23.61604	21.75459	24.88577	21.09579	24.25852	20.06220	23.84669	22.76627	23.68335	20.95664	24.96606	22.88211	23.94234	-2.270985	0.0000037	0.0001056
GO:0047849	dextransucrase activity	molecular_function	23.11922	25.36504	21.39249	25.49887	18.12167	22.23202	18.33584	23.67059	20.33267	25.90167	21.01077	24.18294	25.81279	27.18408	23.23005	26.01699	21.14617	25.14213	21.06739	23.31848	24.17151	25.65476	20.22751	22.78738	-2.245823	0.0007398	0.0028201
GO:0090087	regulation of peptide transport	biological_process	25.06962	27.30675	25.54465	26.53139	24.69723	25.91042	21.51207	27.99755	24.79197	28.81212	23.06606	25.62435	24.31328	27.35225	21.63172	26.83127	24.51416	25.26795	26.72732	27.13978	25.92205	26.86858	25.50572	28.02720	-2.237121	0.0004044	0.0018169
GO:0009651	response to salt stress	biological_process	24.29040	26.52144	25.53213	26.23868	24.24907	25.82479	24.63509	26.57538	23.00376	26.85039	24.62554	25.77059	23.24149	26.24819	23.70583	26.24095	24.30604	26.70327	24.69092	25.38523	23.28588	27.83543	23.86118	26.44170	-2.231038	0.0000003	0.0000259
GO:0102009	proline dipeptidase activity	molecular_function	23.67623	25.90313	25.06076	25.92935	24.41334	25.66954	22.76591	26.04450	22.61299	25.72986	22.83298	25.79480	23.41162	26.09496	22.70481	25.51291	24.52530	26.49082	22.54010	25.92423	22.95118	25.99991	23.60313	25.43229	-2.226902	0.0000000	0.0000039
GO:0006970	response to osmotic stress	biological_process	25.37660	27.58424	26.94440	27.63152	25.20772	26.91439	25.31709	27.54528	23.81648	27.83577	25.91124	26.95163	23.60271	26.25180	24.88612	27.10487	25.32923	27.98924	25.70122	25.61784	24.06783	29.14656	25.00093	27.40253	-2.207642	0.0000215	0.0003335
GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	molecular_function	22.68264	24.88851	23.10504	24.05997	22.74291	24.02198	19.99186	23.18487	20.28444	23.72950	22.92673	24.77501	22.10015	25.87496	21.17672	26.33401	24.59952	24.16342	22.25755	23.83820	22.74912	25.82725	21.68365	23.88762	-2.205866	0.0001460	0.0008916
GO:0030696	tRNA (m5U54) methyltransferase activity	molecular_function	20.20679	22.40353	20.70203	21.44431	20.68104	22.83806	20.29408	22.69244	21.15173	22.06966	19.64794	22.89556	20.62865	23.42038	18.87021	22.59854	18.85421	21.53700	18.91415	21.39371	19.24497	22.89077	20.77835	19.04652	-2.196738	0.0001612	0.0009580
GO:0030698	5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity	molecular_function	20.20679	22.40147	20.70203	21.44431	20.68104	22.83060	20.29408	22.69244	21.15173	22.06966	19.64794	22.88654	20.62865	23.42038	18.87021	22.59854	18.85421	21.53700	18.91415	21.39371	19.24497	22.89077	20.77835	19.04652	-2.194673	0.0001614	0.0009580
GO:0047151	methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity	molecular_function	20.20679	22.40147	20.70203	21.44431	20.68104	22.83060	20.29408	22.69244	21.15173	22.06966	19.64794	22.88654	20.62865	23.42038	18.87021	22.59854	18.85421	21.53700	18.91415	21.39371	19.24497	22.89077	20.77835	19.04652	-2.194673	0.0001614	0.0009580
GO:0050256	ribitol-5-phosphate 2-dehydrogenase activity	molecular_function	18.27130	20.46157	19.21966	20.50334	17.19099	18.17110	16.22632	19.84074	NA	NA	NA	20.74231	19.71166	20.45314	17.39817	19.24883	18.18000	20.70009	NA	19.77185	15.59591	21.75137	NA	20.76116	-2.190273	0.0007075	0.0027338
GO:0051223	regulation of protein transport	biological_process	24.13109	26.30767	24.54465	25.53139	23.69723	24.91042	20.84708	26.99755	24.02976	27.81547	22.28106	24.62435	23.31328	26.35225	20.80085	25.83127	23.61878	24.26795	25.72732	26.13978	25.07417	25.86894	24.51131	27.02742	-2.176581	0.0004511	0.0019824
GO:0099620	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	molecular_function	21.74410	23.91154	21.71299	23.73410	18.09742	21.12970	21.55374	24.72352	21.06220	23.84112	20.73694	24.26778	22.40145	24.03633	22.15180	23.25404	21.87739	23.88878	19.52898	23.19747	22.71890	24.72775	22.56208	23.76468	-2.167443	0.0001775	0.0010221
GO:0070201	regulation of establishment of protein localization	biological_process	24.46244	26.62977	24.86658	25.85331	23.99651	25.23170	21.20833	27.31948	24.38062	28.13785	22.62938	24.94628	23.64492	26.67430	21.30260	26.15320	23.95410	24.58988	26.04925	26.46171	25.41632	26.19130	24.83991	27.34960	-2.167332	0.0004348	0.0019215
GO:0010498	proteasomal protein catabolic process	biological_process	23.31133	25.47828	24.16147	25.37945	22.72936	23.89421	21.88904	26.57153	22.47133	22.53747	20.44969	24.45659	24.97356	24.96662	23.33160	26.78660	24.05889	25.44358	21.95390	25.95512	21.01413	21.59875	23.32285	25.92459	-2.166952	0.0038931	0.0111077
GO:0051050	positive regulation of transport	biological_process	23.73485	25.89495	24.12961	25.11635	23.16524	24.55292	20.61873	26.58252	23.75393	27.40267	21.99340	24.20931	22.74413	25.93544	20.02507	25.41623	23.26949	23.85291	25.31229	25.72474	24.74969	25.45319	24.08507	26.61195	-2.160104	0.0005105	0.0021618
GO:0015977	carbon fixation	biological_process	23.46287	25.62038	24.31189	24.76012	24.31811	25.66960	22.18234	24.86978	21.87201	24.13876	22.89286	25.93886	23.46288	26.70779	21.94263	26.10663	23.11844	25.16237	23.94881	25.40467	23.83825	26.23543	23.65003	24.80572	-2.157509	0.0000052	0.0001299
GO:0045151	acetoin biosynthetic process	biological_process	19.56622	21.71883	19.36561	21.12678	21.92607	22.22670	17.32799	21.14717	16.75963	19.85795	17.35977	20.41816	19.55968	23.15525	17.32003	20.89992	19.42588	22.11210	20.12013	22.77398	16.47318	20.67012	19.10483	20.44128	-2.152608	0.0001969	0.0010966
GO:0047605	acetolactate decarboxylase activity	molecular_function	19.56622	21.71883	19.36561	21.12678	21.92607	22.22670	17.32799	21.14717	16.75963	19.85795	17.35977	20.41816	19.55968	23.15525	17.32003	20.89992	19.42588	22.11210	20.12013	22.77398	16.47318	20.67012	19.10483	20.44128	-2.152608	0.0001969	0.0010966
GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity	molecular_function	18.51870	20.67025	18.74521	NA	15.72924	20.09842	19.92263	18.95059	NA	NA	17.71932	21.27153	14.14133	21.13703	NA	20.70903	20.00510	19.03817	NA	NA	16.78160	21.97685	16.85026	18.93838	-2.151545	0.0049744	0.0136846
GO:0051049	regulation of transport	biological_process	26.62106	28.71692	27.09796	27.93284	26.32755	27.35772	23.94652	29.39127	26.33506	30.20976	24.74521	27.03911	26.07930	28.75555	23.47671	28.22369	26.15651	26.76175	28.18802	28.53559	27.45717	28.36798	26.96622	29.43427	-2.095867	0.0004355	0.0019217
GO:0015766	disaccharide transport	biological_process	19.37272	21.46808	19.31922	20.14075	19.91941	21.48627	18.27874	21.17920	17.88229	21.51292	15.87654	20.68225	21.05746	23.14728	16.94473	21.42628	20.19690	21.19028	19.71327	20.01724	17.22265	21.60392	NA	20.94386	-2.095353	0.0002193	0.0011782
GO:0006116	NADH oxidation	biological_process	24.83296	26.91029	25.83245	26.31959	25.50105	26.59437	24.83161	26.71532	23.41381	26.69067	24.09413	26.32208	24.93400	27.79475	25.22511	26.78979	24.63678	26.83881	25.08116	27.03554	23.44401	27.35134	24.12510	26.86513	-2.077323	0.0000001	0.0000102
GO:0042910	xenobiotic transmembrane transporter activity	molecular_function	20.25294	22.32502	20.24813	21.84117	21.19725	22.16597	16.13427	20.47445	16.94765	21.13390	20.79350	23.56672	20.38442	22.91402	16.52009	19.95513	22.05848	23.46427	19.32674	21.03113	20.16849	22.48977	18.65413	22.14088	-2.072085	0.0013071	0.0044857
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	molecular_function	22.83056	24.90255	21.81578	23.09296	20.72122	23.99416	22.73268	25.76088	24.05035	25.71102	23.15304	24.27837	22.42457	25.22082	23.26454	24.87147	22.44357	24.91681	22.32095	24.00384	22.79039	25.06796	23.11028	25.00763	-2.071993	0.0000089	0.0001829
GO:0016297	acyl-[acyl-carrier-protein] hydrolase activity	molecular_function	18.14625	20.20631	20.33581	20.48298	17.56675	18.67935	15.78055	19.93470	13.54034	20.04959	14.58609	20.18531	19.05344	20.92399	NA	17.99571	16.61345	20.26887	NA	17.43473	16.01520	21.91072	NA	18.95580	-2.060061	0.0017820	0.0057593
GO:0015415	ATPase-coupled phosphate ion transmembrane transporter activity	molecular_function	21.21236	23.25486	21.87331	23.62154	22.43582	23.84393	20.48508	23.33417	21.32884	22.76295	19.68771	23.33796	21.59000	23.16415	19.81669	23.49325	22.08805	23.30999	20.23799	22.68057	19.93726	23.32091	20.50357	22.26448	-2.042500	0.0000009	0.0000505
GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity	molecular_function	17.65991	19.69934	19.20400	19.46087	16.56675	NA	NA	18.93470	NA	19.04959	13.58609	19.18531	18.05344	19.92399	NA	NA	15.61345	19.26887	NA	NA	NA	20.91072	NA	NA	-2.039430	0.0069047	0.0179125
GO:0009018	sucrose phosphorylase activity	molecular_function	19.49642	21.51822	20.63030	17.73214	21.31192	19.92814	17.51076	22.77792	14.18706	22.76672	15.83410	22.44687	21.04391	21.73669	17.92703	19.69108	18.38338	18.52646	19.19604	19.92127	16.06749	21.01145	17.76797	21.91448	-2.021803	0.0068134	0.0177043
GO:0008531	riboflavin kinase activity	molecular_function	20.81746	22.83668	21.44680	22.02245	21.07071	23.12853	20.35050	23.24008	19.40672	22.51094	20.73430	22.97193	20.86218	23.26563	20.88563	22.24291	20.36128	22.78748	20.57927	22.40920	20.30850	23.34412	21.71147	22.59863	-2.019226	0.0000000	0.0000033
GO:0004048	anthranilate phosphoribosyltransferase activity	molecular_function	17.60635	19.62293	NA	NA	14.36805	17.83015	NA	NA	NA	NA	17.28530	18.61039	19.67286	19.44606	NA	20.44754	15.72116	19.73252	NA	NA	15.62983	19.01394	16.21046	20.49118	-2.016581	0.0038673	0.0110530
GO:0034471	ncRNA 5’-end processing	biological_process	21.38391	23.39266	NA	NA	21.35519	22.59779	NA	23.40153	NA	NA	NA	NA	21.48475	22.89486	NA	23.28547	21.68028	23.47279	21.55074	23.02652	20.63889	24.35458	NA	NA	-2.008756	0.0000622	0.0005667
GO:0005985	sucrose metabolic process	biological_process	21.96702	23.96902	23.05982	23.00966	21.99407	23.46171	19.02604	23.75175	20.84081	23.74265	21.90428	23.94660	23.44337	25.37342	19.63247	24.21404	20.10338	22.70229	20.64081	22.62020	19.61664	24.87967	23.26099	23.13861	-2.002007	0.0001932	0.0010825
GO:0009099	valine biosynthetic process	biological_process	25.85521	27.84932	27.23686	26.59974	25.87440	27.61497	24.71510	27.89627	25.11996	27.56179	25.68217	26.91384	26.13059	28.68371	26.03003	28.87995	25.20219	27.52516	25.79472	27.56759	25.29393	28.00349	25.58261	27.51648	-1.994111	0.0000007	0.0000451
GO:0004457	lactate dehydrogenase activity	molecular_function	26.48318	28.47328	27.32517	27.90464	27.17693	28.69847	25.56079	28.72733	27.11973	28.43011	25.45433	27.63809	27.30315	28.86661	25.52747	28.95101	25.88343	28.50726	25.93702	28.40320	26.15009	28.36984	25.74170	28.18706	-1.990106	0.0000001	0.0000098
GO:0006573	valine metabolic process	biological_process	25.86989	27.85561	27.23935	26.61071	25.87440	27.61497	24.73361	27.90992	25.12217	27.57312	25.69810	26.93454	26.13059	28.68371	26.03262	28.88013	25.33426	27.53608	25.80918	27.57118	25.29859	28.01757	25.61116	27.51956	-1.985717	0.0000007	0.0000444
GO:0008955	peptidoglycan glycosyltransferase activity	molecular_function	20.84593	22.82778	22.81187	23.21739	21.12311	23.37689	19.64577	22.20861	20.66314	21.14761	21.44142	24.51361	20.88451	23.05693	18.83885	21.75297	19.84721	22.64686	19.50117	21.25727	19.93224	22.73548	19.34532	20.78487	-1.981849	0.0003876	0.0017646
GO:0052908	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity	molecular_function	20.60822	22.58690	21.40227	21.32227	20.48873	22.46558	20.00861	22.46113	19.81045	22.28108	20.81465	22.81580	20.60944	22.51676	19.13109	21.62407	21.27612	22.95083	21.03929	22.18048	20.36078	23.81876	20.31687	22.45292	-1.978678	0.0000009	0.0000512
GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity	molecular_function	21.03810	23.01292	22.50678	22.43553	21.26923	22.84811	19.67128	23.47188	21.00872	22.39652	20.47469	23.54754	21.76764	23.18795	20.37736	22.80427	21.14856	23.10600	20.10881	21.75698	20.20042	23.99680	20.20002	22.02693	-1.974819	0.0000031	0.0000910
GO:0071424	rRNA (cytosine-N4-)-methyltransferase activity	molecular_function	19.64757	21.61896	21.22848	20.23680	18.30998	20.55506	18.91229	20.33087	17.95169	22.61143	18.10771	20.10585	20.60711	23.29144	20.16734	21.05601	19.13124	19.24124	18.85022	20.69174	19.12545	22.95188	19.66204	19.81636	-1.971395	0.0033951	0.0099760
GO:0003962	cystathionine gamma-synthase activity	molecular_function	19.46037	21.42496	19.60657	21.75071	NA	NA	19.63029	21.79981	16.80282	20.59359	19.22665	22.73318	20.41626	20.98319	18.37712	20.98350	20.58919	21.57331	18.48745	18.07501	19.04337	21.98932	19.31224	19.44720	-1.964589	0.0036084	0.0104810
GO:0005789	endoplasmic reticulum membrane	cellular_component	20.69968	22.65697	20.48586	20.63097	NA	NA	20.21049	22.23175	20.31977	23.09805	20.77846	NA	20.26795	24.24177	NA	21.10471	NA	NA	18.72146	21.72006	21.70381	22.00087	21.37759	22.86427	-1.957288	0.0043852	0.0122750
GO:0043892	methylglyoxal reductase (NADPH-dependent) activity	molecular_function	20.95507	22.91139	20.18417	22.40548	21.16926	22.68567	19.90034	23.31946	19.53216	23.17981	19.50279	22.88342	21.50690	23.05243	17.73798	22.38066	20.79011	22.43420	20.01298	21.20002	23.01165	24.16608	20.78404	22.44462	-1.956314	0.0000525	0.0005111
GO:0009399	nitrogen fixation	biological_process	24.74406	26.70011	24.68803	25.22771	26.00954	26.66503	24.29783	26.45270	23.89347	26.32014	24.10703	26.18317	24.90666	27.54780	23.55073	26.85772	25.35680	25.44520	25.15339	26.94123	24.45189	27.52148	23.66093	26.79887	-1.956045	0.0000044	0.0001180
GO:0004107	chorismate synthase activity	molecular_function	20.23921	22.19462	21.63254	22.91471	20.57108	21.56272	18.94733	21.31391	17.14200	21.29167	20.55439	23.04835	21.16453	22.70898	19.71063	22.33944	18.75651	22.03144	20.38400	20.64886	18.90535	22.82056	20.07540	21.22202	-1.955404	0.0001221	0.0007844
GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity	molecular_function	20.63585	22.58769	21.40227	21.32227	20.48873	22.46558	20.00861	22.46113	19.81045	22.28108	20.81465	22.81580	20.60944	22.51676	19.13109	21.62407	21.45737	22.95755	21.03929	22.18048	20.36078	23.81876	20.31687	22.45292	-1.951839	0.0000014	0.0000586
GO:1903047	mitotic cell cycle process	biological_process	21.80524	23.75067	NA	NA	NA	NA	21.60564	NA	21.38437	22.55369	21.61596	23.81745	22.10710	23.85544	21.48417	22.65461	21.19815	23.48455	21.91657	24.48638	22.35789	24.52842	22.14833	23.35872	-1.945428	0.0000099	0.0001950
GO:0009082	branched-chain amino acid biosynthetic process	biological_process	27.35253	29.28860	28.42667	28.00242	27.30313	29.05186	26.29816	29.11152	26.70003	28.94777	27.24243	28.50729	27.64310	30.19892	27.58227	30.29225	27.20475	28.85762	27.30226	28.93881	26.99569	29.68924	27.09926	28.88180	-1.936064	0.0000006	0.0000439
GO:0008967	phosphoglycolate phosphatase activity	molecular_function	18.97585	20.90671	17.23743	20.87768	18.40253	19.17587	18.46749	20.61124	16.87106	20.45136	19.61340	21.05936	20.00658	22.24586	15.50433	21.31972	19.65852	20.98949	19.41159	17.83661	19.57028	21.22569	18.88083	20.54054	-1.930858	0.0013643	0.0046702
GO:0042277	peptide binding	molecular_function	20.39798	22.31135	20.10057	21.59515	18.65066	21.63874	19.97178	21.38616	19.86203	21.16143	14.28788	22.33851	17.35438	23.18915	19.31705	22.38669	22.91404	21.59542	16.52278	21.55248	20.96040	24.12296	19.61446	19.72377	-1.913372	0.0016422	0.0054366
GO:0047850	diaminopimelate dehydrogenase activity	molecular_function	22.64853	24.56121	NA	NA	NA	NA	22.11078	25.01937	21.87811	25.33171	22.67817	24.24953	22.24358	24.33248	23.17948	24.17994	22.84126	24.16008	22.74309	23.74852	23.16046	23.19208	22.44328	25.39294	-1.912685	0.0000099	0.0001950
GO:0015079	potassium ion transmembrane transporter activity	molecular_function	21.89361	23.80465	21.28522	23.45612	22.06576	23.16026	21.27459	22.59583	22.19299	24.65102	21.68230	23.59062	20.48121	23.97018	22.27305	24.43248	22.09881	23.87409	22.32870	23.43245	21.60460	23.71419	22.45143	23.88072	-1.911032	0.0000002	0.0000203
GO:0042282	hydroxymethylglutaryl-CoA reductase activity	molecular_function	18.29105	20.19726	18.74521	NA	15.72924	20.09842	19.92263	18.95059	NA	NA	17.71932	21.27153	NA	18.39496	NA	NA	NA	NA	NA	NA	16.65158	21.07270	16.85026	18.93838	-1.906209	0.0206284	0.0431158
GO:0010243	response to organonitrogen compound	biological_process	22.51462	24.41943	NA	NA	22.67388	23.69295	21.88133	25.57480	21.62240	21.53944	23.00839	NA	20.29972	23.96730	22.60323	NA	23.77013	24.64358	22.17132	25.00135	20.80438	21.07285	23.12964	25.04066	-1.904815	0.0235294	0.0476195
GO:0035375	zymogen binding	molecular_function	22.52107	24.42544	24.66634	23.80671	22.77433	24.32154	21.60027	24.55677	21.72439	25.07028	18.98391	22.49995	22.99632	23.94010	21.55685	24.82092	22.19080	24.27017	NA	NA	20.52379	24.55927	20.49630	24.98245	-1.904368	0.0002184	0.0011756
GO:0004743	pyruvate kinase activity	molecular_function	27.38648	29.28029	28.49604	28.95894	27.92303	29.32552	26.58780	29.13114	25.89020	29.09519	27.09172	29.21693	27.54028	29.60806	27.01509	29.26814	27.47846	29.42422	27.76753	29.15337	26.73956	29.74137	26.98072	28.93197	-1.893815	0.0000000	0.0000035
GO:0051240	positive regulation of multicellular organismal process	biological_process	23.51307	25.40257	23.63434	24.55866	22.68111	24.10930	21.77303	26.08382	23.49518	26.82599	22.55705	23.69643	22.86793	25.51077	21.43869	25.15851	23.30909	23.52230	25.01190	25.19412	24.17140	25.09768	23.99708	26.05683	-1.889503	0.0003839	0.0017566
GO:0042776	mitochondrial ATP synthesis coupled proton transport	biological_process	22.69064	24.57980	22.89350	23.00656	23.65827	24.19731	20.30707	24.73443	23.18356	24.75399	22.41207	23.58124	23.70845	25.14020	21.93305	25.46968	22.14682	23.75354	22.57712	24.58352	22.12418	25.34733	21.87505	23.73887	-1.889166	0.0000439	0.0004759
GO:0008988	rRNA (adenine-N6-)-methyltransferase activity	molecular_function	20.70210	22.59040	21.40227	21.32227	20.48873	22.46558	20.00861	22.46113	19.81045	22.28108	20.96301	22.81580	20.62442	22.52770	19.13109	21.62407	21.38209	22.95109	21.38257	22.19841	20.36078	23.81876	20.51596	22.46833	-1.888296	0.0000027	0.0000851
GO:0009403	toxin biosynthetic process	biological_process	23.59127	25.47243	24.97954	26.03638	25.50804	24.39497	22.37240	26.40342	22.06487	25.25137	22.41790	25.74342	23.37980	25.24027	22.72239	24.69870	23.21337	25.72583	22.74273	25.47324	20.54032	25.06940	22.67428	24.94046	-1.881167	0.0000286	0.0003940
GO:0044448	cell cortex part	cellular_component	23.80825	25.68691	24.87908	25.56464	25.41762	25.24739	21.87351	26.28382	22.27228	24.62084	23.08600	25.53314	24.02295	25.65908	22.97653	26.07096	23.73466	25.60262	23.61991	26.01729	21.91317	25.24695	23.51589	25.98706	-1.878662	0.0000071	0.0001554
GO:0009151	purine deoxyribonucleotide metabolic process	biological_process	18.44499	20.31989	17.58627	19.74199	18.60223	19.50787	20.68573	21.26870	16.39371	20.56131	13.49503	20.48216	15.91470	19.55364	16.21205	17.64351	16.77883	19.91057	18.12253	20.49486	15.42648	20.78412	19.88295	20.92693	-1.874898	0.0004612	0.0020087
GO:0009215	purine deoxyribonucleoside triphosphate metabolic process	biological_process	18.44499	20.31989	17.58627	19.74199	18.60223	19.50787	20.68573	21.26870	16.39371	20.56131	13.49503	20.48216	15.91470	19.55364	16.21205	17.64351	16.77883	19.91057	18.12253	20.49486	15.42648	20.78412	19.88295	20.92693	-1.874898	0.0004612	0.0020087
GO:0009404	toxin metabolic process	biological_process	24.59894	26.47225	25.97954	27.03638	26.50815	25.39497	23.37240	27.40342	23.09893	26.25146	23.41790	26.74342	24.38143	26.24034	23.72239	25.69870	24.30412	26.72602	23.74048	26.47211	21.54032	26.06771	23.67428	25.94046	-1.873311	0.0000302	0.0004042
GO:0047206	UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity	molecular_function	19.59975	21.47012	21.22363	21.92976	20.70837	NA	17.58705	18.84827	16.89928	20.47452	19.25246	22.35767	19.53467	21.68853	NA	20.95394	17.83033	22.08516	19.00303	21.17393	NA	21.47612	19.00775	21.31484	-1.870367	0.0009541	0.0034719
GO:0005754	mitochondrial proton-transporting ATP synthase, catalytic core	cellular_component	22.71601	24.58541	22.99800	23.03478	23.66113	24.20862	20.35932	24.74853	23.24651	24.75399	22.41239	23.58947	23.70845	25.14020	21.93305	25.46968	22.21815	23.77499	22.57712	24.58352	22.12418	25.35403	21.87505	23.73887	-1.869405	0.0000464	0.0004873
GO:0102250	linear malto-oligosaccharide phosphorylase activity	molecular_function	23.93517	25.80446	24.11518	24.98256	24.73808	24.61863	23.19121	25.40371	23.24374	25.66149	23.49619	24.43525	24.61366	26.65823	23.73757	26.66605	23.43824	25.60893	23.63152	25.47980	23.44847	26.54116	24.48467	25.77845	-1.869285	0.0000044	0.0001180
GO:0030955	potassium ion binding	molecular_function	27.59343	29.45568	28.58206	29.00876	28.35923	29.73288	26.94013	29.28272	26.46316	29.14394	27.18317	29.26002	27.87657	29.97269	27.09800	29.32796	27.41991	29.45512	27.88720	29.42607	26.99905	29.85361	27.21487	29.21362	-1.862254	0.0000000	0.0000029
GO:0032879	regulation of localization	biological_process	27.20686	29.06906	27.41790	28.25302	26.62748	27.74909	25.25009	29.73955	27.27917	30.52961	26.01276	27.39308	26.61174	29.13741	24.68895	28.69207	26.95436	27.18668	28.62248	28.86842	28.09357	28.76043	27.51071	29.75379	-1.862203	0.0006377	0.0025533
GO:0070395	lipoteichoic acid biosynthetic process	biological_process	24.22760	26.08946	25.67396	26.39229	24.93721	26.15979	24.51894	26.59097	22.39809	25.66152	23.44169	26.63496	23.57102	26.27812	23.66226	25.70593	24.20288	26.04754	23.19167	25.52470	21.56553	25.55378	24.91949	25.86242	-1.861861	0.0000108	0.0002059
GO:0043799	glycine oxidase activity	molecular_function	17.66557	19.52366	18.92239	18.80648	18.09651	18.13230	16.45271	21.03493	NA	NA	NA	19.56949	17.50136	19.11606	NA	NA	17.20258	18.97742	NA	NA	15.43368	18.98609	NA	NA	-1.858088	0.0067883	0.0176560
GO:0009275	Gram-positive-bacterium-type cell wall	cellular_component	21.04596	22.88989	17.80807	19.41016	16.47018	20.64217	NA	23.86647	20.13915	25.17054	16.81268	20.07762	19.65658	22.95052	16.26652	21.49097	18.91358	20.56875	23.49723	22.38640	22.58816	22.56148	18.97459	22.16874	-1.843934	0.0063196	0.0166601
GO:0008134	transcription factor binding	molecular_function	25.48547	27.32927	24.91928	26.58995	23.68376	26.73467	25.43367	27.59433	26.61840	27.95546	25.94078	26.24057	25.86835	27.37518	25.36744	27.52515	24.55253	28.24431	24.57674	27.05614	24.51953	25.97618	26.26378	27.64081	-1.843802	0.0000176	0.0002881
GO:0004180	carboxypeptidase activity	molecular_function	25.51829	27.35468	26.17523	26.68582	25.41164	26.03963	25.13619	25.10132	24.82512	24.92488	25.87920	26.60108	26.03467	28.53875	24.86671	29.35316	25.81285	26.88569	25.59212	25.51043	23.94424	27.82191	25.71064	25.75192	-1.836389	0.0149284	0.0330418
GO:0004795	threonine synthase activity	molecular_function	22.06005	23.89641	22.78526	23.07227	22.49942	23.56761	21.45735	23.57152	20.61519	23.38231	22.38432	23.50463	22.10941	24.69862	21.05476	24.63192	21.45907	22.24583	22.72695	23.83675	22.37981	24.91646	21.51411	23.30449	-1.836356	0.0000190	0.0003017
GO:0009097	isoleucine biosynthetic process	biological_process	26.36380	28.19901	27.50196	27.01517	26.45580	27.98457	25.30810	28.09483	25.53799	27.87171	26.22979	27.57343	26.69668	29.05206	26.34447	29.08013	26.42447	27.81921	26.24495	27.90521	25.99467	28.62249	26.02792	27.78176	-1.835210	0.0000007	0.0000448
GO:0019748	secondary metabolic process	biological_process	25.80901	27.64348	26.73426	28.02956	27.96093	27.00278	24.20259	28.12270	24.02164	27.36339	24.61924	27.54620	25.07261	27.60127	24.36614	27.56624	25.62045	27.91547	25.86348	27.67819	23.78013	27.69434	24.72367	27.15489	-1.834470	0.0000059	0.0001363
GO:0002099	tRNA wobble guanine modification	biological_process	18.60750	20.43311	18.29710	20.03596	18.68579	21.01124	17.64861	20.51049	16.80536	18.65714	18.98695	20.43858	19.02270	21.31391	17.05187	19.37830	19.72095	20.33367	18.31152	20.74932	18.93963	20.59372	18.77756	20.07071	-1.825611	0.0000269	0.0003880
GO:0044550	secondary metabolite biosynthetic process	biological_process	24.44980	26.27511	25.22253	26.60204	26.66948	25.74428	22.72619	26.60048	22.56215	25.96479	23.20662	26.04145	23.53290	26.28789	22.80970	26.33990	24.26923	26.55152	24.68787	26.32610	22.62565	26.44119	23.27658	25.80040	-1.825314	0.0000059	0.0001363
GO:0006537	glutamate biosynthetic process	biological_process	24.99725	26.82220	25.18775	26.52658	26.59945	26.86198	24.27706	26.14909	24.45663	26.44995	24.59320	26.84285	25.28720	27.07657	24.16492	26.12019	24.39951	27.11352	24.59108	27.09282	24.52523	27.42487	24.76606	26.80340	-1.824955	0.0000001	0.0000101
GO:0009081	branched-chain amino acid metabolic process	biological_process	28.43707	30.26049	29.46381	28.95980	28.89117	30.14044	27.30030	30.09698	27.68318	29.93125	28.25797	29.47064	28.60631	31.14756	28.55859	31.23978	28.19028	29.83453	28.43555	29.91407	28.16646	30.62373	28.07598	29.88073	-1.823417	0.0000018	0.0000626
GO:0004479	methionyl-tRNA formyltransferase activity	molecular_function	20.96956	22.78001	20.75904	22.04588	21.66708	21.84140	18.45121	22.90389	20.63063	22.67959	21.23736	23.52915	21.86498	23.15838	20.24740	22.35663	20.86730	21.94610	20.95961	22.52621	19.87978	23.59399	21.53912	22.73688	-1.810442	0.0000165	0.0002755
GO:0071014	post-mRNA release spliceosomal complex	cellular_component	21.98693	23.79721	NA	24.37607	20.55846	22.74062	NA	NA	22.50810	23.22285	NA	24.13710	21.68821	23.91600	21.45114	23.33995	22.28455	24.54695	NA	NA	22.53434	23.04248	NA	NA	-1.810287	0.0004606	0.0020087
GO:0004837	tyrosine decarboxylase activity	molecular_function	20.97643	22.77738	19.95090	20.60498	21.54521	22.25676	20.76538	23.67549	NA	NA	20.19971	23.43894	21.09680	23.74109	19.98151	21.15342	22.14549	21.08938	20.80095	22.56299	21.08616	23.05594	20.61056	22.74184	-1.800949	0.0012018	0.0041763
GO:0044431	Golgi apparatus part	cellular_component	19.93935	21.73804	19.62004	20.74377	18.65066	21.46177	16.30499	21.17013	19.88601	21.30942	22.38785	21.66444	16.27404	21.56876	17.09696	22.53271	19.16334	21.86266	NA	NA	20.21348	22.99707	18.07709	19.39354	-1.798683	0.0008782	0.0032477
GO:0047480	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	molecular_function	21.36599	23.16067	21.48564	22.30038	22.27797	22.52552	21.91205	23.55691	21.50428	22.90448	21.16601	23.25889	21.04153	23.80174	20.58038	23.55615	20.86102	22.61916	20.67099	22.90522	20.71198	23.75046	21.70403	22.59747	-1.794682	0.0000002	0.0000184
GO:0044650	adhesion of symbiont to host cell	biological_process	21.16970	22.96150	18.21270	19.41016	16.47018	20.64217	19.49363	24.06874	20.69811	25.18594	17.08566	20.34018	20.63595	22.98647	16.50007	21.49097	19.97603	20.68813	23.59478	22.43299	22.58816	22.56863	20.25066	22.41394	-1.791800	0.0118803	0.0277650
GO:0008964	phosphoenolpyruvate carboxylase activity	molecular_function	23.85122	25.64258	24.42154	24.80506	24.31811	25.68255	23.47729	24.89843	22.02171	24.20172	24.14469	25.95856	23.61032	26.72957	22.95116	26.10663	22.87020	25.18357	24.38026	25.42383	24.37506	26.25756	23.96881	24.85669	-1.791360	0.0000278	0.0003938
GO:0030320	cellular monovalent inorganic anion homeostasis	biological_process	21.07992	22.86932	21.48218	23.62672	22.49466	23.33896	18.16950	21.88531	20.06698	20.53532	21.63850	23.17889	22.10124	23.71626	19.60195	22.29368	20.33184	22.72531	21.14044	22.65023	19.69212	23.38458	20.08497	21.21865	-1.789402	0.0007097	0.0027338
GO:0055083	monovalent inorganic anion homeostasis	biological_process	22.07992	23.86932	22.48218	24.62672	23.49466	24.33896	19.16950	22.88531	21.06698	21.53532	22.63850	24.17889	23.10124	24.71626	20.60195	23.29368	21.33184	23.72531	22.14044	23.65023	20.69212	24.38458	21.08497	22.21865	-1.789402	0.0007097	0.0027338
GO:0030002	cellular anion homeostasis	biological_process	22.66488	24.45403	23.06714	25.21169	24.07963	24.92392	19.75446	23.47027	21.65194	22.12028	23.22346	24.76385	23.68620	25.30123	21.18691	23.87450	21.91681	24.31028	22.72540	24.23519	21.27709	24.96954	21.66993	22.80361	-1.789149	0.0007113	0.0027338
GO:0030643	cellular phosphate ion homeostasis	biological_process	21.07992	22.86894	21.48218	23.62672	22.49466	23.33896	18.16950	21.88531	20.06698	20.53532	21.63850	23.17889	22.10124	23.71626	19.60195	22.28746	20.33184	22.72531	21.14044	22.65023	19.69212	23.38458	20.08497	21.21865	-1.789023	0.0007121	0.0027338
GO:0072505	divalent inorganic anion homeostasis	biological_process	22.07992	23.86894	22.48218	24.62672	23.49466	24.33896	19.16950	22.88531	21.06698	21.53532	22.63850	24.17889	23.10124	24.71626	20.60195	23.28746	21.33184	23.72531	22.14044	23.65023	20.69212	24.38458	21.08497	22.21865	-1.789023	0.0007121	0.0027338
GO:0072506	trivalent inorganic anion homeostasis	biological_process	22.07992	23.86894	22.48218	24.62672	23.49466	24.33896	19.16950	22.88531	21.06698	21.53532	22.63850	24.17889	23.10124	24.71626	20.60195	23.28746	21.33184	23.72531	22.14044	23.65023	20.69212	24.38458	21.08497	22.21865	-1.789023	0.0007121	0.0027338
GO:0046166	glyceraldehyde-3-phosphate biosynthetic process	biological_process	24.22925	26.01790	25.04475	26.30436	25.70949	26.67757	23.05351	25.79880	23.18041	24.81896	24.20544	25.49787	24.77136	25.96276	22.37067	24.94801	23.52758	25.34454	24.84569	26.89883	21.97478	26.89448	23.08072	24.91349	-1.788653	0.0001400	0.0008585
GO:0097305	response to alcohol	biological_process	20.91309	22.70119	20.00157	21.81899	20.78517	22.91721	17.60946	22.43918	21.30120	22.37042	17.32786	21.17419	19.87900	22.60804	18.89513	23.65924	21.03552	23.01538	22.31833	20.48850	22.62892	24.16647	19.18891	20.51375	-1.788104	0.0025118	0.0077316
GO:0003872	6-phosphofructokinase activity	molecular_function	25.34674	27.13238	25.54860	26.70633	25.77613	26.80884	25.43494	27.31452	24.90411	26.35016	25.15306	26.73329	25.39291	27.78655	24.77937	27.37378	25.42298	27.30476	25.73281	27.29748	24.99850	27.18718	25.31163	27.04230	-1.785636	0.0000000	0.0000002
GO:0004004	ATP-dependent RNA helicase activity	molecular_function	22.79062	24.57567	23.55470	24.18030	23.50499	24.94835	21.74200	24.54828	17.85753	23.28319	22.38738	24.95151	23.29473	24.98931	23.02216	24.41419	23.05320	24.16941	21.70833	23.85339	22.60923	25.62166	23.10392	23.85362	-1.785046	0.0007750	0.0029297
GO:0052588	diacetyl reductase ((S)-acetoin forming) activity	molecular_function	23.84222	25.62672	22.81660	25.58625	26.23539	25.72942	22.13309	24.56500	22.25401	25.06070	22.94957	24.54655	21.02959	26.16852	19.15509	26.00570	23.03492	25.83299	25.19495	25.78528	21.20597	26.06513	23.13205	25.54536	-1.784498	0.0001191	0.0007735
GO:0045982	negative regulation of purine nucleobase metabolic process	biological_process	20.77560	22.55278	21.39161	22.20835	21.68803	22.86052	18.22086	23.07735	17.78083	22.69640	20.58084	22.39917	21.23111	22.60911	18.64194	21.43421	21.03950	21.87873	21.16711	22.40692	21.65441	23.23576	19.67184	22.39435	-1.777175	0.0001289	0.0008111
GO:0046374	teichoic acid metabolic process	biological_process	25.44308	27.21948	26.90141	27.52823	26.13937	27.21485	25.58288	27.69223	23.53700	26.78123	24.61250	27.75755	25.00104	27.35714	24.71008	26.78350	25.54567	27.23526	24.42952	26.62083	23.62327	26.85919	26.03844	27.06271	-1.776398	0.0000056	0.0001355
GO:0019350	teichoic acid biosynthetic process	biological_process	24.45453	26.23036	25.90601	26.53368	25.14159	26.21694	24.58912	26.69389	22.62168	25.79377	23.64855	26.77177	24.01500	26.36179	23.71777	25.79102	24.55726	26.24385	23.45054	25.63312	22.62712	25.89165	25.05192	26.09121	-1.775830	0.0000050	0.0001292
GO:0004421	hydroxymethylglutaryl-CoA synthase activity	molecular_function	21.39558	23.17066	22.06467	23.10528	22.47166	22.86291	19.14294	22.69570	18.68396	21.29841	22.51493	24.42896	21.37283	23.15628	20.39538	22.26011	20.68154	23.50616	21.58232	22.79555	20.98776	23.91724	21.03861	22.47846	-1.775079	0.0003122	0.0015271
GO:0008443	phosphofructokinase activity	molecular_function	25.54028	27.31463	25.66904	26.83965	26.03280	27.01750	25.64382	27.49578	25.02684	26.71420	25.25301	26.89136	25.50822	27.96784	24.97331	27.53161	25.82163	27.43546	25.91464	27.41074	25.08353	27.46751	25.55756	27.20145	-1.774348	0.0000000	0.0000002
GO:0006307	DNA dealkylation involved in DNA repair	biological_process	19.13242	20.90663	18.92265	21.94985	NA	18.30885	20.08900	21.16242	20.00066	20.58058	15.62679	21.85945	18.98812	19.20515	19.37848	20.41595	19.63871	20.82836	17.02753	19.79307	18.72297	22.03178	18.78239	18.82858	-1.774209	0.0078943	0.0199783
GO:0008556	potassium-transporting ATPase activity	molecular_function	20.55685	22.32516	20.06389	22.53043	20.20933	22.79529	20.58582	21.81143	18.38682	20.57370	20.88724	23.22741	19.35432	23.11289	19.48816	20.90824	21.10196	22.08070	21.59021	22.00745	20.32227	22.05135	21.35309	22.35517	-1.768308	0.0001100	0.0007546
GO:0006002	fructose 6-phosphate metabolic process	biological_process	26.38299	28.14970	27.13006	27.90515	26.96852	28.17145	26.06982	28.23523	25.87222	27.70432	25.94963	27.65600	26.70452	28.50257	25.86001	28.17490	26.18647	28.38948	26.53327	28.13377	26.05106	28.30729	26.15065	28.22703	-1.766711	0.0000000	0.0000002
GO:0034026	L-amino-acid alpha-ligase activity	molecular_function	18.77107	20.53403	20.59537	20.99069	NA	NA	14.48492	NA	17.14855	18.98338	18.57979	20.25244	NA	NA	NA	NA	17.34734	20.33241	NA	NA	NA	21.02576	18.50925	20.78243	-1.762961	0.0143053	0.0319226
GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	biological_process	21.53207	23.29483	NA	NA	20.66348	23.17136	NA	NA	22.24356	22.27237	NA	24.05093	NA	NA	NA	NA	21.20025	23.27641	20.47820	22.26072	22.15368	24.25195	NA	22.24725	-1.762768	0.0056523	0.0152108
GO:0051185	coenzyme transmembrane transporter activity	molecular_function	19.05912	20.82133	NA	NA	18.83027	17.53111	NA	21.41856	17.81214	20.84460	17.74476	NA	20.25310	20.02192	NA	21.01464	18.05216	21.16192	20.70060	21.24978	14.80468	21.60135	17.60734	19.18430	-1.762207	0.0110073	0.0261978
GO:0044651	adhesion of symbiont to host epithelial cell	biological_process	21.13242	22.89436	17.80807	19.41016	16.47018	20.64217	NA	23.86647	20.22705	25.17327	16.81268	20.07762	19.65658	22.95052	16.26652	21.49097	19.96907	20.57926	23.58379	22.42574	22.58816	22.56863	18.97459	22.16874	-1.761938	0.0088888	0.0220234
GO:0045936	negative regulation of phosphate metabolic process	biological_process	21.11438	22.86929	21.48218	23.62672	22.49466	23.33896	18.16950	21.88531	20.06698	20.53532	21.63850	23.17889	22.10124	23.71626	19.60195	22.28746	20.86451	22.72957	21.14044	22.65023	19.69212	23.38458	20.08497	21.21865	-1.754914	0.0008865	0.0032650
GO:0004021	L-alanine:2-oxoglutarate aminotransferase activity	molecular_function	22.87070	24.62464	23.30454	24.07090	23.42154	25.25186	22.47288	24.07254	21.17227	24.40737	22.67423	24.78543	23.92935	24.70492	22.06062	24.58638	21.78934	25.10778	23.30202	24.42531	22.56517	24.81827	22.81313	24.04813	-1.753936	0.0000009	0.0000512
GO:0102908	quarternary amine transporter activity	molecular_function	17.61492	19.36828	16.35500	20.34044	16.19115	19.91703	NA	NA	NA	17.96326	NA	18.66286	19.42021	18.27223	NA	NA	16.73456	19.15921	15.07116	19.69211	NA	NA	NA	NA	-1.753356	0.0077822	0.0197683
GO:0042274	ribosomal small subunit biogenesis	biological_process	23.00401	24.74242	23.71974	23.86528	23.20319	24.14805	22.47890	24.33137	22.44372	23.98222	22.93313	24.26789	23.15029	24.67258	22.22443	24.06176	23.19994	26.66952	22.96656	23.99045	22.61098	24.99339	23.39788	23.92559	-1.738408	0.0000300	0.0004031
GO:0009155	purine deoxyribonucleotide catabolic process	biological_process	17.70199	19.43673	16.58627	18.74199	17.60223	18.50787	19.68573	20.26870	15.39371	19.56131	NA	19.48216	14.91470	18.55364	NA	NA	15.77883	18.91057	17.12253	19.49486	14.42648	19.78412	18.88295	19.92693	-1.734737	0.0004279	0.0018973
GO:0009217	purine deoxyribonucleoside triphosphate catabolic process	biological_process	17.70199	19.43673	16.58627	18.74199	17.60223	18.50787	19.68573	20.26870	15.39371	19.56131	NA	19.48216	14.91470	18.55364	NA	NA	15.77883	18.91057	17.12253	19.49486	14.42648	19.78412	18.88295	19.92693	-1.734737	0.0004279	0.0018973
GO:0019184	nonribosomal peptide biosynthetic process	biological_process	23.32616	25.04778	22.53293	24.97768	25.81466	25.02528	20.52512	23.63102	20.78401	24.60681	22.01843	23.71548	20.23326	25.34708	18.71991	25.74522	23.70739	25.37158	24.25408	25.16224	22.21973	25.74547	21.40586	24.62558	-1.721617	0.0002359	0.0012404
GO:0016838	carbon-oxygen lyase activity, acting on phosphates	molecular_function	22.97776	24.68813	23.57553	24.54742	22.93043	24.04089	22.25273	24.18305	20.91803	23.99663	23.21526	24.87583	23.40349	25.56978	23.32573	25.21566	22.85510	24.00105	23.25056	24.21789	23.05430	25.47498	22.45892	24.04304	-1.710371	0.0000097	0.0001947
GO:0015658	branched-chain amino acid transmembrane transporter activity	molecular_function	20.87764	22.58365	21.71137	21.45651	21.22527	21.99821	20.82818	21.88451	20.51279	22.41607	20.99008	22.25887	20.98054	23.61117	20.84629	23.62826	20.36118	22.31670	20.38114	21.55495	20.29129	22.72603	20.87032	22.64679	-1.706011	0.0000037	0.0001056
GO:0045149	acetoin metabolic process	biological_process	24.50694	26.18973	23.44737	26.07267	26.79882	26.09392	22.57359	25.20843	23.35588	25.66660	23.91707	25.82246	22.00275	26.71124	19.60657	26.34932	24.61505	26.56556	25.57792	26.34008	22.05789	26.36888	23.94040	26.29068	-1.682785	0.0002096	0.0011371
GO:0004610	phosphoacetylglucosamine mutase activity	molecular_function	20.75313	22.43064	21.65083	23.23814	21.94906	20.17944	17.78560	23.06784	18.61273	21.78514	19.05371	22.39326	20.70222	22.57760	18.47246	22.15443	20.03177	23.04607	19.66026	21.94535	19.25792	20.98046	22.59398	22.83712	-1.677510	0.0006547	0.0026130
GO:0004722	protein serine/threonine phosphatase activity	molecular_function	22.52257	24.19622	24.09573	24.88876	23.28206	23.05647	20.93375	24.36162	21.15735	23.32420	22.35463	25.08876	22.47133	23.60676	21.05513	23.33053	22.14821	24.69886	23.14335	24.33999	21.44485	24.47261	21.81225	23.07466	-1.673644	0.0001043	0.0007288
GO:0045150	acetoin catabolic process	biological_process	24.45919	26.12316	23.35955	26.02508	26.74872	25.99151	22.53505	25.11931	23.34090	25.64062	23.90167	25.78799	21.70958	26.58304	19.27566	26.31592	24.57495	26.49816	25.54472	26.21282	22.02751	26.34083	23.88897	26.26544	-1.663972	0.0002788	0.0014113
GO:0047200	tetrahydrodipicolinate N-acetyltransferase activity	molecular_function	22.32433	23.98591	24.09383	24.30234	23.27776	23.51206	21.49568	24.08457	21.21930	23.36336	21.87951	24.53344	22.03134	24.27462	20.53080	23.82719	21.88337	24.04164	22.10132	23.59389	20.43978	23.22758	22.20817	24.41115	-1.661573	0.0000137	0.0002435
GO:0004791	thioredoxin-disulfide reductase activity	molecular_function	24.60678	26.26810	25.42888	27.27448	23.71886	25.52357	24.58287	27.26523	24.18111	26.24970	23.22946	26.60666	26.40275	25.63611	24.09766	25.58489	24.26797	26.51980	23.20606	25.30538	23.63637	25.53705	24.14028	25.46264	-1.661315	0.0000602	0.0005532
GO:0009098	leucine biosynthetic process	biological_process	24.01848	25.66947	23.17564	23.83046	22.64277	25.00892	23.35098	23.88393	24.24233	24.60326	24.03470	24.37107	23.88529	27.16435	25.13814	27.12621	23.96729	24.70726	24.13812	24.76419	24.16288	26.48130	24.02808	24.80091	-1.650992	0.0058779	0.0157246
GO:0019152	acetoin dehydrogenase activity	molecular_function	25.64610	27.28354	24.66079	27.24875	27.94489	27.10264	23.80847	26.28504	24.38650	26.85877	25.13702	26.83937	22.71439	27.70880	20.34970	27.37849	25.41809	27.72103	26.82239	27.46136	23.12647	27.35028	25.19147	27.56753	-1.637433	0.0003310	0.0015878
GO:0002097	tRNA wobble base modification	biological_process	22.97046	24.60152	22.43076	24.16652	22.46802	24.90774	23.12514	24.56525	22.66899	23.83065	23.24343	25.35751	23.00649	24.76562	22.06005	24.13447	23.35788	24.65177	22.58875	24.19980	23.59349	25.45934	23.34927	22.98093	-1.631061	0.0000067	0.0001510
GO:0003951	NAD+ kinase activity	molecular_function	21.35619	22.98540	21.92738	22.74976	21.80253	22.92612	22.11442	21.40238	18.97522	21.85336	21.73494	23.57311	21.42981	24.11020	20.50090	22.15347	20.43444	22.55452	22.14808	23.79475	20.83707	23.37294	20.05550	21.48387	-1.629216	0.0007972	0.0029968
GO:0004155	6,7-dihydropteridine reductase activity	molecular_function	23.05176	24.67600	24.12973	24.63867	24.44527	24.34904	22.49797	24.94139	22.61677	24.59710	22.50152	24.26205	22.52636	24.72115	22.04219	23.58482	22.71931	24.95909	23.44188	24.30928	20.40153	25.63237	22.54224	24.51617	-1.624247	0.0000398	0.0004607
GO:0043531	ADP binding	molecular_function	21.76026	23.38123	21.66085	20.40164	22.17790	22.07306	21.49358	24.42008	22.42123	23.73103	22.06348	23.52536	20.88272	22.94673	21.46787	24.55511	21.81169	22.86523	22.31284	23.33559	21.31199	22.88231	20.72463	22.78927	-1.620974	0.0017643	0.0057223
GO:0002098	tRNA wobble uridine modification	biological_process	22.89167	24.51066	22.34614	24.06599	22.35916	24.80029	23.09237	24.47572	22.56923	23.77075	23.16591	25.30825	22.90163	24.60849	22.01450	24.07349	23.23557	24.57699	22.51236	24.06140	23.53351	25.39144	23.28729	22.77499	-1.618988	0.0000116	0.0002136
GO:0070043	rRNA (guanine-N7-)-methyltransferase activity	molecular_function	19.70349	21.31145	18.18101	20.22865	20.00259	20.82808	20.03456	20.39538	20.41419	20.42315	19.87916	21.48817	18.73480	20.93392	19.65938	20.74183	19.68836	22.94073	19.89424	20.72201	18.82765	22.10341	20.01470	20.75267	-1.607960	0.0001840	0.0010482
GO:0004713	protein tyrosine kinase activity	molecular_function	22.19272	23.78139	23.58646	22.39622	23.44944	25.08196	19.69065	23.97122	20.58843	22.23914	22.24296	23.33781	22.13176	25.05202	20.03102	23.06801	23.40196	22.92065	21.50584	23.46395	19.93330	24.10692	19.10654	22.07193	-1.588667	0.0027666	0.0083459
GO:0052173	response to defenses of other organism involved in symbiotic interaction	biological_process	27.10126	28.67380	28.06258	28.22448	27.60447	28.29689	26.58559	28.65879	26.04302	27.93777	27.24758	29.00287	26.49655	26.99331	26.70305	28.99651	26.84725	28.91252	27.85044	28.77574	26.33633	29.87406	26.82337	27.77861	-1.572547	0.0000595	0.0005505
GO:1990663	dihydroorotate dehydrogenase (fumarate) activity	molecular_function	20.49429	22.06507	20.58678	21.66446	18.00247	19.62093	20.25758	22.96445	18.32304	22.22603	19.90074	23.08796	22.35837	22.69556	19.55526	21.49658	21.84933	21.74214	19.92280	20.74244	19.30354	21.98598	18.11078	21.49829	-1.570780	0.0013039	0.0044857
GO:0043750	phosphatidylinositol alpha-mannosyltransferase activity	molecular_function	19.59024	21.15867	20.05241	20.90992	21.40450	21.74989	19.33952	20.64202	17.73072	20.68555	18.21366	20.39231	19.64779	21.87187	16.19517	20.20917	18.85307	21.38910	20.69022	22.02109	15.33452	19.70773	19.01862	21.33532	-1.568433	0.0012889	0.0044401
GO:0008379	thioredoxin peroxidase activity	molecular_function	23.46181	25.02501	22.76312	24.31278	22.66804	24.31614	22.64515	25.30755	23.37407	26.42878	23.65811	25.06913	24.48336	24.79660	21.68789	24.59193	23.60225	24.06916	23.92980	24.71712	24.35918	25.22731	22.40881	24.73234	-1.563196	0.0000691	0.0005850
GO:0042182	ketone catabolic process	biological_process	24.81122	26.36953	23.64199	26.06274	27.00695	27.06473	22.63318	25.37992	23.44119	25.74469	24.04717	25.80195	22.63464	27.03412	20.97658	26.36629	25.19671	26.58459	25.91989	26.45341	23.46544	26.36042	24.14457	26.29315	-1.558310	0.0002176	0.0011733
GO:0008175	tRNA methyltransferase activity	molecular_function	22.43728	23.99278	23.02615	23.48861	22.87380	23.90317	21.72162	24.17700	23.12096	23.50492	22.32298	24.65968	22.01200	24.44090	22.01374	24.43123	21.75552	23.62716	21.10968	22.94303	21.30186	24.56919	23.46322	22.83598	-1.555502	0.0000318	0.0004042
GO:1990542	mitochondrial transmembrane transport	biological_process	23.63167	25.18478	23.85685	24.83878	23.75773	24.28786	23.34772	25.26877	24.00050	25.20011	22.99673	24.87630	24.35601	25.42771	22.70952	25.57002	23.35217	25.26524	23.53902	25.05444	23.31983	25.66456	23.93740	25.10031	-1.553106	0.0000000	0.0000051
GO:0006839	mitochondrial transport	biological_process	23.63476	25.18478	23.85685	24.83878	23.75773	24.28786	23.34772	25.26877	24.00050	25.20011	22.99673	24.87630	24.35601	25.42771	22.70952	25.57002	23.35217	25.26524	23.53902	25.05444	23.36141	25.66456	23.93740	25.10031	-1.550019	0.0000000	0.0000051
GO:0005388	calcium-transporting ATPase activity	molecular_function	21.52499	23.07391	23.01829	22.80119	22.33231	23.36267	21.95348	22.13015	20.32326	22.60072	20.67143	23.51485	21.80792	23.93907	20.25572	22.94367	20.62023	22.74911	21.11436	22.99964	20.03526	23.59019	21.25044	21.88677	-1.548914	0.0000607	0.0005555
GO:0052255	modulation by organism of defense response of other organism involved in symbiotic interaction	biological_process	26.49710	28.04521	27.47761	27.63952	27.03139	27.71439	26.00063	28.07383	25.29292	27.35281	26.63076	28.41500	25.91159	26.40834	26.11809	28.41154	26.26229	28.32756	27.26548	28.19078	25.53777	29.06803	26.23841	27.19365	-1.548113	0.0000545	0.0005235
GO:0003849	3-deoxy-7-phosphoheptulonate synthase activity	molecular_function	22.65810	24.19199	23.59251	23.73274	23.27957	23.63878	20.82345	23.86571	20.01530	23.81349	22.73368	24.21349	22.77636	24.93006	21.15339	24.95182	22.20626	23.62544	21.51007	23.19858	21.24455	25.06959	24.27193	23.53281	-1.533892	0.0003259	0.0015761
GO:0006449	regulation of translational termination	biological_process	21.89833	23.42866	22.56031	22.94167	22.47538	23.25389	21.07473	22.84124	21.06916	23.07479	21.18300	23.24404	21.97380	24.27231	21.11140	23.22094	22.37442	23.35228	22.39685	23.15132	20.85977	24.10146	22.23764	23.49147	-1.530336	0.0000026	0.0000836
GO:0042779	tRNA 3’-trailer cleavage	biological_process	20.12016	21.64246	21.42822	22.02178	20.84788	21.15383	21.91997	21.17689	18.29628	19.41319	18.21893	21.82526	19.03556	21.28488	19.81977	21.39358	19.36744	23.00934	18.81676	20.74334	18.80163	22.53658	17.41053	19.99065	-1.522300	0.0021217	0.0066515
GO:2001065	mannan binding	molecular_function	23.84294	25.35983	24.45894	24.62602	25.57100	25.42167	23.08970	25.49429	22.51879	24.62512	20.69944	23.74344	24.30030	26.39341	21.83316	25.57081	23.84076	24.93638	24.38458	25.66931	23.03874	25.47853	22.52311	25.43691	-1.516892	0.0005510	0.0022871
GO:0098800	inner mitochondrial membrane protein complex	cellular_component	23.13292	24.64941	23.15201	23.10266	23.76179	24.23122	20.81050	24.75546	23.42400	24.78941	22.61729	23.74653	24.25162	25.16128	21.95759	25.47936	22.55865	23.99736	23.48414	24.61754	22.82222	25.47677	23.05827	23.92179	-1.516487	0.0003002	0.0014971
GO:0000774	adenyl-nucleotide exchange factor activity	molecular_function	24.32629	25.84120	24.30784	25.53110	23.55729	24.20699	24.30697	27.23919	24.64685	25.58826	24.83861	25.46078	24.56673	26.16390	24.24801	25.65877	24.38738	25.56842	24.03469	25.60910	24.26104	25.91397	24.03906	25.45626	-1.514911	0.0000110	0.0002061
GO:0000716	transcription-coupled nucleotide-excision repair, DNA damage recognition	biological_process	19.67429	21.18911	14.55058	17.78929	18.71877	19.31997	16.07805	20.40129	NA	22.06774	20.24497	20.63499	20.27340	22.83731	21.67497	21.64916	19.80240	18.90060	18.67157	21.16223	16.12685	20.07316	19.14663	21.64856	-1.514821	0.0220387	0.0453796
GO:0048584	positive regulation of response to stimulus	biological_process	25.50851	27.01898	26.48026	26.63976	26.06818	26.72627	25.00239	27.07383	24.25316	26.35325	25.67559	27.43257	24.92964	25.42985	25.13803	27.42106	25.32822	27.33272	26.26712	27.19078	24.35917	27.88514	25.27542	26.20223	-1.510477	0.0000595	0.0005505
GO:0004721	phosphoprotein phosphatase activity	molecular_function	23.25744	24.76547	24.48230	25.28672	23.70338	23.89670	21.76429	25.27645	21.81177	24.08275	23.09528	25.42747	23.55340	24.36440	22.07889	23.95604	23.80509	25.25819	23.29974	24.65456	22.87043	25.05595	22.85917	23.77376	-1.508034	0.0000802	0.0006316
GO:0019941	modification-dependent protein catabolic process	biological_process	23.12691	24.62890	23.38153	24.40070	21.76769	23.19608	21.62623	25.58532	22.33095	21.65076	21.56643	23.53823	25.02915	24.79058	22.74660	25.84007	23.03436	24.45457	22.59893	25.00226	23.39610	22.97996	22.81593	25.01265	-1.501990	0.0064976	0.0169942
GO:0000721	(R,R)-butanediol dehydrogenase activity	molecular_function	24.12793	25.62915	23.41732	25.57009	26.48238	25.89113	22.67214	24.84338	22.95280	25.16854	23.42325	24.33650	22.46395	25.97558	22.07362	26.31059	23.21454	25.38309	25.00064	25.61675	21.64213	26.29502	23.72641	25.35985	-1.501219	0.0001127	0.0007546
GO:0003713	transcription coactivator activity	molecular_function	21.37576	22.87232	22.33908	23.03456	20.69260	19.83074	21.22634	22.72743	19.45588	23.13777	21.92942	23.47153	21.91764	24.09718	20.85151	22.66318	21.21333	22.96240	21.83789	22.56481	20.49815	21.57101	21.10200	22.26756	-1.496560	0.0033619	0.0099108
GO:0052587	diacetyl reductase ((R)-acetoin forming) activity	molecular_function	23.69208	25.18671	23.04445	25.28250	25.79670	24.15446	21.93671	24.28921	22.67273	25.03562	23.64585	25.16554	20.32317	25.37179	16.84514	24.49037	23.73375	25.99750	24.77800	25.54539	19.13814	23.91874	23.69600	26.04582	-1.494633	0.0036441	0.0105706
GO:0009020	tRNA (guanosine-2’-O-)-methyltransferase activity	molecular_function	20.19132	21.67696	20.63128	21.48542	20.64790	20.94341	19.16318	22.16693	21.36004	21.52644	20.13486	22.32937	19.77997	21.70527	19.91588	21.12044	18.85419	21.86107	18.54439	21.15495	17.35690	22.21337	21.28734	21.08433	-1.485635	0.0001984	0.0011030
GO:0000154	rRNA modification	biological_process	23.62034	25.09534	24.55958	24.50643	23.88063	24.77583	22.54800	24.84866	22.66357	24.82171	23.56107	25.21086	24.58130	25.93408	23.14749	24.80488	23.41027	25.26224	23.79496	24.72549	22.38049	25.86922	23.38674	24.27901	-1.475002	0.0000143	0.0002487
GO:0000921	septin ring assembly	biological_process	23.40079	24.86922	24.35613	24.72875	25.30125	24.93383	20.97731	24.92408	21.04959	24.44374	23.00759	25.14275	23.96580	25.11840	21.51548	23.59505	22.49801	24.74630	23.37255	25.07689	21.46285	25.18823	22.79542	25.04844	-1.468431	0.0001906	0.0010723
GO:0005940	septin ring	cellular_component	23.40079	24.86922	24.35613	24.72875	25.30125	24.93383	20.97731	24.92408	21.04959	24.44374	23.00759	25.14275	23.96580	25.11840	21.51548	23.59505	22.49801	24.74630	23.37255	25.07689	21.46285	25.18823	22.79542	25.04844	-1.468431	0.0001906	0.0010723
GO:0051707	response to other organism	biological_process	27.96019	29.40975	28.58765	28.80939	29.18453	29.50607	27.09520	29.21480	26.60617	28.46146	27.85376	29.63005	28.03248	28.90124	27.21277	29.53595	27.41517	29.43402	28.81841	29.80537	26.79682	30.38387	27.35601	28.72769	-1.449560	0.0000445	0.0004795
GO:0003688	DNA replication origin binding	molecular_function	21.16776	22.61657	21.75142	22.29212	22.15815	22.39365	20.49478	22.67407	18.70817	21.14338	21.34599	23.82433	20.76865	22.95503	19.57041	21.59348	22.31168	22.48631	20.92843	22.18043	20.66694	23.13052	20.69718	22.28871	-1.448807	0.0005373	0.0022467
GO:0009229	thiamine diphosphate biosynthetic process	biological_process	22.02249	23.46744	21.74665	23.20160	21.44306	24.02240	22.36071	23.13581	21.01687	22.59077	22.80187	23.55335	21.54387	24.61220	22.07936	23.09408	22.07226	23.33299	21.82220	22.56639	21.86285	24.10382	22.57592	21.79862	-1.444948	0.0001478	0.0008947
GO:0060590	ATPase regulator activity	molecular_function	24.40534	25.84900	24.30784	25.53110	23.55729	24.20699	24.34419	27.23944	24.79458	25.63320	25.17377	25.51030	24.56673	26.16390	24.25881	25.65909	24.38738	25.56842	24.06743	25.60910	24.31744	25.91397	24.07743	25.46678	-1.443666	0.0000285	0.0003940
GO:0016426	tRNA (adenine) methyltransferase activity	molecular_function	19.20589	20.64898	20.21815	19.88003	20.88589	20.08276	18.45192	19.86139	NA	18.71628	18.61171	21.72336	18.56851	21.31062	14.88494	20.73242	16.93570	19.65840	17.93527	18.42143	18.31741	22.32451	19.94431	18.57859	-1.443091	0.0223832	0.0459152
GO:0019277	UDP-N-acetylgalactosamine biosynthetic process	biological_process	20.76976	22.21122	20.24009	19.94302	20.63826	20.80886	20.07879	22.11682	20.08284	21.78181	21.38237	22.54465	21.06016	22.07342	18.91834	21.22044	22.27563	21.57549	20.59755	20.66507	20.81500	24.41024	19.31717	21.16735	-1.441459	0.0174636	0.0376997
GO:0004714	transmembrane receptor protein tyrosine kinase activity	molecular_function	20.58495	22.02594	21.90482	20.66767	21.65751	21.44095	16.00025	21.92571	18.81618	20.56410	21.03396	22.05573	19.55937	23.62603	19.11907	21.61783	22.32087	21.46634	16.34450	19.12884	18.80354	23.42805	18.04730	20.65142	-1.440990	0.0119661	0.0278005
GO:0009982	pseudouridine synthase activity	molecular_function	22.92011	24.36009	23.98991	24.69543	22.46941	24.12003	23.33408	24.39474	20.69156	23.67845	23.79349	24.43547	23.53962	24.35734	22.15128	23.97519	22.40783	24.59473	22.30067	24.44337	21.53669	24.92875	22.81997	23.86011	-1.439977	0.0000410	0.0004667
GO:0004412	homoserine dehydrogenase activity	molecular_function	23.89619	25.33098	24.64263	24.70640	24.45880	24.72801	23.40842	24.62343	22.59891	24.67767	23.59676	25.75711	24.79295	26.18929	22.84222	25.34970	24.45152	24.82164	23.40147	25.05111	23.54119	26.48726	23.17893	24.38812	-1.434790	0.0001477	0.0008947
GO:0036370	D-alanyl carrier activity	molecular_function	23.66943	25.10376	25.06249	25.81948	24.20328	24.64411	24.36764	25.56315	21.25967	24.81311	22.25013	25.90268	22.69792	24.73084	23.35252	24.98776	23.67769	24.85861	22.23932	24.31408	20.61994	24.29297	24.61869	25.11952	-1.434328	0.0006057	0.0024529
GO:0051239	regulation of multicellular organismal process	biological_process	29.00531	30.43067	29.88433	30.40008	30.27079	30.28008	28.00596	30.74869	28.33801	30.76827	28.37408	29.58593	29.10436	30.54058	28.21322	30.62971	28.54676	30.72094	29.53277	30.49125	27.31397	29.79268	28.77748	30.30659	-1.425367	0.0000153	0.0002644
GO:0003856	3-dehydroquinate synthase activity	molecular_function	21.23133	22.65468	20.94681	22.89370	18.59639	20.63965	20.46197	21.92210	17.47516	21.62625	21.31213	23.28367	22.00526	23.90608	22.83406	22.86876	21.87894	22.83554	20.55611	21.45646	20.83306	22.85057	20.49688	22.09488	-1.423353	0.0044278	0.0123688
GO:0070051	fibrinogen binding	molecular_function	26.03694	27.44698	26.62965	26.83604	27.36339	27.68382	25.12509	27.30191	24.45601	26.50337	25.77580	27.60499	26.21728	27.16196	25.25754	27.60799	25.42450	27.50030	26.96862	27.96773	24.42368	28.08056	25.47986	26.85679	-1.410040	0.0000688	0.0005850
GO:0060589	nucleoside-triphosphatase regulator activity	molecular_function	24.47584	25.88500	24.62666	25.55922	23.62274	24.32399	24.36277	27.24341	24.79458	25.64373	25.20330	25.56330	24.71263	26.25362	24.26421	25.66252	24.40609	25.60635	24.11480	25.67925	24.41725	25.96762	24.10829	25.47850	-1.409155	0.0000294	0.0003990
GO:0030247	polysaccharide binding	molecular_function	23.96917	25.37706	24.45894	24.62602	25.57605	25.42229	23.08970	25.49429	22.82084	24.62512	21.02137	23.75032	24.44346	26.41630	22.58958	25.58737	24.08946	24.95451	24.38458	25.68748	23.05280	25.55442	23.45774	25.43727	-1.407884	0.0007786	0.0029393
GO:0048544	recognition of pollen	biological_process	18.30119	19.70900	18.93356	19.17702	18.91110	19.98952	NA	NA	NA	19.17569	NA	19.88128	18.62105	NA	NA	NA	16.51284	19.83719	NA	NA	NA	NA	16.92794	19.95152	-1.407814	0.0083792	0.0209519
GO:0052915	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	molecular_function	19.15077	20.55623	19.98837	21.29473	NA	19.14804	18.26089	20.44581	19.99180	19.33472	19.28334	21.84920	18.11121	20.92118	19.51256	20.82875	18.79284	20.27792	18.59397	18.84690	18.21552	20.02394	19.19505	20.29040	-1.405458	0.0019125	0.0060801
GO:0016435	rRNA (guanine) methyltransferase activity	molecular_function	20.83315	22.23340	20.94091	21.89480	20.16722	21.72913	20.44215	21.59121	21.23082	21.17546	20.88438	23.04478	19.56771	22.53004	20.95238	22.33166	20.66777	23.19249	21.29398	21.11516	20.76812	22.47477	21.36914	21.80409	-1.400253	0.0000641	0.0005730
GO:0103025	alpha-amylase activity (releasing maltohexaose)	molecular_function	20.06512	21.45899	22.49663	23.04523	20.90184	22.40226	NA	17.79721	17.35411	21.03784	19.34934	21.54945	17.52288	22.23024	19.21539	19.44017	18.79370	21.47262	17.50697	18.63629	16.87951	20.79776	19.41530	20.29792	-1.393862	0.0216927	0.0448030
GO:0015103	inorganic anion transmembrane transporter activity	molecular_function	24.52685	25.91935	24.37234	25.93535	24.96988	25.60862	24.59706	25.96879	23.78879	26.42566	24.09094	25.78097	25.88873	25.96605	24.19995	26.31385	24.94755	26.00010	23.33245	25.47610	23.48172	26.09198	24.06465	25.06015	-1.392499	0.0000056	0.0001352
GO:0004715	non-membrane spanning protein tyrosine kinase activity	molecular_function	21.42215	22.80765	22.98830	21.40258	22.59161	24.12442	19.19087	23.26743	19.58843	21.23914	21.42547	22.57365	21.40243	23.84575	18.86632	22.04094	22.40327	21.93714	21.22021	23.11862	19.05235	22.55524	18.10654	21.07193	-1.385494	0.0061084	0.0162293
GO:0004399	histidinol dehydrogenase activity	molecular_function	19.12456	20.50717	16.32321	20.42688	NA	NA	18.22320	20.18668	18.95388	19.92233	16.98281	20.93593	21.39745	18.86679	17.63769	22.28280	NA	18.09705	13.19745	NA	NA	20.31522	NA	19.29735	-1.382610	0.0195356	0.0412570
GO:0014070	response to organic cyclic compound	biological_process	21.31718	22.69865	19.96605	21.81817	19.65066	22.46177	19.95649	22.45761	21.14164	22.36866	21.92424	21.17419	19.87900	22.60804	19.79514	23.65812	23.30696	23.17055	20.36344	19.79201	21.72056	24.18418	21.26900	21.42899	-1.381469	0.0090219	0.0222721
GO:0030234	enzyme regulator activity	molecular_function	26.60894	27.98706	24.88349	26.29249	24.48436	28.66249	25.94837	27.30647	28.23944	27.15922	27.02462	25.64157	27.22958	28.58758	26.47440	29.03245	25.63758	27.93637	25.64341	26.73191	26.06118	29.04745	26.93179	27.38719	-1.378119	0.0086337	0.0214895
GO:0051241	negative regulation of multicellular organismal process	biological_process	26.86457	28.24123	27.80658	28.29624	28.21752	28.19697	25.92088	28.50120	26.12046	28.33347	26.26138	27.46880	27.02760	28.35252	26.16042	28.49392	26.38205	28.68156	27.25301	28.33604	24.44371	27.55111	26.55038	27.96579	-1.376667	0.0000695	0.0005850
GO:0004517	nitric-oxide synthase activity	molecular_function	18.62778	20.00325	20.33944	19.69326	19.52393	18.15480	NA	NA	NA	NA	17.93975	20.07393	18.20258	20.12565	18.23829	21.25904	17.12057	19.15731	16.16131	18.34890	16.32020	20.60249	NA	NA	-1.375471	0.0190230	0.0403311
GO:0050818	regulation of coagulation	biological_process	28.44733	29.82140	29.39136	29.88055	29.80248	29.78194	27.50549	30.08585	27.70542	29.91843	27.82237	28.96825	28.60881	29.93694	27.74418	30.07816	27.96277	30.26563	28.83797	29.92101	26.02867	29.13550	28.13535	29.55076	-1.374068	0.0000772	0.0006205
GO:0030193	regulation of blood coagulation	biological_process	27.86213	29.23612	28.80631	29.29526	29.21752	29.19697	26.92035	29.50073	27.12046	29.33347	27.23677	28.38047	28.02383	29.35178	27.15861	29.49284	27.37568	29.68022	28.25301	29.33604	25.44371	28.55024	27.55038	28.96579	-1.373983	0.0000774	0.0006205
GO:0030195	negative regulation of blood coagulation	biological_process	26.86213	28.23612	27.80631	28.29526	28.21752	28.19697	25.92035	28.50073	26.12046	28.33347	26.23677	27.38047	27.02383	28.35178	26.15861	28.49284	26.37568	28.68022	27.25301	28.33604	24.44371	27.55024	26.55038	27.96579	-1.373983	0.0000774	0.0006205
GO:0061041	regulation of wound healing	biological_process	28.44710	29.82108	29.39127	29.88022	29.80248	29.78194	27.50532	30.08569	27.70542	29.91843	27.82173	28.96543	28.60879	29.93674	27.74358	30.07780	27.96065	30.26519	28.83797	29.92101	26.02867	29.13521	28.13535	29.55076	-1.373983	0.0000774	0.0006205
GO:1900046	regulation of hemostasis	biological_process	28.44710	29.82108	29.39127	29.88022	29.80248	29.78194	27.50532	30.08569	27.70542	29.91843	27.82173	28.96543	28.60879	29.93674	27.74358	30.07780	27.96065	30.26519	28.83797	29.92101	26.02867	29.13521	28.13535	29.55076	-1.373983	0.0000774	0.0006205
GO:1903034	regulation of response to wounding	biological_process	28.86213	30.23612	29.80631	30.29526	30.21752	30.19697	27.92035	30.50073	28.12046	30.33347	28.23677	29.38047	29.02383	30.35178	28.15861	30.49284	28.37568	30.68022	29.25301	30.33604	26.44371	29.55024	28.55038	29.96579	-1.373983	0.0000774	0.0006205
GO:0051919	positive regulation of fibrinolysis	biological_process	26.86213	28.23591	27.80631	28.29526	28.21752	28.19697	25.92035	28.49883	26.12046	28.33347	26.23677	27.38047	27.02383	28.35178	26.15861	28.49284	26.37568	28.68022	27.25301	28.33604	24.44371	27.55024	26.55038	27.96579	-1.373776	0.0000775	0.0006205
GO:0102499	SHG alpha-glucan phosphorylase activity	molecular_function	24.78783	26.16073	25.20663	25.83523	25.28479	24.63427	24.04673	25.66593	24.17425	25.90050	24.48317	24.94768	24.68876	26.87973	24.34354	26.90899	24.49230	26.10310	24.58239	25.93344	25.10630	26.89008	25.45940	26.27185	-1.372899	0.0001111	0.0007546
GO:0000101	sulfur amino acid transport	biological_process	21.64013	23.01080	21.47744	23.14987	18.08491	21.34027	20.89936	23.20064	21.96609	22.54819	21.11557	23.70097	22.27813	23.29434	20.66975	22.79244	22.81512	22.93501	21.25479	22.75320	22.59990	23.39727	20.45368	22.91490	-1.370677	0.0010023	0.0036178
GO:0043225	ATPase-coupled anion transmembrane transporter activity	molecular_function	23.74613	25.10801	23.48197	25.25851	24.06253	24.86955	24.27551	25.49543	22.96003	25.08054	23.32129	25.24822	25.46022	25.23648	22.83583	24.74386	23.61687	25.27482	22.60396	24.86022	22.16659	25.37423	23.10000	24.40345	-1.361880	0.0000169	0.0002798
GO:0009378	four-way junction helicase activity	molecular_function	20.23815	21.59956	19.47186	20.15960	21.46443	22.94829	19.07218	20.36689	19.66901	20.90471	20.98663	21.87390	18.34916	22.45299	18.25854	20.66658	20.43381	21.22465	19.75110	21.03551	19.20430	20.69530	21.50242	22.20303	-1.361408	0.0029735	0.0088910
GO:0052654	L-leucine transaminase activity	molecular_function	23.85758	25.21823	22.54901	23.18102	22.27413	24.45834	23.43565	24.64752	24.05317	25.48843	23.83391	24.37101	23.73163	26.05637	25.22513	25.97607	23.29869	25.05268	23.97558	24.63016	23.70688	25.36683	24.15114	25.88428	-1.360656	0.0010757	0.0038119
GO:0015416	ATPase-coupled organic phosphonate transmembrane transporter activity	molecular_function	22.73616	24.09461	21.85396	24.08508	22.68844	23.70402	23.91090	24.86014	21.19083	24.30230	21.77573	24.45108	24.85819	23.92209	21.48675	23.28844	21.96237	24.08747	21.58083	23.86775	20.65288	24.35826	21.14733	23.35613	-1.358448	0.0001235	0.0007915
GO:0080134	regulation of response to stress	biological_process	29.04217	30.40060	29.96030	30.41324	30.31244	30.33737	28.11255	30.63786	28.26729	30.42452	28.66502	29.78453	29.15319	30.41680	28.41251	30.66513	28.56770	30.82010	29.45348	30.49294	27.06645	30.03407	28.69974	30.06858	-1.358429	0.0000218	0.0003347
GO:0050878	regulation of body fluid levels	biological_process	28.48058	29.83337	29.40398	29.88750	29.81385	29.79454	27.51540	30.09364	27.74020	29.92126	27.98667	29.03169	28.64265	29.95041	27.81084	30.08815	27.98353	30.27234	28.85994	29.92361	26.25906	29.17551	28.14338	29.55138	-1.352786	0.0000587	0.0005499
GO:0004084	branched-chain-amino-acid transaminase activity	molecular_function	25.44136	26.79227	24.11428	24.65216	23.86871	26.06864	25.02062	26.18505	25.63813	27.05992	25.41851	25.93052	25.31307	27.64134	26.81009	27.55910	24.88026	26.61844	25.56054	26.20890	25.29184	26.95179	25.73415	27.45518	-1.350903	0.0013909	0.0047433
GO:0006813	potassium ion transport	biological_process	22.16556	23.51386	21.25305	23.80474	22.84421	21.81964	21.76314	23.25278	22.92042	22.70199	22.53721	23.98912	22.56945	23.73556	20.21853	22.17283	21.90301	24.54704	21.37286	23.16220	21.23871	23.64076	22.85346	23.76521	-1.348299	0.0010874	0.0038433
GO:0005315	inorganic phosphate transmembrane transporter activity	molecular_function	21.84008	23.18825	22.65082	23.17529	22.36144	23.38250	22.27928	23.67283	19.47861	22.79366	23.18170	24.09240	21.47097	22.77981	21.49379	22.45028	22.20224	23.42305	20.39402	22.66024	19.72745	23.32826	20.01044	22.21191	-1.348165	0.0006659	0.0026498
GO:0052655	L-valine transaminase activity	molecular_function	23.85654	25.20449	22.54901	23.18102	22.27413	24.45834	23.43565	24.63910	24.05317	25.44744	23.83144	24.35304	23.73015	26.04335	25.22407	25.97073	23.29869	25.05268	23.97300	24.59949	23.70504	25.35341	24.15079	25.87227	-1.347948	0.0011421	0.0040055
GO:0048583	regulation of response to stimulus	biological_process	30.22126	31.56444	31.12229	31.57391	31.47927	31.50075	29.27061	31.79754	29.46107	31.58767	29.89067	30.95825	30.34712	31.58932	29.61092	31.82407	29.74647	31.97892	30.61990	31.65168	28.34346	31.21547	29.86617	31.23028	-1.343179	0.0000194	0.0003043
GO:0006400	tRNA modification	biological_process	25.96893	27.30867	26.35774	27.05206	26.11812	27.62249	25.53441	27.07001	25.55876	26.51897	26.11502	27.73877	26.16619	27.58800	25.10909	26.70241	26.49486	27.60752	25.86090	27.31219	25.67063	27.85985	26.11203	26.51823	-1.339731	0.0000013	0.0000586
GO:0008990	rRNA (guanine-N2-)-methyltransferase activity	molecular_function	19.74179	21.08098	20.63753	21.31620	16.04150	20.14804	18.41958	20.76361	20.02071	19.87623	19.88957	22.38117	18.35152	21.86529	19.98217	21.68430	18.94336	20.52042	20.23476	19.04741	20.15217	20.33521	20.29492	20.82948	-1.339193	0.0093234	0.0228503
GO:0008033	tRNA processing	biological_process	26.83441	28.17136	27.35866	27.85869	26.78143	28.35342	26.42658	27.84027	26.09987	27.61617	26.80403	28.54145	27.59699	28.66994	26.51191	27.80355	27.11498	28.35116	26.78452	28.05082	26.18733	28.77094	26.75816	27.27387	-1.336950	0.0000015	0.0000594
GO:0015114	phosphate ion transmembrane transporter activity	molecular_function	22.12584	23.45708	22.49402	23.79091	23.28957	24.14718	20.73424	23.52165	21.61027	22.82169	19.95398	23.40624	21.67957	23.48994	19.97577	23.54596	23.84270	23.65496	20.79387	22.88244	22.05563	23.58932	21.31533	22.36879	-1.331240	0.0003124	0.0015271
GO:0017000	antibiotic biosynthetic process	biological_process	24.22849	25.55831	25.31094	26.08361	23.78303	24.06152	22.55843	26.42810	22.35612	25.44617	22.40018	25.75504	23.43006	25.22864	23.02912	24.83155	26.67392	26.13732	22.46959	25.45835	21.07643	25.22046	22.95553	25.02227	-1.329821	0.0004031	0.0018151
GO:0032101	regulation of response to external stimulus	biological_process	28.51282	29.84124	29.41623	29.89113	29.82484	29.80516	27.52423	30.09845	27.77345	29.92190	28.13402	29.08732	28.67540	29.96060	27.87444	30.09351	28.00636	30.27254	28.88128	29.92458	26.45122	29.19803	28.15138	29.55201	-1.328421	0.0000491	0.0004999
GO:0004614	phosphoglucomutase activity	molecular_function	25.88125	27.20896	26.51131	26.20782	26.71366	26.98900	24.79488	27.53234	25.63583	27.12224	25.21564	26.64159	26.63386	27.96453	25.64977	27.59999	25.79675	26.87043	26.08092	27.33360	24.60473	27.16705	25.33721	27.09173	-1.327709	0.0000246	0.0003640
GO:0009423	chorismate biosynthetic process	biological_process	23.82187	25.14512	24.37474	24.95743	23.95691	24.47652	22.47104	24.85696	21.61055	24.45060	24.22288	25.56399	23.97131	25.84973	23.64319	25.55272	23.96460	24.99339	23.55272	24.14491	23.11618	25.78589	24.79774	24.82976	-1.323248	0.0002643	0.0013556
GO:0098754	detoxification	biological_process	24.75486	26.07512	24.46664	26.02783	24.59448	25.56881	23.96936	26.86012	24.62439	25.87261	24.52315	26.88991	26.35955	26.11247	24.37286	25.76769	24.39806	25.73099	23.28959	25.31692	24.98599	26.33536	24.46067	25.25416	-1.320258	0.0000498	0.0004999
GO:0004644	phosphoribosylglycinamide formyltransferase activity	molecular_function	21.51604	22.83355	20.24592	22.27903	21.12579	23.06243	19.66731	22.46566	19.14978	22.45481	23.26216	22.40948	21.73665	24.28380	20.84536	22.79068	19.47882	22.27190	21.94094	23.55833	20.86588	21.37339	22.50118	21.71631	-1.317508	0.0022074	0.0068963
GO:0004160	dihydroxy-acid dehydratase activity	molecular_function	24.48965	25.80605	26.89109	24.09967	24.55605	24.75352	22.57036	27.00892	22.09814	25.26710	23.90069	24.97935	24.82669	26.34856	23.23416	26.35222	23.66733	26.26687	23.65022	24.97468	22.66024	25.89768	23.37564	25.36533	-1.316398	0.0011392	0.0040006
GO:0048585	negative regulation of response to stimulus	biological_process	27.96312	29.27469	28.84359	29.31159	29.25093	29.23166	26.94864	29.51982	27.24201	29.33867	27.68652	28.55965	28.12316	29.38743	27.36095	29.51536	27.43839	29.69119	28.31749	29.34139	26.11053	28.78182	27.57436	28.96767	-1.311572	0.0000311	0.0004042
GO:0006734	NADH metabolic process	biological_process	26.14354	27.45181	26.78089	26.89717	26.81071	27.63887	25.13762	27.00239	24.99342	27.30056	25.17918	26.63682	27.00617	28.25241	26.37880	27.13078	26.63253	27.37778	26.07080	27.65022	25.03405	27.73860	25.36335	27.61510	-1.308272	0.0000497	0.0004999
GO:0032977	membrane insertase activity	molecular_function	21.90068	23.20865	20.99024	22.42795	22.43822	22.69251	20.20388	22.56871	19.97364	22.25016	23.14705	24.08547	22.38052	23.82640	21.65923	21.65837	20.46700	22.94238	21.82322	21.91149	22.38330	24.76285	22.06022	22.64162	-1.307973	0.0064652	0.0169378
GO:0032102	negative regulation of response to external stimulus	biological_process	26.95924	28.26614	27.84359	28.31159	28.25093	28.23166	25.94864	28.51982	26.22134	28.33867	26.68304	27.55965	27.12262	28.38743	26.34989	28.51534	26.43839	28.69119	27.31749	28.34139	25.03868	27.64348	26.57436	27.96767	-1.306898	0.0000416	0.0004667
GO:0030430	host cell cytoplasm	cellular_component	23.83950	25.13526	22.60871	24.64140	22.09529	23.73262	22.33572	25.53645	23.72565	25.66119	24.29262	25.34895	21.85279	25.09090	24.71610	24.42955	24.44689	26.18238	24.65876	24.60305	24.74537	25.49780	22.44225	23.68169	-1.295760	0.0023137	0.0072117
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	biological_process	27.56154	28.85647	28.30436	28.45650	27.66783	28.34873	27.38605	28.87988	26.91471	28.48454	27.71110	29.18427	26.73203	27.37057	27.42024	29.23496	27.72776	29.21580	27.95650	28.80655	26.97189	29.79246	27.62615	28.29070	-1.294931	0.0000496	0.0004999
GO:0008830	dTDP-4-dehydrorhamnose 3,5-epimerase activity	molecular_function	23.13790	24.42863	24.44365	24.09951	24.17402	24.52758	21.86995	24.46508	22.27797	24.04237	23.11200	23.97752	22.91676	24.97154	22.26675	25.06399	22.70146	24.79483	23.71974	24.48192	20.60574	23.75386	22.65507	23.80176	-1.290728	0.0002731	0.0013898
GO:0007010	cytoskeleton organization	biological_process	24.12931	25.41778	24.65232	24.83876	25.48343	25.14493	21.79018	25.09509	21.81978	26.18690	24.80240	25.80968	24.97996	26.08115	23.43386	24.05187	23.35670	25.08734	23.64997	25.08403	23.56417	25.59650	23.42425	25.40996	-1.288474	0.0008735	0.0032347
GO:0044455	mitochondrial membrane part	cellular_component	23.41335	24.70160	23.37688	23.21448	24.01842	24.43376	20.95620	24.75546	23.52850	24.79335	22.61729	23.77677	24.25162	25.16128	22.40995	25.47936	23.10622	24.12725	23.96238	24.63320	23.27700	25.59901	23.67026	23.97554	-1.288247	0.0012487	0.0043124
GO:0046349	amino sugar biosynthetic process	biological_process	22.59334	23.87907	23.06093	23.10674	22.97631	23.87544	22.00232	22.96835	21.81057	23.40722	23.02894	24.61227	22.43559	23.48316	21.44053	22.64611	23.09201	23.87355	22.93175	23.85985	21.88186	25.35117	22.70629	23.04027	-1.285733	0.0008649	0.0032071
GO:0009451	RNA modification	biological_process	26.74722	28.03197	27.30733	27.68420	26.81366	28.15945	26.26013	27.77973	26.16380	27.38084	26.95350	28.41017	27.19958	28.51140	25.88459	27.53833	27.16597	28.28026	26.65043	27.94035	26.24271	28.66496	26.81617	27.20631	-1.284743	0.0000041	0.0001146
GO:0044003	modification by symbiont of host morphology or physiology	biological_process	26.01296	27.29547	26.63735	26.79331	26.01661	26.74844	25.85755	27.32251	25.30524	27.13145	25.95030	27.55459	25.26114	25.88432	25.59837	27.61397	26.27026	27.58407	26.48849	27.25178	26.18299	28.26838	25.91349	26.82923	-1.282516	0.0000309	0.0004042
GO:0006107	oxaloacetate metabolic process	biological_process	24.35735	25.63883	24.37880	24.76012	24.34720	25.66991	23.40283	24.87153	24.77925	24.15988	24.51626	25.93630	24.24353	26.71233	24.57219	26.11192	23.38830	25.26740	23.94881	25.40467	24.09167	26.24236	25.23637	24.95813	-1.281480	0.0003848	0.0017578
GO:0051260	protein homooligomerization	biological_process	27.46373	28.73997	28.36070	28.26913	28.60359	28.83943	26.26085	28.86477	25.98923	28.72054	26.90983	28.31343	28.20438	28.94760	26.76550	29.00846	27.65440	29.01283	27.67709	28.87508	25.75013	28.56142	26.64249	28.48281	-1.276240	0.0000653	0.0005776
GO:0016433	rRNA (adenine) methyltransferase activity	molecular_function	22.78188	24.05810	23.93732	22.73781	23.09898	24.01907	21.78194	23.88908	21.18284	23.57500	22.83586	24.01487	23.55923	24.69084	21.11017	23.48581	22.89891	24.26947	23.38687	23.95353	21.54822	24.99891	22.04448	23.77237	-1.276219	0.0004901	0.0021110
GO:0008184	glycogen phosphorylase activity	molecular_function	24.95954	26.23233	25.29011	25.86769	25.57079	24.89589	24.20558	25.71469	24.35175	25.97185	24.65669	25.07827	24.95865	26.96644	24.49514	26.92692	24.60724	26.15151	24.80451	26.09980	25.13310	26.91912	25.65701	26.36385	-1.272792	0.0001396	0.0008585
GO:0008649	rRNA methyltransferase activity	molecular_function	23.72501	24.99637	24.41519	23.78063	23.62091	24.78960	22.68428	24.44602	22.56113	24.50600	24.02840	25.19311	24.03698	25.63498	22.71958	25.05518	24.83548	25.31775	23.92006	24.86797	22.81867	25.83801	23.23632	24.27681	-1.271366	0.0002075	0.0011327
GO:0031167	rRNA methylation	biological_process	23.46844	24.73284	24.31417	23.95948	23.79830	24.66134	22.42621	24.37788	22.54081	24.46158	23.43196	24.75581	24.40778	25.68359	23.05605	24.60227	23.24736	24.86028	23.63254	24.35395	22.27240	25.38910	23.27694	23.87827	-1.264402	0.0000854	0.0006476
GO:0002949	tRNA threonylcarbamoyladenosine modification	biological_process	21.93212	23.19188	21.75490	22.66567	20.64126	23.11452	22.10881	23.50202	22.18334	22.24736	22.00453	24.04500	22.10975	23.09785	21.98829	22.66095	21.12289	23.27329	20.47006	22.21628	22.15328	24.24763	22.97819	22.24185	-1.259758	0.0006020	0.0024459
GO:0042256	mature ribosome assembly	biological_process	21.32003	22.57872	22.58196	23.26786	21.42125	22.00673	19.19248	23.18544	20.57834	22.62674	20.48100	22.79096	19.97086	21.40853	22.71814	22.30175	21.05873	23.08457	20.92144	22.09012	21.22389	22.32321	20.55084	22.18246	-1.258688	0.0004081	0.0018303
GO:0090071	negative regulation of ribosome biogenesis	biological_process	21.26583	22.52375	22.58196	23.26786	21.42125	22.00673	19.19248	23.18544	20.57834	22.62674	20.48100	22.79096	19.78253	20.80304	22.71814	22.30175	21.05873	23.08457	20.92144	22.09012	20.52903	21.78967	20.55084	22.18246	-1.257920	0.0010206	0.0036648
GO:0008173	RNA methyltransferase activity	molecular_function	24.52495	25.77969	25.05731	25.04692	24.56016	25.59286	23.76303	25.54860	24.28107	25.28555	24.81367	26.17624	24.48736	26.29433	23.86796	25.88939	25.20355	25.89881	24.29443	25.35032	23.72987	26.56153	24.83009	25.00808	-1.254742	0.0000131	0.0002367
GO:0005681	spliceosomal complex	cellular_component	22.61795	23.86363	NA	24.37607	20.55846	22.76292	23.56311	23.57894	22.94817	23.22554	21.53516	24.15201	21.68821	23.95999	22.64404	23.33995	22.39307	24.61664	NA	NA	22.69832	23.04555	23.33973	24.35452	-1.245675	0.0017714	0.0057323
GO:0005618	cell wall	cellular_component	28.80908	30.05417	29.23939	29.58806	30.11123	30.26496	27.82320	29.81322	27.76547	29.84484	28.58316	29.52678	29.33688	30.51711	28.06201	30.47491	28.37651	30.17123	29.12747	29.99807	27.80235	29.95705	28.51979	30.07649	-1.245095	0.0000159	0.0002688
GO:0030312	external encapsulating structure	cellular_component	28.81327	30.05526	29.23939	29.58806	30.11776	30.26872	27.82320	29.81322	27.76703	29.84484	28.58451	29.52826	29.33688	30.51711	28.06201	30.47491	28.37651	30.17123	29.12925	29.99825	27.85354	29.96394	28.51979	30.07649	-1.241994	0.0000157	0.0002660
GO:0019200	carbohydrate kinase activity	molecular_function	26.58725	27.82866	26.78924	27.25974	27.38536	27.73476	26.56247	27.91872	25.99576	27.23749	26.32312	27.49516	26.72134	28.58016	25.86580	28.02088	26.77018	27.87456	26.77017	27.93167	26.17986	27.97067	26.44053	27.56200	-1.241416	0.0000006	0.0000410
GO:0031347	regulation of defense response	biological_process	25.94349	27.18025	26.65584	26.73948	26.33927	26.90488	25.10485	27.17363	24.89794	26.39335	26.70357	27.74639	25.60121	25.87812	25.78099	27.50445	25.51594	27.38273	26.50579	27.21430	25.51266	28.20897	25.35373	26.20644	-1.236753	0.0003587	0.0016693
GO:0046083	adenine metabolic process	biological_process	23.33563	24.57224	24.05500	24.65831	24.39176	25.12596	22.65561	24.13968	22.78836	24.11648	23.92969	24.66279	23.21566	24.90980	21.67679	24.14292	22.41944	24.75954	23.61304	24.80872	22.48286	24.95073	23.22105	22.89591	-1.236619	0.0003493	0.0016398
GO:0016783	sulfurtransferase activity	molecular_function	24.37824	25.61432	23.58598	25.20558	25.18917	25.84369	24.17708	25.51545	24.07646	24.75044	24.63515	25.90590	24.39988	26.00148	23.84450	25.21686	24.55376	25.88925	24.35256	25.06111	24.60340	26.35295	24.06659	25.18026	-1.236079	0.0000051	0.0001299
GO:0040007	growth	biological_process	25.32359	26.55158	NA	NA	25.39983	25.62545	25.03395	25.61637	NA	NA	25.61460	26.18500	25.72829	27.44006	24.26167	26.78606	NA	NA	25.97157	27.17624	24.41941	25.82797	NA	NA	-1.227989	0.0091167	0.0224449
GO:0030388	fructose 1,6-bisphosphate metabolic process	biological_process	27.53147	28.75725	28.33940	27.82023	27.76395	28.53775	27.02146	28.95983	26.42962	28.44620	26.53710	27.78996	28.63352	29.44107	26.86390	29.55319	27.83259	28.83909	27.56425	28.77385	26.98603	28.66975	26.99173	28.42969	-1.225788	0.0001283	0.0008099
GO:0072655	establishment of protein localization to mitochondrion	biological_process	22.76584	23.98672	22.81924	24.36318	NA	NA	23.16079	NA	22.79078	23.28952	21.41116	NA	22.88863	NA	NA	NA	22.43283	24.62208	22.39417	23.19720	22.56509	23.32366	23.54256	24.38909	-1.220881	0.0028344	0.0085220
GO:0006168	adenine salvage	biological_process	23.32360	24.54440	24.02775	24.65831	24.39176	25.11989	22.65561	24.13968	22.78836	24.11648	23.88196	24.65823	23.21283	24.90090	21.64934	23.73134	22.41784	24.75489	23.60942	24.80259	22.48286	24.95073	23.22105	22.89591	-1.220802	0.0005129	0.0021647
GO:0006048	UDP-N-acetylglucosamine biosynthetic process	biological_process	22.11310	23.33383	22.84077	22.93604	22.65838	23.69206	21.56087	21.80282	21.29202	22.84206	22.46307	24.21909	21.73322	22.80190	21.16460	21.97438	21.88157	23.54559	22.61287	23.69300	20.94575	24.28958	22.56156	22.58026	-1.220734	0.0020263	0.0064039
GO:0016423	tRNA (guanine) methyltransferase activity	molecular_function	21.20116	22.42115	21.81605	22.25797	21.17531	22.17844	20.03665	22.41432	21.89175	21.69165	21.39272	22.87317	20.00297	22.25391	21.30743	23.49523	21.18725	22.29435	19.79402	21.32258	20.36418	22.68186	22.08454	21.94444	-1.219995	0.0003465	0.0016350
GO:0008998	ribonucleoside-triphosphate reductase activity	molecular_function	24.44108	25.66048	24.09690	25.53271	24.74938	25.96190	23.87759	25.82668	24.26795	25.07714	24.23000	25.13470	25.11572	26.39094	24.14052	25.41389	25.19008	25.83495	24.35941	25.66930	23.16738	25.92741	24.57759	24.73988	-1.219393	0.0000181	0.0002940
GO:0016226	iron-sulfur cluster assembly	biological_process	26.08204	27.30078	25.19557	26.78963	25.81331	27.46139	25.91372	27.04499	25.30029	27.40606	26.15509	27.28502	26.62884	27.85274	26.13932	26.97761	26.49376	27.25940	26.55406	27.07999	25.77150	27.56050	26.19381	27.28003	-1.218733	0.0000003	0.0000273
GO:0043096	purine nucleobase salvage	biological_process	23.32614	24.54464	24.02775	24.65831	24.39176	25.11989	22.65561	24.13968	22.78836	24.11648	23.88196	24.65823	23.21283	24.90090	21.64934	23.73134	22.46940	24.75716	23.60942	24.80259	22.48286	24.95073	23.22105	22.89591	-1.218497	0.0005144	0.0021677
GO:0004347	glucose-6-phosphate isomerase activity	molecular_function	26.03551	27.25027	26.55453	26.47211	26.90823	27.22284	25.07269	26.92892	25.26093	27.17174	25.22775	27.04895	26.01559	27.75187	25.58720	26.67691	26.14184	27.66624	26.54740	27.20771	25.68419	27.56471	26.12171	27.49165	-1.214760	0.0000106	0.0002035
GO:0003684	damaged DNA binding	molecular_function	23.82165	25.02870	24.34048	24.63980	24.74098	25.23132	23.97509	25.19841	22.68247	24.10783	23.44317	25.04813	24.38908	26.13145	22.09777	24.80507	23.29040	24.98878	23.96485	24.99362	23.46392	24.78363	23.79127	24.34463	-1.207052	0.0001990	0.0011039
GO:0006284	base-excision repair	biological_process	23.69114	24.89264	24.43324	25.07199	24.70299	25.27148	23.06208	25.16307	23.56610	24.11087	23.41918	24.77267	24.42094	25.47223	23.49129	24.66271	22.65289	25.04901	23.27719	24.98690	22.41597	24.41227	23.25558	24.18758	-1.201501	0.0000565	0.0005390
GO:0004534	5’-3’ exoribonuclease activity	molecular_function	24.35234	25.55134	25.00204	25.32040	25.06565	25.34311	22.88557	25.40211	23.44179	25.26632	24.80027	25.64863	24.98183	26.01411	23.41297	25.44587	23.60932	25.46275	24.96069	25.63148	23.58292	25.87052	23.94992	25.45783	-1.199003	0.0000280	0.0003938
GO:0044743	protein transmembrane import into intracellular organelle	biological_process	22.78908	23.98672	22.81924	24.36318	NA	NA	23.16079	NA	22.79078	23.28952	21.41116	NA	22.88863	NA	NA	NA	22.43283	24.62208	22.39417	23.19720	NA	23.32366	23.54256	24.38909	-1.197643	0.0052007	0.0141639
GO:0004075	biotin carboxylase activity	molecular_function	22.79220	23.98927	23.34311	23.09216	23.99934	24.09417	21.59450	23.61999	20.61572	23.45797	21.92145	24.09642	24.79589	24.97331	20.44429	23.73929	21.70593	23.13658	22.67579	24.34219	19.88825	24.60500	20.99847	23.39484	-1.197071	0.0013605	0.0046631
GO:0004462	lactoylglutathione lyase activity	molecular_function	23.85455	25.03680	24.35897	24.82091	23.68996	24.12687	23.75491	24.98633	23.65097	25.71328	24.72634	24.84350	23.57756	26.20070	22.32017	24.87445	23.41714	25.40800	24.66348	24.79909	23.13528	24.27599	23.51332	23.31152	-1.182249	0.0016844	0.0055492
GO:0008865	fructokinase activity	molecular_function	22.57857	23.75976	23.72096	22.82981	22.66392	24.10437	23.27181	23.96924	21.21408	23.37928	21.99357	22.80122	22.00263	24.83313	21.21047	23.90903	21.90371	24.09244	22.74201	23.64067	22.64298	23.13183	22.85287	23.29724	-1.181191	0.0005359	0.0022467
GO:0032264	IMP salvage	biological_process	23.38259	24.56189	24.84828	24.78151	23.77984	23.60470	22.56524	24.48943	22.94703	24.36712	22.63211	24.62767	23.62667	24.62971	22.44269	24.23383	23.20166	24.78619	22.73163	24.43214	22.95758	25.30365	23.45343	24.32745	-1.179304	0.0000345	0.0004186
GO:0044038	cell wall macromolecule biosynthetic process	biological_process	25.82588	27.00423	26.54885	27.06078	26.17657	26.91940	25.57150	27.26759	24.82353	26.49194	25.81540	27.58283	26.17701	27.24222	25.44437	26.60434	25.80385	27.01417	25.67239	26.43454	25.02669	27.21930	26.13873	26.75891	-1.178349	0.0000030	0.0000906
GO:0004151	dihydroorotase activity	molecular_function	22.94555	24.12238	23.75008	24.24016	22.68894	24.23517	22.90972	24.34774	21.03093	23.35888	23.31756	24.66128	22.69506	24.03577	23.08728	23.81186	22.12154	23.98618	22.58039	24.28369	21.24980	23.77561	24.13945	24.20643	-1.176833	0.0001776	0.0010221
GO:0001510	RNA methylation	biological_process	24.28396	25.46042	25.05989	24.65797	24.43457	25.44359	23.73038	25.09626	23.44699	24.91821	24.34099	25.98403	25.08469	26.33152	23.48264	25.08147	24.31456	25.54358	24.32209	25.19477	23.43517	26.11361	24.25025	24.38693	-1.176463	0.0001952	0.0010917
GO:0004073	aspartate-semialdehyde dehydrogenase activity	molecular_function	23.50783	24.66872	23.52961	23.18003	23.27873	24.97693	23.15539	24.40795	22.77624	24.49516	23.92187	24.45602	22.94334	25.12500	23.47389	24.59008	23.56197	24.24377	23.74576	24.18450	24.17327	25.66733	23.44474	24.73154	-1.160887	0.0000968	0.0006976
GO:0016703	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)	molecular_function	25.74757	26.90542	25.76466	26.15466	25.23792	26.49812	25.28694	26.88793	25.76060	26.53859	25.76715	27.40466	26.39799	27.14418	25.90950	26.55310	25.56518	26.79452	25.39941	26.91230	25.90260	27.80442	25.84195	26.42318	-1.157846	0.0000032	0.0000947
GO:0042742	defense response to bacterium	biological_process	24.37599	25.53118	23.31243	24.12861	26.68874	26.67778	21.19422	24.23103	21.98346	23.12512	22.84758	25.31947	25.48878	26.65346	21.20029	24.36125	21.76149	24.05542	25.57493	26.69586	20.62248	25.17690	21.04731	25.44887	-1.155183	0.0074336	0.0190070
GO:0005980	glycogen catabolic process	biological_process	23.64799	24.79758	23.50359	24.54371	23.50864	23.20080	23.38531	24.85340	23.45972	25.00334	23.26252	23.94116	23.91987	24.82791	23.72951	24.74503	23.48798	25.45336	23.65091	24.03390	23.60192	25.80262	24.30742	24.69097	-1.149594	0.0002834	0.0014284
GO:0016539	intein-mediated protein splicing	biological_process	22.51459	23.66038	22.04722	23.20418	22.59625	24.02997	22.82632	23.19847	22.27637	23.45800	21.88472	24.43649	22.33459	24.06599	21.65700	23.89501	23.67329	23.37947	22.03959	23.50046	22.93533	22.93351	22.11490	23.42225	-1.145790	0.0000270	0.0003880
GO:0098772	molecular function regulator	molecular_function	26.94386	28.08659	25.07996	26.67400	25.97086	28.68553	26.10896	27.32208	28.26185	27.36561	27.21299	26.36460	27.66852	28.60568	26.60291	29.09280	27.03419	28.20125	26.34465	27.10795	26.45641	29.05118	27.05076	27.41528	-1.142728	0.0106922	0.0256496
GO:0030163	protein catabolic process	biological_process	26.37626	27.51852	26.77457	27.93277	25.65320	NA	25.53063	27.82269	26.02785	26.58752	25.39884	27.42268	NA	NA	NA	NA	28.04789	27.76367	25.25411	27.17342	NA	NA	25.59347	NA	-1.142265	0.0061658	0.0163340
GO:0019730	antimicrobial humoral response	biological_process	24.30138	25.44120	23.00768	23.82889	26.68661	26.67182	20.83024	24.14213	21.46621	23.02197	22.13080	24.57513	25.46642	26.64883	20.22631	24.29813	20.49028	23.90621	25.57014	26.67865	19.94647	25.04901	20.72777	25.37780	-1.139821	0.0064350	0.0169072
GO:0019731	antibacterial humoral response	biological_process	24.30101	25.44039	23.00619	23.82406	26.68661	26.67182	20.83024	24.14213	21.46621	23.02197	22.13080	24.57513	25.46642	26.64883	20.19409	24.29444	20.46916	23.90117	25.57014	26.67865	19.94647	25.04386	20.72777	25.37780	-1.139374	0.0064496	0.0169209
GO:0004422	hypoxanthine phosphoribosyltransferase activity	molecular_function	23.42427	24.56180	24.84828	24.78151	23.77984	23.60470	22.56524	24.48943	22.94703	24.36712	23.20613	24.62850	23.62667	24.62971	22.44269	24.23147	23.20166	24.78619	22.73163	24.43214	23.01820	25.30365	23.45343	24.32745	-1.137534	0.0000417	0.0004667
GO:0052657	guanine phosphoribosyltransferase activity	molecular_function	23.42427	24.56180	24.84828	24.78151	23.77984	23.60470	22.56524	24.48943	22.94703	24.36712	23.20613	24.62850	23.62667	24.62971	22.44269	24.23147	23.20166	24.78619	22.73163	24.43214	23.01820	25.30365	23.45343	24.32745	-1.137534	0.0000417	0.0004667
GO:0009986	cell surface	cellular_component	30.15827	31.28697	30.70005	30.75382	31.11147	31.17068	29.64356	31.27722	29.33196	31.38042	29.74293	30.82446	30.70263	31.58777	29.79364	31.52364	29.81840	31.47796	30.38065	31.40082	29.11286	31.13671	30.03484	31.37868	-1.128697	0.0000069	0.0001541
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	molecular_function	25.79020	26.91837	25.91682	26.18557	25.23792	26.49961	25.31099	26.91619	25.89014	26.54037	25.77902	27.41106	26.45069	27.14476	25.91202	26.62796	25.56610	26.79809	25.39941	26.91672	25.91536	27.80721	25.88345	26.43848	-1.128166	0.0000048	0.0001252
GO:0004345	glucose-6-phosphate dehydrogenase activity	molecular_function	22.70189	23.82690	23.01382	24.33283	23.07399	23.64625	22.36365	23.51924	22.42070	23.02093	23.07275	24.72564	23.29580	24.21675	21.25768	22.24285	23.00059	23.68936	22.98105	23.96519	22.43778	24.21738	21.39537	22.79482	-1.125012	0.0018305	0.0058811
GO:0044273	sulfur compound catabolic process	biological_process	24.18524	25.30743	24.48238	25.02311	25.11787	24.34198	24.72513	25.94043	22.37007	25.41332	23.19124	24.54419	25.75993	25.81746	23.96945	24.98379	23.76311	25.33555	22.20489	24.45915	23.19106	26.07973	22.35330	25.22486	-1.122187	0.0017215	0.0056373
GO:0033567	DNA replication, Okazaki fragment processing	biological_process	20.31058	21.43198	19.82548	20.43854	19.69883	22.02672	19.81054	19.46763	19.48455	20.79072	20.77004	21.78352	21.05953	21.75560	20.01112	21.13118	19.78798	20.46876	18.96324	21.30107	20.51891	22.87578	21.47882	20.70542	-1.121392	0.0095008	0.0232014
GO:0042180	cellular ketone metabolic process	biological_process	26.41685	27.53673	24.93287	27.12231	28.11340	28.14260	25.14048	26.64804	25.64814	26.90156	25.99464	26.94082	24.67942	28.35922	24.68855	27.54141	26.91254	27.72284	27.34978	27.62062	26.39404	27.44391	26.00180	27.50050	-1.119879	0.0008891	0.0032699
GO:0004190	aspartic-type endopeptidase activity	molecular_function	25.05771	26.17739	25.95827	27.29358	22.66407	25.77832	23.22504	26.51115	24.36582	25.92962	22.91695	25.92731	22.08844	25.03056	24.99688	27.15733	27.66370	26.77293	22.08509	24.89969	23.26573	25.07550	22.91016	24.52086	-1.119683	0.0025665	0.0078469
GO:0015623	iron-chelate-transporting ATPase activity	molecular_function	22.91735	24.03353	23.24384	24.20369	23.81670	22.44216	21.05183	23.85654	21.12861	23.97576	22.01198	23.89090	23.06078	24.03032	21.76124	23.33461	24.30965	24.85214	23.01189	23.67729	22.44555	24.55872	22.62403	24.28934	-1.116189	0.0017331	0.0056568
GO:0004045	aminoacyl-tRNA hydrolase activity	molecular_function	20.11875	21.23332	20.53383	21.43528	18.85893	20.82378	19.06517	21.49331	19.48399	20.02736	19.66924	20.90888	20.45235	21.14895	19.89755	21.28384	21.08871	21.90694	20.24961	20.84173	19.26498	22.08372	20.85500	20.31218	-1.114568	0.0007153	0.0027382
GO:0008932	lytic endotransglycosylase activity	molecular_function	22.42124	23.53555	24.06689	23.94884	23.56976	23.26945	19.17056	23.16983	20.81187	22.16613	22.41672	24.55882	23.52451	23.26077	19.59111	21.28897	21.93011	23.69801	21.41878	23.06723	20.64629	24.40777	21.21279	23.43281	-1.114305	0.0090080	0.0222578
GO:0051304	chromosome separation	biological_process	19.65938	20.77206	19.24753	21.24301	20.88656	20.69806	18.61893	21.22972	17.31907	20.19389	21.73387	22.31600	19.74925	19.67584	17.52457	19.37648	17.29035	21.56459	19.77427	18.91555	13.82443	19.91815	18.42710	19.01364	-1.112681	0.0225109	0.0460381
GO:0019358	nicotinate nucleotide salvage	biological_process	23.85968	24.96937	24.24108	24.63390	24.86868	24.86896	23.65041	24.82278	23.16313	24.16974	24.00663	25.40480	24.14947	25.68268	23.35591	24.33245	23.25723	24.95515	23.00997	24.76394	23.10396	25.66559	24.30554	24.42174	-1.109692	0.0001192	0.0007735
GO:0035435	phosphate ion transmembrane transport	biological_process	20.99739	22.10517	21.25714	22.03379	21.52570	22.93305	19.84626	22.00226	18.68942	20.98627	19.32840	22.28810	20.39443	21.82143	19.58784	21.00976	23.40097	22.70827	19.46984	21.98856	19.43367	22.72488	19.61170	21.04355	-1.107782	0.0012031	0.0041763
GO:0004515	nicotinate-nucleotide adenylyltransferase activity	molecular_function	19.78287	20.88372	19.68533	19.28209	19.74243	20.58369	18.03773	20.44924	18.46009	20.32830	19.46581	21.93836	22.02032	22.10336	18.06373	20.47994	NA	20.05537	20.04854	20.72726	15.11761	21.61233	18.18919	18.22594	-1.100849	0.0203962	0.0428084
GO:0000155	phosphorelay sensor kinase activity	molecular_function	23.45075	24.54454	22.06907	23.86745	23.80093	23.47016	23.42333	23.81947	23.31369	23.78320	22.88474	26.22005	23.23978	25.41373	22.71061	24.46818	24.56942	24.59918	22.31675	23.56926	23.32428	24.18083	24.27420	23.26160	-1.093791	0.0123368	0.0285373
GO:0019365	pyridine nucleotide salvage	biological_process	23.87659	24.96978	24.24108	24.63390	24.86868	24.86896	23.65041	24.82278	23.16313	24.16974	24.00663	25.40480	24.14947	25.68268	23.35591	24.33245	23.51661	24.95973	23.00997	24.76394	23.10396	25.66559	24.30554	24.42174	-1.093190	0.0001267	0.0008045
GO:0009305	protein biotinylation	biological_process	19.46481	20.55766	17.07995	18.50963	NA	NA	18.21873	19.83137	18.64937	21.33458	20.85176	20.96020	19.11650	20.88518	18.50250	19.47728	20.14324	20.99663	19.22440	19.27739	20.27391	19.93886	18.96196	21.53738	-1.092846	0.0232621	0.0471487
GO:0008728	GTP diphosphokinase activity	molecular_function	21.73082	22.82241	22.28626	23.14815	21.61367	22.59590	20.91972	21.44535	21.05650	22.01029	22.61959	23.34084	21.91589	23.72431	20.58296	23.52324	20.71484	21.90710	21.35297	21.48701	21.60292	23.42041	22.57306	22.01379	-1.091582	0.0061731	0.0163373
GO:0030259	lipid glycosylation	biological_process	21.28610	22.37625	21.76810	20.44977	19.28512	21.34536	19.94521	21.68031	22.49954	21.93447	21.28050	22.58952	20.93561	22.82899	20.68838	21.77706	21.24182	21.51256	19.95725	21.28241	21.73224	23.83594	21.84029	23.33036	-1.090150	0.0226455	0.0462437
GO:0008853	exodeoxyribonuclease III activity	molecular_function	21.11041	22.19830	20.95581	23.53549	21.12051	22.66244	21.81468	21.45696	21.40793	21.72512	20.15266	21.90703	20.74269	22.46119	20.40198	20.94122	21.26950	22.57603	19.79910	21.27473	21.72805	22.23662	21.46707	21.15867	-1.087889	0.0037645	0.0108388
GO:0031072	heat shock protein binding	molecular_function	24.42742	25.51028	25.23192	25.07699	22.19629	24.96366	23.30629	25.86825	25.68328	25.39836	23.79574	25.37779	25.39167	25.73143	23.82341	24.96490	24.80944	26.02084	23.91162	25.28534	22.63829	26.03660	23.79779	25.33279	-1.082863	0.0008604	0.0031992
GO:0003952	NAD+ synthase (glutamine-hydrolyzing) activity	molecular_function	22.76370	23.84382	21.74648	22.77041	23.17451	23.97940	23.23417	24.57453	22.37792	23.37414	23.86557	23.83723	22.78444	24.88600	21.15798	23.34066	22.44793	22.88893	21.46996	23.29142	20.24313	24.68458	23.86845	22.08552	-1.080121	0.0115176	0.0270934
GO:0008763	UDP-N-acetylmuramate-L-alanine ligase activity	molecular_function	23.63528	24.71419	23.37207	23.53326	24.02009	24.68207	23.20102	24.39226	23.78598	24.11268	23.56354	24.31604	24.01418	25.41027	23.68746	24.92178	23.28381	24.52751	23.38640	24.66742	23.70210	25.36000	23.70495	24.94910	-1.078906	0.0000220	0.0003358
GO:0044036	cell wall macromolecule metabolic process	biological_process	26.12420	27.19866	26.80031	27.19757	26.49571	27.22307	25.73895	27.54840	25.12546	26.80597	26.15055	27.71324	26.56127	27.37007	25.77731	26.72568	26.07960	27.27700	25.92654	26.70382	25.43338	27.26197	26.41439	26.98468	-1.074463	0.0000055	0.0001350
GO:0008239	dipeptidyl-peptidase activity	molecular_function	22.03308	23.10682	23.13753	23.06002	23.76787	23.06155	19.70821	22.48595	17.91386	20.93853	23.14861	24.40734	20.64103	23.65906	18.12751	20.99148	21.48880	22.92098	22.28901	22.96196	16.68149	22.70148	21.60942	23.68314	-1.073741	0.0176138	0.0379353
GO:0019877	diaminopimelate biosynthetic process	biological_process	25.06164	26.13341	24.77617	24.70195	24.49815	25.28566	24.85184	25.98866	24.12214	26.35206	25.69366	26.24109	24.77588	26.68741	25.16235	26.79452	25.24123	25.92644	25.57297	25.44694	25.33577	26.33965	24.92128	26.44037	-1.071770	0.0003571	0.0016650
GO:0009088	threonine biosynthetic process	biological_process	24.99988	26.07145	25.12420	25.28032	25.12035	25.70508	24.27890	25.50047	23.58350	25.51488	24.94642	26.37350	26.14564	26.76108	24.07204	26.09630	25.25620	25.65351	25.30656	25.76640	25.05880	27.19018	24.41497	25.55839	-1.071578	0.0008032	0.0030153
GO:0043532	angiostatin binding	molecular_function	24.22639	25.29123	24.53209	23.70131	26.35806	26.50506	20.91944	24.92864	22.84123	25.19999	22.39535	23.52655	24.52113	26.10603	NA	24.97265	21.01407	24.56300	25.09952	26.28632	21.87057	24.08939	22.25616	24.86655	-1.064839	0.0111179	0.0264111
GO:0035821	modification of morphology or physiology of other organism	biological_process	28.08288	29.14630	28.68164	28.82582	27.72732	28.41141	28.13175	29.19722	27.80272	28.95034	28.36325	29.47697	26.97498	27.77953	28.25172	29.58374	28.47726	29.63749	27.99631	28.83064	27.05594	29.90783	28.45759	28.79796	-1.063416	0.0004871	0.0021022
GO:0004516	nicotinate phosphoribosyltransferase activity	molecular_function	23.91058	24.96976	24.56551	24.63534	24.86868	24.86896	23.65041	24.82278	23.19985	24.17112	24.00663	25.40480	24.20800	25.68309	23.35591	24.33508	23.25723	24.95515	23.00997	24.76394	23.10396	25.66559	24.30554	24.42174	-1.059184	0.0002403	0.0012582
GO:0016758	transferase activity, transferring hexosyl groups	molecular_function	27.55370	28.60866	28.04766	28.34079	28.21349	27.60093	26.58569	27.98863	26.59586	28.43922	27.31568	27.77112	28.31131	29.61359	26.79814	29.25534	27.14374	28.37841	27.70183	28.28457	27.44326	29.22459	27.64840	28.31608	-1.054957	0.0009261	0.0034016
GO:0019674	NAD metabolic process	biological_process	26.77815	27.83288	27.15239	27.26398	27.34201	27.96614	26.01657	27.49609	25.90978	27.59648	26.29973	27.43204	27.38546	28.61006	26.71348	27.44872	27.48133	27.77772	26.65315	27.91892	25.73323	28.23538	26.56211	27.84045	-1.054726	0.0000630	0.0005691
GO:0043115	precorrin-2 dehydrogenase activity	molecular_function	18.86040	19.91460	NA	NA	NA	NA	17.30860	19.51831	15.97341	20.11480	18.61021	NA	17.98226	20.64957	NA	19.04717	20.27284	18.37844	17.05183	19.64429	16.51328	19.33287	20.44296	20.94085	-1.054192	0.0225032	0.0460381
GO:0004396	hexokinase activity	molecular_function	24.76313	25.81488	25.82495	25.18876	26.21320	26.30352	24.05458	25.32473	23.33056	25.31964	24.07150	25.59342	25.14315	26.66842	23.42659	26.07761	24.21313	25.68803	24.92538	26.00987	23.71161	25.76263	24.01850	25.16706	-1.051756	0.0007199	0.0027519
GO:0001522	pseudouridine synthesis	biological_process	23.56670	24.61630	24.20748	24.63291	22.73340	24.10245	23.45985	24.48329	22.76727	24.01588	24.07372	24.70948	24.10833	24.93120	22.17840	24.20655	24.13431	24.89038	23.07870	24.55345	23.12967	25.50223	23.81026	23.96932	-1.049598	0.0002471	0.0012794
GO:0046417	chorismate metabolic process	biological_process	24.31137	25.36074	24.42019	25.01028	24.04475	24.48003	23.46517	25.25686	22.65637	24.95202	24.74760	25.76911	24.30390	25.94261	24.15237	25.69902	24.78246	25.37876	24.30134	24.46203	24.05420	25.88695	25.12456	25.22694	-1.049368	0.0003907	0.0017759
GO:0009143	nucleoside triphosphate catabolic process	biological_process	23.06459	24.10994	23.04473	23.98857	23.72171	24.42238	23.28050	24.30906	23.62852	23.52840	23.22829	24.49447	23.51934	24.16228	22.74058	23.59849	22.47893	24.25501	22.06082	23.84920	22.21038	24.71966	22.72313	23.14504	-1.045351	0.0001031	0.0007242
GO:0033643	host cell part	cellular_component	24.12666	25.17062	22.60938	24.64821	22.09632	23.74103	NA	25.54280	23.79218	25.66771	24.29433	25.37671	21.89380	25.11349	24.71846	24.43467	25.66045	26.21869	NA	24.61173	24.76935	25.65938	22.45079	23.70433	-1.043964	0.0112776	0.0266313
GO:0008171	O-methyltransferase activity	molecular_function	21.63187	22.67470	21.70513	21.89674	22.81156	22.40438	20.38333	22.56089	21.64702	22.01098	22.40175	23.11895	20.77516	22.62171	21.01790	21.49386	21.09141	22.29397	20.66910	21.64423	21.45132	24.47238	21.96240	21.76540	-1.042830	0.0118312	0.0276979
GO:1902012	poly(ribitol phosphate) teichoic acid biosynthetic process	biological_process	21.50824	22.55036	23.09216	22.99114	22.18726	21.41874	19.90296	22.78465	17.54106	21.96316	20.07897	22.95283	21.98961	22.03727	18.51284	21.37605	22.24817	23.12799	20.56503	21.46005	21.67135	23.28597	21.19685	22.87412	-1.042119	0.0108090	0.0258845
GO:0006465	signal peptide processing	biological_process	23.19937	24.23828	23.26751	23.96931	23.97320	24.26723	22.36380	23.86461	23.04240	23.72783	24.16883	24.95709	22.11124	23.05406	22.55498	22.76619	23.19747	24.22574	23.09985	24.74110	22.13101	23.95894	23.58608	25.23636	-1.038911	0.0034155	0.0100251
GO:0004040	amidase activity	molecular_function	24.58209	25.60981	25.54571	25.23296	25.51061	25.50312	23.83158	26.01815	24.38061	25.20147	24.36937	25.87036	24.67661	25.58781	24.14173	25.62931	24.13322	25.53628	24.06160	25.73209	23.93972	25.76820	24.49958	25.40773	-1.027722	0.0000091	0.0001836
GO:0098661	inorganic anion transmembrane transport	biological_process	21.08172	22.10813	21.25714	22.03379	21.52570	22.93305	19.84626	22.00226	18.68942	20.98627	19.32840	22.28810	20.39443	21.82143	19.58784	21.00976	23.57107	22.72952	19.46984	21.98856	19.43367	22.72488	19.61170	21.04355	-1.026409	0.0015853	0.0053195
GO:0050580	2,5-didehydrogluconate reductase activity	molecular_function	21.47463	22.49806	22.64844	22.54676	22.20309	20.49921	20.32726	22.68743	19.15640	22.45026	19.09249	22.51259	21.63384	22.19443	20.61727	22.48523	21.56641	22.73836	20.24023	20.54483	22.87549	23.60439	20.30112	22.76573	-1.023431	0.0139480	0.0314090
GO:0004152	dihydroorotate dehydrogenase activity	molecular_function	22.52285	23.54066	22.34800	23.15544	20.32471	22.35735	22.52827	24.00842	21.83213	23.48552	22.21921	24.25379	23.52796	24.55555	22.18715	23.08095	23.28495	23.29641	21.36543	22.45109	22.62824	23.71473	23.05208	22.84850	-1.017811	0.0053575	0.0145279
GO:0004385	guanylate kinase activity	molecular_function	21.76630	22.77977	21.76165	22.54154	22.48027	22.85410	20.44721	22.67673	21.75519	22.74630	22.62907	23.52513	21.94608	23.89820	20.31194	21.82072	21.41637	22.62463	21.46784	22.54041	21.52719	21.68216	22.03969	22.08284	-1.013470	0.0025148	0.0077323
GO:0098542	defense response to other organism	biological_process	24.54683	25.56003	23.33691	24.15471	26.79939	26.69592	21.78605	24.23489	21.98346	23.12512	23.62083	25.40323	25.60324	26.69976	21.22247	24.38314	23.19081	24.10368	25.58820	26.70004	21.10532	25.20267	22.48143	25.48508	-1.013202	0.0177937	0.0382621
GO:0003883	CTP synthase activity	molecular_function	23.73342	24.74518	22.38397	24.60701	20.84653	24.82153	23.31012	24.54535	22.69177	24.59416	24.55515	24.33756	24.12838	25.41072	22.89449	24.24012	24.83759	24.37743	24.00513	24.64777	24.22074	25.59447	23.48287	24.25056	-1.011760	0.0026564	0.0080944
GO:0004340	glucokinase activity	molecular_function	24.40471	25.41546	25.44298	24.87594	26.08438	25.94920	22.79874	24.59103	22.95235	24.88416	23.68154	25.35317	24.96950	26.19402	23.07695	25.71465	23.88805	25.10835	24.56663	25.69952	22.77713	25.50859	23.16705	24.70589	-1.010746	0.0018002	0.0058075
GO:0030488	tRNA methylation	biological_process	22.90375	23.91306	23.65249	23.07666	22.91487	24.07988	22.76329	23.51045	22.12374	22.82406	23.05817	25.03983	23.60575	24.75500	21.04300	23.19834	23.11178	23.30734	22.80404	23.87563	22.47006	24.55922	22.87257	22.21782	-1.009306	0.0146951	0.0326051
GO:0004813	alanine-tRNA ligase activity	molecular_function	25.83203	26.83644	25.92845	26.25022	25.91075	27.23634	25.56108	26.10094	25.61153	25.92795	26.02526	26.81984	25.85565	27.33845	25.41847	26.44468	25.61980	26.89940	25.84876	26.98871	26.08976	27.19522	26.10307	27.18803	-1.004417	0.0000137	0.0002435
GO:0033293	monocarboxylic acid binding	molecular_function	24.66248	25.66571	24.70978	25.17968	24.46683	25.38956	24.13425	25.48904	24.43483	26.17767	25.41115	26.13672	24.45320	25.70347	24.15374	25.83108	25.35976	25.46994	24.25083	24.90120	24.21043	24.69796	24.91801	26.38147	-1.003229	0.0001532	0.0009212
GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	molecular_function	26.31210	27.31472	26.49270	26.46334	26.73059	27.16103	25.45730	26.99335	25.50838	26.56377	26.07387	27.86020	27.24514	27.93888	25.27239	27.31969	26.62501	27.17549	26.70108	27.33879	25.87268	27.82253	26.11396	26.99507	-1.002620	0.0002945	0.0014770
GO:0016743	carboxyl- or carbamoyltransferase activity	molecular_function	29.45183	28.43873	29.61372	27.11805	29.88880	28.42287	28.37712	28.50825	28.97036	28.89083	30.03587	28.33234	29.40854	28.63899	28.92391	28.15145	29.33026	28.38689	30.36917	29.52119	28.79659	26.76355	28.99906	28.28750	1.013095	0.0016216	0.0053883
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	molecular_function	31.30552	30.28991	30.84746	29.02619	30.90158	30.37365	31.16648	30.16074	31.45891	30.54115	31.41758	29.71322	31.98660	30.60282	30.86918	30.10767	31.56569	30.68709	31.05226	30.37959	31.07504	30.42680	31.54902	30.48468	1.015609	0.0000142	0.0002487
GO:0044255	cellular lipid metabolic process	biological_process	31.42428	30.39415	30.18307	29.24788	28.88636	28.89403	31.44801	30.85937	31.92953	31.22841	31.73072	29.80470	31.98543	30.16803	31.54805	30.54349	31.76561	30.97370	30.55931	29.90110	31.52846	30.25120	31.77627	30.76383	1.030131	0.0144957	0.0322438
GO:0008169	C-methyltransferase activity	molecular_function	24.36112	23.32838	23.60551	20.91466	24.80966	22.61111	24.27177	23.08273	22.73331	23.56052	25.06321	22.20106	23.43295	24.24492	23.65592	24.05200	23.76168	22.78304	25.30375	23.12727	24.48266	23.21600	24.78752	24.10176	1.032740	0.0090499	0.0223208
GO:0019627	urea metabolic process	biological_process	26.67366	25.63639	27.48780	24.60411	27.84293	26.06522	25.68776	24.93351	26.34275	25.72074	26.29780	23.79358	26.71152	25.98314	26.63838	26.27441	25.57128	25.48800	26.97686	26.27792	25.57045	25.95383	26.26751	25.07008	1.037269	0.0054260	0.0146744
GO:0019262	N-acetylneuraminate catabolic process	biological_process	23.34272	22.30151	23.50050	20.91810	23.79855	22.42115	22.84943	24.22919	22.17629	20.10148	23.17289	21.65930	23.61226	22.56193	23.07686	22.25124	23.73866	21.47011	23.66175	22.55682	22.64685	20.82214	23.66495	21.53940	1.041210	0.0012359	0.0042791
GO:0042402	cellular biogenic amine catabolic process	biological_process	25.76947	24.72601	21.29272	19.25776	NA	19.54966	26.09617	20.54477	25.30067	24.61810	25.55668	21.00407	22.19140	17.73135	24.82251	17.22057	27.74384	27.99748	25.29798	20.86007	24.59565	21.58220	26.27439	20.06660	1.043458	0.0022640	0.0070650
GO:0004585	ornithine carbamoyltransferase activity	molecular_function	28.66121	27.61166	29.10296	26.59097	29.39999	27.95563	27.47311	27.77618	27.93343	27.82013	29.17527	27.33029	28.67208	27.89481	28.01159	27.22073	28.09496	27.39394	29.71335	28.77005	27.22273	25.68489	28.22536	27.29744	1.049552	0.0072688	0.0186560
GO:0008374	O-acyltransferase activity	molecular_function	23.75906	22.67786	21.43665	21.55176	23.48095	23.32102	23.25699	22.40212	23.16555	22.59499	24.91947	23.14335	22.87358	22.43811	23.10108	22.08242	23.09755	22.24851	24.24715	22.97147	24.23407	22.53823	24.58406	23.20824	1.081198	0.0140977	0.0315911
GO:0006767	water-soluble vitamin metabolic process	biological_process	29.22423	28.14163	26.94067	26.50404	27.13225	27.18582	29.87656	28.11434	29.56658	28.66292	29.45745	27.89311	29.32197	28.66420	29.01074	27.84274	30.25449	28.87244	28.24093	27.62132	29.33825	27.89297	29.19818	28.68456	1.082605	0.0244866	0.0492267
GO:0006766	vitamin metabolic process	biological_process	29.75112	28.66846	27.49886	26.98819	27.63066	27.65141	30.42623	28.66242	30.08482	29.21865	29.95013	28.40298	29.82964	29.16997	29.54129	28.37511	30.78769	29.40897	28.77450	28.14286	29.87117	28.37626	29.73429	29.24189	1.082658	0.0245404	0.0492834
GO:0042364	water-soluble vitamin biosynthetic process	biological_process	28.03080	26.94290	25.85845	25.17395	25.84892	25.75944	28.76767	26.99001	28.29194	27.56868	28.15387	26.57890	28.07220	27.39765	27.83858	26.67188	29.09159	27.71987	27.07430	26.41725	28.15688	26.49884	28.04043	27.59415	1.087904	0.0237249	0.0479438
GO:0043190	ATP-binding cassette (ABC) transporter complex	cellular_component	29.40935	28.31922	28.47007	28.09480	29.07682	28.64654	29.80670	28.44715	29.46436	27.90724	29.87286	28.37653	29.68709	28.80181	29.47469	27.50617	28.27080	28.77406	28.34182	28.17287	29.22242	28.08380	30.32093	28.19022	1.090139	0.0003821	0.0017537
GO:1902495	transmembrane transporter complex	cellular_component	29.41096	28.32063	28.47007	28.09480	29.07725	28.65508	29.80670	28.44715	29.46557	27.90724	29.87403	28.37726	29.68756	28.80219	29.47469	27.50617	28.29248	28.77568	28.34182	28.17287	29.22242	28.08425	30.32306	28.19121	1.090336	0.0003684	0.0017031
GO:0006304	DNA modification	biological_process	26.05878	24.96631	25.21181	25.41485	24.42478	25.39776	26.86361	24.98016	25.17962	24.65744	26.41402	25.54465	25.51042	24.39797	26.19566	24.28028	24.97050	25.74544	25.41074	24.21730	26.35240	24.48483	27.34241	24.35238	1.092464	0.0075854	0.0193406
GO:1904949	ATPase complex	cellular_component	29.43237	28.33635	28.48082	28.09621	29.09003	28.65878	29.81673	28.45066	29.46738	27.91820	29.89905	28.37878	29.69315	28.80831	29.49367	27.58027	28.42605	28.82187	28.42295	28.17690	29.25204	28.09797	30.33064	28.21593	1.096028	0.0002217	0.0011837
GO:1901661	quinone metabolic process	biological_process	24.19400	23.09791	21.50039	19.30683	22.98657	21.80351	23.88604	23.04223	24.22863	22.79932	24.32593	22.47862	22.96458	24.93375	23.83519	23.17091	24.96169	22.77461	24.71993	22.23476	25.32506	22.11951	24.11340	23.79003	1.096091	0.0227848	0.0463888
GO:0006207	‘de novo’ pyrimidine nucleobase biosynthetic process	biological_process	26.93960	25.84154	26.67107	24.32794	24.68483	25.54353	26.63954	25.82879	26.55428	26.42069	27.40744	25.88182	27.29745	26.03134	26.56312	25.32968	27.21685	26.16113	27.28521	26.15137	27.50982	25.49625	26.91084	26.11213	1.098057	0.0020322	0.0064109
GO:1901663	quinone biosynthetic process	biological_process	23.19677	22.09828	20.50039	18.30683	21.98657	20.80351	22.88604	22.04223	23.22863	21.79932	23.32593	21.47862	21.96458	23.93375	22.83519	22.17091	23.97948	21.77965	23.71993	21.23476	24.32506	21.11951	23.11340	22.79003	1.098494	0.0227564	0.0463657
GO:0006084	acetyl-CoA metabolic process	biological_process	28.78418	27.66671	27.49563	25.24523	27.71039	26.90922	28.84836	27.48907	29.15607	28.53726	28.98668	26.83021	29.03376	27.44076	28.76489	27.47423	28.88110	27.88642	28.54315	27.31729	29.16444	27.20265	29.08580	29.01427	1.117467	0.0010354	0.0036971
GO:0006575	cellular modified amino acid metabolic process	biological_process	29.03679	27.91745	27.48615	27.62637	28.51974	27.96356	28.40816	27.83718	29.08007	27.56585	28.45285	27.85132	29.74019	28.03693	28.44862	27.55369	30.50368	28.76375	27.84320	27.64073	29.15573	27.59384	29.08572	28.15566	1.119340	0.0034424	0.0100931
GO:0006004	fucose metabolic process	biological_process	25.59407	24.46807	25.42034	22.15874	26.35927	22.45457	25.62904	23.87800	24.06890	23.24385	24.65945	21.41853	26.27925	25.68305	25.70361	21.32038	26.92275	25.54256	24.31741	24.45730	24.20189	25.71166	24.66842	24.99099	1.125997	0.0143383	0.0319701
GO:0015074	DNA integration	biological_process	27.31969	26.18881	26.60221	25.66339	25.74245	25.86047	26.88641	26.00273	27.03396	25.60527	27.61806	26.62650	27.95722	26.74194	26.90761	25.96000	27.89003	26.65046	27.76883	25.91206	27.25352	26.33857	27.52578	26.15302	1.130875	0.0001882	0.0010678
GO:0016417	S-acyltransferase activity	molecular_function	27.01680	25.87931	25.09691	24.33562	26.32899	26.24014	26.75590	25.89994	26.39715	25.97716	27.54362	25.52933	27.48570	25.69401	26.02558	25.32985	27.21096	25.59042	27.35000	25.12004	27.29447	26.76146	27.77002	26.63503	1.137486	0.0025757	0.0078659
GO:1990204	oxidoreductase complex	cellular_component	27.03917	25.90152	25.60441	25.15208	26.21106	26.85490	26.50091	25.68702	25.48832	25.27038	27.23236	25.23727	27.56162	25.83818	26.02352	25.62130	28.19354	26.04135	27.45238	25.56478	27.48214	26.57700	27.10362	25.98423	1.137646	0.0045209	0.0126028
GO:0046854	phosphatidylinositol phosphorylation	biological_process	22.16076	21.02038	22.33957	19.42143	21.58337	17.73713	21.66991	17.17349	20.80232	18.49469	22.71657	20.18776	20.61054	23.33587	20.45283	19.05494	22.66664	20.97809	23.36638	18.54516	22.40186	21.25682	22.25898	22.15768	1.140377	0.0048203	0.0132910
GO:0015408	ferric-transporting ATPase activity	molecular_function	24.05499	22.91064	22.77349	22.22491	22.02799	22.08796	23.99135	22.57116	23.72130	22.88995	24.50505	23.13425	23.35220	23.58142	24.15721	22.22955	21.93956	22.41411	24.50430	22.69608	25.26536	23.51989	24.75889	23.54981	1.144357	0.0227099	0.0463405
GO:0055114	oxidation-reduction process	biological_process	31.20342	30.05048	29.69937	28.90328	30.17245	29.63890	31.15665	29.97392	31.76688	30.42869	31.50741	29.43450	31.82406	30.30845	31.30060	29.83758	30.84754	30.54228	30.92768	30.14388	31.30555	29.68392	31.45386	30.71847	1.152939	0.0002715	0.0013898
GO:0033875	ribonucleoside bisphosphate metabolic process	biological_process	29.99591	28.81495	28.91019	27.37542	29.18313	28.73369	29.90909	28.62011	30.43978	29.22025	30.20191	28.36339	30.29885	28.92520	29.71759	28.66001	29.99438	29.00603	29.92547	28.64660	30.36802	28.80941	30.25949	29.62361	1.180954	0.0000314	0.0004042
GO:0034032	purine nucleoside bisphosphate metabolic process	biological_process	29.99591	28.81495	28.91019	27.37542	29.18313	28.73369	29.90909	28.62011	30.43978	29.22025	30.20191	28.36339	30.29885	28.92520	29.71759	28.66001	29.99438	29.00603	29.92547	28.64660	30.36802	28.80941	30.25949	29.62361	1.180954	0.0000314	0.0004042
GO:0042558	pteridine-containing compound metabolic process	biological_process	29.36448	28.18012	27.75983	27.80365	28.83008	28.43052	28.60277	28.10465	29.33886	27.81098	28.81823	28.05312	30.15480	28.42654	28.67970	28.05883	30.99465	28.95604	28.05629	27.96336	29.36615	27.81873	29.16638	28.09750	1.184358	0.0048114	0.0132899
GO:0033748	hydrogenase (acceptor) activity	molecular_function	24.99055	23.80591	22.24330	NA	NA	NA	24.52008	23.59063	24.15813	24.64032	25.30967	23.17052	24.03012	22.91811	24.85426	22.99693	25.78683	23.56346	25.62727	22.39059	25.50319	22.28098	25.22729	25.40654	1.184638	0.0156944	0.0343734
GO:0008736	L-fucose isomerase activity	molecular_function	23.78299	22.59792	23.45499	19.84706	24.48490	20.37684	23.86870	21.18720	22.28374	21.04070	22.93844	19.13021	24.41734	23.80931	23.80948	17.93044	25.21293	23.76007	22.50962	22.75874	22.37243	23.96739	22.92010	23.21717	1.185069	0.0115232	0.0270934
GO:0042355	L-fucose catabolic process	biological_process	23.78975	22.59792	23.50668	19.84706	24.48490	20.37684	23.86870	21.18720	22.28374	21.04070	22.99596	19.13021	24.41734	23.80931	23.80948	17.93044	25.21293	23.76007	22.50962	22.75874	22.37243	23.96739	22.92010	23.21717	1.191835	0.0111261	0.0264111
GO:0006637	acyl-CoA metabolic process	biological_process	29.53906	28.34279	28.36714	26.58372	28.63899	28.10441	29.51366	28.16516	29.94169	28.91593	29.74409	27.69137	29.80994	28.37182	29.35510	28.15673	29.57673	28.56194	29.44820	28.15427	29.90751	28.18471	29.82585	29.35084	1.196271	0.0001041	0.0007288
GO:2001295	malonyl-CoA biosynthetic process	biological_process	25.45896	24.26167	23.69585	23.51711	24.22835	24.28544	25.66880	23.91953	25.51427	23.27154	25.94976	24.01451	25.12525	25.10296	25.44310	24.08833	25.34197	24.50907	25.97011	24.20231	25.42055	24.90191	26.11414	24.05726	1.197292	0.0004938	0.0021203
GO:0033865	nucleoside bisphosphate metabolic process	biological_process	31.32631	30.12789	30.27741	28.77195	30.55990	30.14060	31.20627	29.93782	31.79230	30.45524	31.52122	29.71484	31.64823	30.27358	30.99616	29.97972	31.31032	30.31588	31.27230	29.99426	31.70307	30.16645	31.57314	30.83426	1.198423	0.0000157	0.0002660
GO:0098797	plasma membrane protein complex	cellular_component	29.54270	28.33858	28.51748	28.09508	29.07806	28.65404	29.86821	28.44813	29.51955	27.93901	30.04318	28.38035	29.73268	28.80464	29.56235	27.51688	28.65720	28.81045	29.04495	28.18301	29.40266	28.08676	30.40720	28.29899	1.204122	0.0000241	0.0003585
GO:0051536	iron-sulfur cluster binding	molecular_function	29.36904	28.15994	28.05804	24.94594	26.88012	26.26243	29.37784	28.56589	29.74049	28.74499	29.63657	27.41768	30.13445	28.28202	29.33155	28.53513	29.08448	28.41104	29.16029	27.77108	29.73095	27.53604	29.71351	29.30590	1.209095	0.0085189	0.0212424
GO:0035383	thioester metabolic process	biological_process	29.96717	28.73709	28.86671	27.15438	29.14989	28.67719	29.88965	28.56710	30.39851	29.19181	30.15970	28.14668	30.27086	28.82786	29.69794	28.55379	29.98035	28.95533	29.90562	28.61409	30.34171	28.66024	30.22932	29.59144	1.230080	0.0000329	0.0004116
GO:0006099	tricarboxylic acid cycle	biological_process	28.64178	27.40835	26.98105	24.80592	26.93039	26.77090	28.28107	27.21620	27.82496	27.77972	28.97039	26.75615	27.97440	27.57701	27.80693	27.63409	29.77066	27.12131	29.66708	27.00167	29.08427	26.93643	28.64839	28.89323	1.233436	0.0081941	0.0205646
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	molecular_function	30.07191	28.83820	28.79137	26.56950	27.51689	27.19381	29.95296	29.06655	30.46741	29.47323	30.56604	28.34817	30.93112	29.11402	29.99261	29.22960	29.80403	29.01397	30.18557	28.70107	30.05061	28.26074	30.22900	29.69000	1.233707	0.0058195	0.0155990
GO:0042578	phosphoric ester hydrolase activity	molecular_function	28.23133	26.99540	26.58455	26.67821	26.46172	26.78785	28.67131	26.85773	27.23893	26.42511	28.63459	27.15077	28.34313	27.36919	27.51704	25.93139	27.85220	27.12881	29.17204	27.11647	29.08561	26.79788	28.25891	27.84714	1.235923	0.0033679	0.0099177
GO:0072350	tricarboxylic acid metabolic process	biological_process	28.65483	27.41134	26.98259	24.80592	26.93039	26.77090	28.30419	27.22327	27.83376	27.78057	28.97799	26.75631	27.97818	27.57763	27.84013	27.63435	29.77684	27.13386	29.67499	27.00345	29.09915	26.93661	28.68743	28.89780	1.243490	0.0078086	0.0198168
GO:0052547	regulation of peptidase activity	biological_process	20.32733	19.07691	NA	NA	NA	16.05976	20.27155	17.34016	19.73841	18.65508	19.47110	NA	NA	NA	19.54242	17.63970	21.11830	21.23676	20.39448	15.34216	20.75408	19.44462	20.48850	18.40253	1.250412	0.0066936	0.0174432
GO:0009790	embryo development	biological_process	22.09350	20.83641	20.17445	NA	NA	NA	21.34117	21.80694	21.14453	17.99335	21.94361	22.29146	21.79001	18.30092	22.47524	NA	23.51290	20.03634	22.37277	14.30129	21.76293	21.86135	21.98235	19.38999	1.257093	0.0180839	0.0387635
GO:0015930	glutamate synthase activity	molecular_function	24.30084	23.04196	23.99506	19.87308	NA	NA	22.97892	22.91014	24.21158	24.50684	24.27364	22.45066	24.47954	22.15859	23.01301	21.67410	24.41789	23.21536	25.02738	23.01055	25.28681	21.31146	23.58402	24.18921	1.258881	0.0047942	0.0132695
GO:0070006	metalloaminopeptidase activity	molecular_function	24.46864	23.20570	23.90572	22.01453	22.51644	23.49740	24.17520	22.93512	25.47452	22.54634	25.07681	22.23947	23.99773	24.15309	24.13163	23.62127	25.21619	23.49735	22.89888	23.12215	24.01421	23.45127	25.01202	22.78762	1.262939	0.0033590	0.0099108
GO:0046653	tetrahydrofolate metabolic process	biological_process	28.23377	26.96576	26.99005	26.62200	28.07622	27.14956	27.84955	26.69471	28.61690	26.61398	27.88898	26.82242	28.71095	27.02187	27.91513	26.27212	28.97986	28.09894	27.32696	27.01373	28.67448	26.41897	28.32007	26.94937	1.268005	0.0000370	0.0004415
GO:0033866	nucleoside bisphosphate biosynthetic process	biological_process	29.03780	27.76942	28.12365	26.71498	28.43861	28.11594	28.78086	27.59889	29.58663	27.72122	29.18881	27.50531	29.43117	28.05289	28.48650	27.64890	28.96415	27.94460	29.04589	27.77091	29.43249	27.97701	29.21765	27.95441	1.268381	0.0000014	0.0000586
GO:0034030	ribonucleoside bisphosphate biosynthetic process	biological_process	28.03780	26.76942	27.12365	25.71498	27.43861	27.11594	27.78086	26.59889	28.58663	26.72122	28.18881	26.50531	28.43117	27.05289	27.48650	26.64890	27.96415	26.94460	28.04589	26.77091	28.43249	26.97701	28.21765	26.95441	1.268381	0.0000014	0.0000586
GO:0034033	purine nucleoside bisphosphate biosynthetic process	biological_process	28.03780	26.76942	27.12365	25.71498	27.43861	27.11594	27.78086	26.59889	28.58663	26.72122	28.18881	26.50531	28.43117	27.05289	27.48650	26.64890	27.96415	26.94460	28.04589	26.77091	28.43249	26.97701	28.21765	26.95441	1.268381	0.0000014	0.0000586
GO:0006760	folic acid-containing compound metabolic process	biological_process	28.93622	27.66648	27.41574	27.30204	28.48942	27.90286	28.26978	27.54389	29.02027	27.32073	28.36029	27.47889	29.65047	27.81684	28.34767	27.39450	30.44130	28.59724	27.74108	27.53184	29.06105	27.21301	28.76108	27.63176	1.269738	0.0010776	0.0038137
GO:0072341	modified amino acid binding	molecular_function	27.42397	26.13811	27.53424	26.20412	26.60827	25.15831	27.16986	27.16442	27.59470	26.86156	26.83273	24.56421	27.37040	23.80059	27.69306	25.87447	28.27245	27.47555	26.01203	25.54126	27.70830	24.76844	27.64017	25.84517	1.285863	0.0007317	0.0027932
GO:0004076	biotin synthase activity	molecular_function	21.47808	20.18409	NA	NA	NA	NA	21.41440	14.40324	22.90684	18.19004	21.21156	20.84266	20.61718	19.14644	21.50232	NA	18.89688	18.50676	20.18475	17.57837	22.00109	16.37646	21.38891	22.53933	1.293986	0.0113906	0.0268747
GO:0019213	deacetylase activity	molecular_function	26.26293	24.96734	26.30477	23.71596	23.89380	24.18422	24.63646	25.08619	26.17015	25.74449	26.75852	25.47145	26.03044	24.64470	25.93062	24.07306	26.51176	25.22303	26.91624	25.04881	27.39935	24.67866	25.26509	25.42437	1.295592	0.0055332	0.0149198
GO:0008712	ADP-glyceromanno-heptose 6-epimerase activity	molecular_function	23.85529	22.55928	20.98359	NA	NA	NA	23.96980	23.18420	24.02703	23.80594	24.60169	21.48817	23.72391	21.37324	23.80444	22.43781	23.71136	22.35307	23.64804	20.96310	23.76843	20.91407	24.32581	23.35257	1.296005	0.0071521	0.0184786
GO:0008676	3-deoxy-8-phosphooctulonate synthase activity	molecular_function	23.48321	22.18158	NA	NA	NA	NA	23.05507	21.66355	23.32169	22.85036	23.75119	21.11342	22.63778	20.86870	23.26156	21.62873	24.68044	23.04372	22.37986	22.89057	23.25396	21.43475	23.66326	22.32237	1.301628	0.0014238	0.0048313
GO:0010035	response to inorganic substance	biological_process	27.58251	26.28075	26.56615	24.37395	25.94792	25.81685	27.52580	26.80734	27.30295	26.48284	27.65629	26.48790	27.60923	25.99097	27.39766	26.10822	28.46536	26.53269	27.96384	26.60107	27.84326	26.49124	27.72358	26.22366	1.301761	0.0002411	0.0012605
GO:0015595	spermidine-importing ATPase activity	molecular_function	22.81610	21.50248	21.43111	20.90491	21.24467	21.46293	22.70134	20.31055	22.96316	21.99628	23.05844	21.43721	23.05900	21.87506	23.58605	18.76791	21.31098	22.45835	23.21346	21.08640	22.87617	21.38632	23.36838	22.09490	1.313622	0.0028911	0.0086830
GO:0008861	formate C-acetyltransferase activity	molecular_function	28.78629	27.46855	28.83108	25.26919	29.17977	28.21286	28.61330	27.13877	28.16926	27.69571	28.23540	25.72769	28.81872	27.75918	27.55739	27.30991	29.73221	27.83826	29.11933	27.74831	28.88198	27.47627	28.33085	27.74499	1.317748	0.0003672	0.0017002
GO:0016153	urocanate hydratase activity	molecular_function	27.29969	25.97991	27.77621	26.07787	27.73961	25.14561	26.90288	26.46944	27.56543	25.21796	26.91648	25.39287	27.28742	23.54616	27.02919	22.56587	27.06122	28.03843	26.73879	26.39278	27.03950	20.45366	27.72464	25.84700	1.319779	0.0023728	0.0073705
GO:0016999	antibiotic metabolic process	biological_process	30.30423	28.97699	29.26108	28.52134	29.06369	28.40304	30.20252	29.24329	30.56220	28.75666	30.30322	28.88821	30.60049	28.73726	30.00549	28.46210	30.85499	29.95856	30.19171	28.89303	30.67125	28.42050	30.61931	29.51588	1.327242	0.0000126	0.0002307
GO:0015154	disaccharide transmembrane transporter activity	molecular_function	23.03404	21.70466	24.12829	22.31334	22.46677	20.50644	23.40439	21.34479	23.00255	19.39402	22.48612	21.38683	22.54911	23.90375	22.83003	18.64842	23.39350	21.36189	22.04864	20.65198	22.68777	21.17520	23.14205	20.92056	1.329384	0.0005072	0.0021618
GO:0008935	1,4-dihydroxy-2-naphthoyl-CoA synthase activity	molecular_function	22.56031	21.23072	20.45276	NA	21.83947	20.26710	21.51994	21.61158	23.22863	21.79932	22.37532	20.93074	20.99649	19.76875	21.82924	21.64596	22.95895	21.25999	23.05973	20.05531	23.94183	20.26629	22.45268	22.37966	1.329596	0.0081274	0.0204161
GO:0004355	glutamate synthase (NADPH) activity	molecular_function	24.29683	22.96515	23.99506	19.87308	NA	NA	22.97892	22.89552	24.21158	24.50684	24.27036	22.23546	24.45632	21.76411	23.01301	21.60102	24.41789	23.21536	25.02738	23.01055	25.28681	21.31146	23.56619	24.00276	1.331684	0.0032952	0.0097416
GO:0071616	acyl-CoA biosynthetic process	biological_process	28.00569	26.67302	27.09412	25.54038	27.40432	27.06753	27.76572	26.52710	28.51708	26.66942	28.16143	26.26119	28.40036	26.94433	27.45675	26.49846	27.94556	26.88837	28.02578	26.74065	28.39771	26.82784	28.19405	26.88872	1.332664	0.0000010	0.0000515
GO:1901565	organonitrogen compound catabolic process	biological_process	32.05272	30.71516	32.05518	30.47665	32.17158	30.70120	31.74241	30.82358	32.31558	30.31214	31.89231	30.27141	32.36322	30.25564	31.64290	29.92134	32.22675	32.12521	31.66022	31.23275	32.09672	29.32282	32.18690	30.42610	1.337559	0.0000025	0.0000823
GO:0004335	galactokinase activity	molecular_function	24.00954	22.66992	21.05465	20.99433	24.73704	20.81883	23.78071	21.49137	24.34343	20.71502	24.02868	23.61634	24.49308	24.54294	23.66930	21.71656	24.75904	21.50304	21.77958	21.39027	23.74989	23.96551	24.23654	20.89127	1.339620	0.0053048	0.0144186
GO:0008804	carbamate kinase activity	molecular_function	26.24854	24.90513	27.34621	24.70034	26.95432	24.77175	25.01327	25.21524	25.79319	24.93610	26.58422	25.60676	26.83208	25.17752	24.45502	24.06217	25.96528	24.85334	26.39366	25.52557	25.62662	22.15537	25.09166	24.77975	1.343407	0.0037761	0.0108587
GO:1901606	alpha-amino acid catabolic process	biological_process	31.16267	29.81149	31.38427	29.36029	31.58478	30.11464	30.66382	29.86127	31.24186	29.63200	30.96416	29.39826	31.41515	29.66964	30.66076	28.98844	31.40097	30.81268	31.17252	30.62679	30.90429	28.09463	31.07136	29.54010	1.351187	0.0000058	0.0001363
GO:0006631	fatty acid metabolic process	biological_process	29.75348	28.39942	28.26629	27.66432	27.69353	27.60904	29.75162	28.77608	30.28289	28.76097	30.14999	28.03078	30.36904	28.49131	29.84160	28.48663	29.97509	29.04178	29.00267	27.98581	29.71087	28.32441	30.15262	28.50289	1.354054	0.0005327	0.0022379
GO:0006085	acetyl-CoA biosynthetic process	biological_process	27.73488	26.37261	26.95036	25.13301	27.23514	26.84088	27.38160	26.26854	28.32484	26.52561	27.81057	25.91982	28.24306	26.47229	27.04623	26.19777	27.68622	26.58043	27.62883	26.46811	28.20177	26.38724	27.80469	26.67030	1.362271	0.0000014	0.0000594
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	molecular_function	30.40820	29.03918	28.41564	28.26702	28.54003	28.87488	30.74410	28.37295	31.36630	28.82384	30.39352	28.65227	31.13112	29.50886	30.44547	29.23703	29.96525	29.75504	28.35626	29.08023	30.24224	29.21077	31.20332	28.94436	1.369028	0.0073151	0.0187393
GO:0044282	small molecule catabolic process	biological_process	31.95188	30.58140	31.80946	30.21589	32.07984	30.74459	31.64229	30.59874	32.21416	30.24896	31.84154	30.11591	32.25652	30.37759	31.53965	29.82080	32.24319	31.80322	31.67271	31.10440	31.91191	29.59762	32.03812	30.32997	1.370480	0.0000004	0.0000273
GO:0009246	enterobacterial common antigen biosynthetic process	biological_process	21.09637	19.72123	21.08827	16.23913	NA	16.94987	20.92580	18.80779	21.00406	17.52004	21.56195	19.66318	20.20036	20.55766	18.39092	20.33630	21.65340	19.87642	NA	NA	21.38967	21.30592	21.59295	19.04283	1.375139	0.0109299	0.0260821
GO:0044434	chloroplast part	cellular_component	25.65199	24.27045	23.51010	22.07170	23.14797	23.65673	25.55873	24.39097	25.08799	24.10231	25.86421	23.87062	25.94757	24.47827	25.42118	24.35548	26.24402	24.72490	26.59612	24.28006	26.10864	24.02994	25.56512	25.23729	1.381539	0.0058265	0.0156023
GO:0044435	plastid part	cellular_component	26.65291	25.27045	24.55428	23.07170	24.14797	24.65673	26.55873	25.39097	26.08799	25.10231	26.86421	24.87062	26.94757	25.47827	26.42118	25.35548	27.24402	25.72490	27.59612	25.28006	27.10864	25.02994	26.56512	26.23729	1.382463	0.0055222	0.0149050
GO:0008765	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	molecular_function	22.86752	21.48346	19.68311	18.99291	NA	19.38013	23.10236	20.38258	22.13720	21.77801	23.38104	20.51076	21.23450	20.30949	23.59111	22.38846	22.29577	21.25899	21.31839	22.54573	22.87924	19.81262	24.29327	22.97563	1.384060	0.0236752	0.0478789
GO:0051262	protein tetramerization	biological_process	25.36012	23.96823	23.54627	22.54840	23.58010	23.86316	24.21147	22.73443	24.83414	23.62217	26.83144	25.73979	24.76230	23.93649	24.74479	23.33618	27.00790	24.13661	25.18689	21.23218	24.89103	24.89534	24.20746	22.08722	1.391891	0.0119171	0.0277793
GO:0008780	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity	molecular_function	21.71532	20.31820	19.06780	NA	NA	NA	20.68381	20.21698	21.00243	21.26578	22.54699	18.17650	21.55545	19.89570	21.93068	20.58633	21.61757	20.52126	20.80424	19.14210	22.53339	19.90074	22.46029	21.01395	1.397119	0.0111588	0.0264647
GO:0006740	NADPH regeneration	biological_process	23.43248	22.03499	21.60312	21.70717	22.17517	21.15401	22.79464	22.01085	22.05807	22.24517	24.22294	20.77166	22.23895	21.07292	22.98762	20.71539	22.48733	23.16489	25.29197	21.28573	23.67363	19.36570	23.48940	23.73496	1.397482	0.0083371	0.0208851
GO:0042242	cobyrinic acid a,c-diamide synthase activity	molecular_function	20.71808	19.31894	NA	NA	NA	NA	22.41307	19.34605	20.01708	20.23976	21.05652	19.27059	19.09030	18.78807	20.03003	17.83637	20.10070	18.60285	NA	NA	19.46389	16.91286	20.51280	20.50379	1.399142	0.0247292	0.0496045
GO:0071248	cellular response to metal ion	biological_process	22.31871	20.91745	20.17294	18.65596	20.37169	21.07880	22.14203	20.68521	22.50459	21.53202	23.74087	19.59811	19.69790	20.17057	22.05195	20.54751	23.46071	21.15925	22.13099	20.76141	21.31545	19.59124	22.62333	22.52225	1.401259	0.0218193	0.0450303
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	molecular_function	27.42849	26.00652	26.63447	25.54691	26.02227	24.55584	27.39149	25.87745	26.75977	26.89126	28.20293	25.62875	27.51582	25.74017	26.34502	25.67279	26.11787	25.82046	28.53677	25.36503	27.12021	25.78688	28.30096	27.25309	1.421973	0.0008843	0.0032650
GO:0004611	phosphoenolpyruvate carboxykinase activity	molecular_function	27.36499	25.92083	26.22411	24.84754	25.10098	25.69239	27.87725	25.19953	27.02652	25.25900	27.31114	26.09024	27.04523	26.77717	26.63463	26.13057	27.27354	25.69533	28.51672	25.55827	28.04741	26.31706	27.34855	26.39789	1.444165	0.0007570	0.0028698
GO:0008776	acetate kinase activity	molecular_function	27.32777	25.87274	26.59528	24.60689	25.46561	25.07207	27.17511	26.09407	28.20403	26.34007	27.50533	25.34325	28.00108	26.26238	26.84636	26.02502	26.69385	26.11057	26.94073	26.09371	27.69822	25.23866	27.64282	26.31468	1.455035	0.0001343	0.0008336
GO:0004157	dihydropyrimidinase activity	molecular_function	20.02224	18.55939	20.35019	17.62149	NA	NA	NA	NA	18.38395	20.40185	20.60093	18.67457	19.45685	NA	18.67736	14.86703	19.44586	17.04734	19.90600	15.88981	21.24137	15.92873	19.93187	19.60347	1.462851	0.0065536	0.0170947
GO:0015594	putrescine-importing ATPase activity	molecular_function	22.79241	21.32765	21.43111	20.90491	20.88347	21.46293	22.70134	20.31055	22.96316	21.99628	23.00899	21.43721	23.01959	21.61726	23.58605	18.76791	21.16941	21.34435	23.21346	21.08640	22.87617	21.38632	23.36838	22.09490	1.464757	0.0017244	0.0056401
GO:0051539	4 iron, 4 sulfur cluster binding	molecular_function	28.82705	27.35839	27.42277	24.48052	26.70009	26.00097	28.93034	27.67153	29.46774	27.38507	28.87549	26.69105	29.68653	27.70584	28.82126	27.67599	28.26427	27.98315	27.95746	26.94761	29.19167	27.08652	29.31614	28.31591	1.468652	0.0020422	0.0064319
GO:0005507	copper ion binding	molecular_function	22.90990	21.42405	21.86411	20.78994	20.19666	22.59142	22.07442	21.34399	21.93654	19.43680	23.51091	22.08275	24.00184	22.41753	22.65964	20.95603	23.19470	21.52648	22.80280	19.23834	23.42091	21.59702	23.21153	19.08780	1.485852	0.0038463	0.0110161
GO:0008519	ammonium transmembrane transporter activity	molecular_function	24.12014	22.63309	22.74419	21.93614	22.79976	22.46293	23.71355	21.74164	24.29845	23.10344	24.69894	22.79770	24.33025	23.33224	24.72454	20.67306	23.72904	23.18092	24.37341	22.08640	24.01980	22.38632	24.46532	23.29224	1.487053	0.0001142	0.0007550
GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	molecular_function	20.18341	18.69034	18.85248	17.94432	NA	18.30980	20.80121	17.43666	NA	NA	21.08270	17.46237	19.04343	18.92687	18.13732	19.38699	19.53245	18.50921	20.73411	18.50936	20.29714	19.94639	20.58749	18.43516	1.493073	0.0037636	0.0108388
GO:0015101	organic cation transmembrane transporter activity	molecular_function	24.01920	22.51647	22.58274	21.90491	22.07534	22.46293	23.71355	21.74164	24.29845	23.10344	24.58942	22.58927	24.03943	22.75191	24.72454	20.67306	23.22713	23.02199	24.37341	22.08640	24.01980	22.38632	24.46532	23.29224	1.502733	0.0003826	0.0017537
GO:0050480	imidazolonepropionase activity	molecular_function	24.61891	23.11532	25.31623	22.93565	24.25850	21.65216	24.84759	23.06889	24.73543	21.93744	24.24201	22.60053	24.30300	22.31106	23.99529	20.02026	24.24392	25.53861	23.24088	22.74857	25.35811	15.66847	24.99311	22.81012	1.503588	0.0031088	0.0092447
GO:0004416	hydroxyacylglutathione hydrolase activity	molecular_function	19.69166	18.18717	18.87316	NA	19.70286	NA	19.66367	NA	20.69047	18.56350	20.40746	NA	18.67557	NA	19.69371	17.83173	17.57605	19.00557	19.10799	16.45260	NA	NA	20.18708	17.96348	1.504490	0.0123093	0.0284980
GO:0016831	carboxy-lyase activity	molecular_function	30.16544	28.65300	28.80818	25.34820	26.15983	26.30266	30.03752	29.09671	30.51492	29.51948	30.49931	27.61636	29.86783	28.49412	29.93020	29.18561	31.14353	28.46190	30.73242	28.36480	30.15538	27.67088	30.15139	29.96833	1.512438	0.0110198	0.0262046
GO:0050308	sugar-phosphatase activity	molecular_function	25.43012	23.90919	21.97053	22.31064	23.58477	22.51264	25.89179	24.36380	24.82006	24.08102	25.82755	23.85209	25.20676	24.18007	25.21244	23.61847	25.14576	23.98926	26.39458	24.31260	26.11243	23.38694	25.67830	24.70151	1.520933	0.0079404	0.0200390
GO:0009063	cellular amino acid catabolic process	biological_process	31.70229	30.17763	31.72317	29.82541	31.90103	30.36371	31.37111	30.26216	31.99206	29.88291	31.50545	29.70042	32.05189	29.80312	31.30622	29.10931	31.73883	31.48048	31.40416	30.88744	31.71473	28.44951	31.79476	29.91256	1.524665	0.0000016	0.0000608
GO:0033387	putrescine biosynthetic process from ornithine	biological_process	25.05318	23.52722	24.74108	16.15934	NA	NA	24.81957	24.23943	24.16095	24.16547	25.64339	20.71964	23.50707	22.76489	25.80426	24.73499	22.45106	19.84196	26.44469	21.51688	23.61098	NA	25.21415	24.80879	1.525960	0.0207349	0.0432520
GO:0009055	electron transfer activity	molecular_function	30.05011	28.51616	27.79783	27.56211	26.75276	28.21948	30.08046	28.79719	30.75207	28.68477	30.68169	28.26585	30.76552	28.86243	30.09070	28.24383	29.78993	29.26140	28.92237	28.09916	30.23594	28.27387	30.52578	28.67971	1.533951	0.0088085	0.0218845
GO:0006596	polyamine biosynthetic process	biological_process	26.32175	24.78303	25.87372	20.30085	21.22984	19.69717	26.12091	25.76751	26.34767	25.68691	27.02917	23.48658	25.00636	25.07809	26.93005	25.91383	25.83469	23.17114	27.63902	23.01429	25.29982	21.87021	26.44927	26.10430	1.538711	0.0210712	0.0437856
GO:0006547	histidine metabolic process	biological_process	29.28765	27.74220	29.42736	27.84449	29.30816	26.87497	28.96252	28.03819	29.64443	26.90674	29.10978	27.17158	29.54247	26.09862	28.82548	24.96838	29.04793	29.75598	28.42789	28.22171	29.65605	24.38287	29.68076	27.62270	1.545445	0.0001906	0.0010723
GO:0019294	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	biological_process	23.48924	21.94084	NA	NA	NA	NA	23.05507	21.66355	23.32169	22.85036	23.75119	21.11342	22.63778	20.86870	23.26156	21.62873	24.70399	23.05898	22.37986	20.07459	23.25396	21.43475	23.66326	22.32237	1.548407	0.0005764	0.0023663
GO:0006567	threonine catabolic process	biological_process	28.27564	26.72679	27.55973	24.63656	28.32887	27.65707	27.82044	26.39154	27.29746	26.62627	27.92639	24.98256	28.32824	26.79418	27.19651	26.38928	29.83863	27.41304	28.63097	26.99478	28.17985	26.33883	27.65740	27.23168	1.548854	0.0003048	0.0015111
GO:0009376	HslUV protease complex	cellular_component	23.45020	21.90108	21.40662	18.09783	22.31291	21.77176	22.64364	19.76648	20.56696	20.87187	24.09641	18.69795	21.79370	21.00988	23.23612	23.26017	25.13304	23.88278	24.23020	19.69107	23.63111	21.42037	23.10993	22.16542	1.549124	0.0092045	0.0226150
GO:0019557	histidine catabolic process to glutamate and formate	biological_process	28.25568	26.69648	28.43883	26.85424	28.28711	25.82932	27.92555	27.04234	28.62215	25.85688	28.06445	26.07022	28.47626	24.41465	27.79053	23.39317	28.00641	28.75501	27.42104	27.18684	28.62364	21.79061	28.63413	26.61932	1.559204	0.0006714	0.0026680
GO:0009446	putrescine biosynthetic process	biological_process	25.08860	23.52600	24.74108	16.15934	NA	14.86991	24.98271	24.91045	24.16095	24.16547	25.64339	20.71964	23.50707	22.76489	25.80426	24.73499	23.37030	20.15616	26.44469	21.51688	23.61098	NA	25.21415	24.80879	1.562599	0.0130935	0.0298308
GO:0009445	putrescine metabolic process	biological_process	25.08902	23.52600	24.74108	16.15934	NA	14.86991	24.98271	24.91045	24.16095	24.16547	25.64339	20.71964	23.50707	22.76489	25.80426	24.73499	23.38401	20.15616	26.44469	21.51688	23.61098	NA	25.21415	24.80879	1.563017	0.0130499	0.0298064
GO:0009066	aspartate family amino acid metabolic process	biological_process	31.30953	29.74591	29.36156	28.36123	29.85213	29.79622	31.38282	29.23260	31.69446	29.33977	31.09112	29.39863	32.13844	30.24770	31.39230	29.85520	31.73739	30.35988	30.70927	29.47121	31.55976	30.30647	31.48533	29.76539	1.563622	0.0001112	0.0007546
GO:0052803	imidazole-containing compound metabolic process	biological_process	30.27730	28.71295	30.42701	28.83813	30.29427	27.83138	29.95992	29.02401	30.64082	27.87695	30.10498	28.13343	30.51444	26.84011	29.81691	25.68399	30.03417	30.75177	29.41561	29.19463	30.64779	24.78244	30.66563	28.60829	1.564346	0.0003063	0.0015138
GO:0016781	phosphotransferase activity, paired acceptors	molecular_function	25.72451	24.15299	22.05228	23.03184	24.29990	17.83487	26.26971	24.94893	25.99845	24.76077	25.34597	23.68261	25.92708	23.90609	26.52933	23.87945	25.93251	24.27800	24.74287	24.54473	25.50113	22.61001	26.48646	25.24398	1.571518	0.0198729	0.0418394
GO:0009074	aromatic amino acid family catabolic process	biological_process	29.26874	27.68504	29.42694	27.83933	29.28023	26.78733	28.95802	28.01094	29.63720	26.84732	29.10211	27.09711	29.50011	25.53051	28.80895	24.32942	29.02092	29.74765	28.40359	28.17095	29.63948	22.75435	29.65033	27.59445	1.583702	0.0006237	0.0025076
GO:0006548	histidine catabolic process	biological_process	29.26688	27.68310	29.42665	27.83174	29.28023	26.78643	28.95731	28.00969	29.63720	26.84652	29.10016	27.09424	29.48586	25.52494	28.80829	24.32942	29.02028	29.74754	28.40323	28.16703	29.63948	22.73504	29.65033	27.59372	1.583778	0.0006281	0.0025218
GO:0004590	orotidine-5’-phosphate decarboxylase activity	molecular_function	23.47321	21.88231	20.36510	NA	21.72771	21.16819	23.26907	21.90513	23.38855	20.22293	23.96155	20.56299	24.03929	21.64456	23.82437	20.48487	21.52552	20.63372	23.28595	24.12310	22.51825	20.15024	25.04000	21.85475	1.590900	0.0061561	0.0163242
GO:0016054	organic acid catabolic process	biological_process	31.81906	30.22726	31.74246	29.86787	31.92633	30.40159	31.50923	30.33078	32.14264	29.92733	31.67586	29.75293	32.19569	29.85999	31.46413	29.16496	31.91404	31.53523	31.45810	30.91088	31.80873	28.56157	31.94483	29.96571	1.591803	0.0000008	0.0000467
GO:0046336	ethanolamine catabolic process	biological_process	25.65348	24.05921	21.26594	18.04203	NA	19.40710	26.07949	20.30526	24.91147	23.28007	25.55467	20.81911	22.19140	17.73135	24.82251	17.22057	27.59351	27.36352	24.83945	19.76840	24.59565	21.53833	26.27439	19.92509	1.594276	0.0007053	0.0027338
GO:0034310	primary alcohol catabolic process	biological_process	25.65686	24.06229	21.26594	18.04203	NA	19.40710	26.07949	20.30526	24.91147	23.28007	25.59038	21.10896	22.19140	17.73135	24.82251	17.22057	27.59351	27.36352	24.83945	19.76840	24.59565	21.53833	26.27439	19.92509	1.594564	0.0007501	0.0028513
GO:0019556	histidine catabolic process to glutamate and formamide	biological_process	28.23270	26.63411	28.35247	26.75513	28.24041	25.74209	27.92154	26.95503	28.62133	25.80121	28.04637	26.03412	28.47391	24.62479	27.78004	23.26017	27.99150	28.69420	27.34514	27.12451	28.61480	21.67304	28.62407	26.56224	1.598599	0.0006085	0.0024575
GO:0046395	carboxylic acid catabolic process	biological_process	31.81597	30.21651	31.73554	29.84983	31.91391	30.38909	31.50716	30.31057	32.14215	29.91601	31.67477	29.74280	32.19285	29.83716	31.46187	29.15133	31.91118	31.53361	31.45665	30.90585	31.80825	28.54929	31.94413	29.95146	1.599457	0.0000008	0.0000463
GO:0047465	N-acylglucosamine-6-phosphate 2-epimerase activity	molecular_function	21.76026	20.15171	22.39502	17.86600	22.77032	21.26223	21.30540	19.50220	20.32089	NA	21.02648	NA	23.25760	21.67642	20.99068	19.27592	20.95164	18.57289	21.39630	NA	20.07817	17.68285	21.17023	20.23647	1.608559	0.0034553	0.0101093
GO:0042454	ribonucleoside catabolic process	biological_process	24.17852	22.56491	NA	NA	23.80663	22.09257	22.72465	23.03724	NA	NA	25.55482	22.76918	NA	NA	NA	NA	23.54023	22.67357	23.44486	21.05176	24.75254	22.95580	23.27251	NA	1.613605	0.0129416	0.0296838
GO:0042286	glutamate-1-semialdehyde 2,1-aminomutase activity	molecular_function	23.65072	22.03360	19.68440	NA	22.11602	20.04025	24.28691	21.99196	22.88665	22.39228	23.99528	20.71898	22.43818	21.56014	23.50804	21.96222	23.54570	22.25321	24.05907	22.01405	24.12606	20.67229	24.78398	23.56011	1.617121	0.0125385	0.0289055
GO:0004015	adenosylmethionine-8-amino-7-oxononanoate transaminase activity	molecular_function	20.67254	19.03923	NA	NA	19.42334	18.30318	19.80600	17.03108	21.73340	17.90471	19.34225	17.55841	NA	NA	20.26707	NA	20.49453	18.16382	19.34101	20.29444	NA	NA	22.00064	20.30535	1.633304	0.0111813	0.0264729
GO:0006646	phosphatidylethanolamine biosynthetic process	biological_process	19.91937	18.27937	19.77128	NA	NA	NA	20.59019	18.07428	19.08071	18.54942	18.60608	NA	17.91131	17.06619	17.85927	NA	20.94025	18.54749	18.91339	15.30211	19.29063	17.14773	21.44635	19.71644	1.640008	0.0206824	0.0431756
GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity	molecular_function	21.00061	19.36019	NA	NA	19.51682	NA	18.86275	17.49661	21.64384	19.46707	21.23457	17.19819	NA	NA	22.28386	15.83987	20.74061	21.60686	21.37219	15.47583	NA	NA	17.87545	18.42815	1.640420	0.0200464	0.0421091
GO:0016453	C-acetyltransferase activity	molecular_function	29.16346	27.51788	28.83456	25.26944	29.18500	28.21640	29.09671	27.14740	29.04856	27.69908	29.05015	25.76457	29.54869	27.79564	28.37525	27.31074	29.88206	28.14327	29.13697	27.74891	29.04022	27.48448	29.09782	27.76972	1.645589	0.0000087	0.0001813
GO:0009072	aromatic amino acid family metabolic process	biological_process	30.64733	28.98450	30.48827	29.02348	30.33652	28.08379	30.42086	29.20597	30.87031	28.08354	30.54945	28.48836	31.01567	28.22036	30.41708	27.10306	30.15546	30.81064	30.24578	29.30206	30.99753	27.57875	31.18902	28.97986	1.662830	0.0000047	0.0001252
GO:0016748	succinyltransferase activity	molecular_function	24.34831	22.68363	22.74643	22.26987	23.07455	23.02135	24.51168	23.27242	22.81670	22.68891	25.10680	22.55051	22.81266	22.33620	23.80220	22.23458	24.72194	22.64016	25.71330	21.53439	24.48484	22.29817	24.48462	23.57961	1.664681	0.0006044	0.0024518
GO:0015489	putrescine transmembrane transporter activity	molecular_function	23.19472	21.52998	21.71993	20.90491	20.88347	21.46293	22.72567	21.07311	23.57033	22.20319	23.97668	21.72681	23.01959	21.61726	23.85089	20.22497	22.78302	21.39342	23.51738	21.08640	23.15042	21.38632	23.53468	22.46383	1.664737	0.0001651	0.0009752
GO:0004329	formate-tetrahydrofolate ligase activity	molecular_function	26.69099	25.01485	25.37450	24.94414	26.73344	25.30729	26.36229	24.77738	27.34091	24.25086	26.40564	24.02523	26.99944	24.35800	26.52413	23.75765	27.06635	26.72475	25.59965	25.23731	27.15593	23.66675	26.83745	25.01321	1.676144	0.0000139	0.0002447
GO:0008874	gluconate 5-dehydrogenase activity	molecular_function	22.06843	20.39175	22.22641	17.51539	23.79619	20.41028	20.66229	20.51682	20.22397	18.46647	NA	NA	22.45948	22.34223	18.71446	20.94420	22.22669	20.75123	22.07534	18.48280	21.62534	18.54305	21.44892	18.82908	1.676680	0.0104384	0.0251298
GO:0015893	drug transport	biological_process	24.11882	22.43771	22.24937	22.21946	20.08428	19.84069	23.09623	21.38620	25.05489	21.87662	24.71157	22.39861	23.39942	23.50891	24.80701	21.37493	23.73733	23.73627	23.49316	20.61313	24.22483	21.91437	25.14809	23.30465	1.681108	0.0108638	0.0259927
GO:0097171	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	biological_process	24.35871	22.66949	21.25577	16.38930	NA	NA	24.67117	23.24686	24.33570	23.81209	25.09275	22.91510	23.84768	21.37324	24.15270	22.51347	24.36294	22.61769	24.37248	21.00139	24.46704	21.38708	24.77570	23.74429	1.689220	0.0092006	0.0226150
GO:0016840	carbon-nitrogen lyase activity	molecular_function	28.98193	27.28978	27.67965	26.45682	27.25480	26.10819	28.76288	26.92771	29.17228	27.36377	29.18270	27.17408	29.10929	27.41189	28.31415	26.72355	29.98856	28.66352	28.65923	27.35234	29.39810	26.52174	29.33587	27.62037	1.692149	0.0000360	0.0004308
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	molecular_function	21.36231	19.66760	NA	NA	NA	NA	20.80679	21.58946	22.21689	19.46510	21.20144	18.19417	NA	18.06708	21.36435	15.77739	20.96334	18.97739	21.93928	18.33480	20.92013	17.13472	20.69424	20.92761	1.694715	0.0016006	0.0053393
GO:0000050	urea cycle	biological_process	26.64162	24.94513	27.48780	24.59497	27.73569	25.36318	25.68776	24.91445	26.34246	25.68079	26.29780	23.78231	26.68154	24.14740	26.60880	24.51618	25.57128	25.48800	26.95406	25.90105	25.50825	20.07364	26.26668	25.00127	1.696492	0.0013981	0.0047620
GO:0015689	molybdate ion transport	biological_process	21.98315	20.28139	19.98113	NA	NA	NA	22.65809	NA	20.45928	20.60935	22.17451	16.86758	NA	NA	21.54250	18.47944	21.72831	19.93061	22.24240	19.09011	23.07050	17.02498	21.60163	22.29483	1.701752	0.0043422	0.0121796
GO:0030076	light-harvesting complex	cellular_component	25.01367	23.31100	23.20877	22.60906	20.60995	21.32341	25.52052	22.52194	25.41731	23.35505	24.75099	23.11795	25.74264	23.76802	25.07722	22.96468	24.11167	24.45874	23.07891	21.53963	26.07192	24.31103	25.60594	23.28287	1.702668	0.0204456	0.0428789
GO:0004586	ornithine decarboxylase activity	molecular_function	27.48195	25.77745	26.46185	16.52659	NA	NA	26.72847	26.96230	26.73572	26.76352	28.29477	21.94307	25.92596	24.90968	27.79417	27.24545	27.35962	21.96581	28.88891	24.75169	25.91826	19.36712	27.58016	26.61383	1.704497	0.0096374	0.0234507
GO:0018801	glutaconyl-CoA decarboxylase activity	molecular_function	28.27147	26.56688	26.44403	19.19929	NA	NA	28.60765	26.95603	28.69334	27.79224	28.51170	23.61191	28.80306	24.94681	27.95954	26.70157	28.23853	26.84320	26.35769	25.86975	28.29371	25.09439	28.78298	27.94860	1.704587	0.0084136	0.0209992
GO:0009095	aromatic amino acid family biosynthetic process, prephenate pathway	biological_process	22.45853	20.74904	20.12236	19.32816	NA	18.73124	22.24971	18.92719	22.31396	19.88968	22.85560	22.40151	21.83930	19.54372	21.87151	20.05349	23.63462	21.09758	22.76765	18.29502	21.98582	21.39722	22.69648	21.96793	1.709496	0.0007046	0.0027338
GO:0030523	dihydrolipoamide S-acyltransferase activity	molecular_function	25.42563	23.71541	23.36394	21.88927	24.82613	24.77217	25.06147	23.02649	22.83939	22.73648	26.14756	23.10153	25.95269	22.61350	24.01006	22.12787	25.67833	23.10055	25.64250	22.34874	25.84327	25.07832	26.42739	25.00536	1.710220	0.0016677	0.0055010
GO:0019464	glycine decarboxylation via glycine cleavage system	biological_process	24.16018	22.44792	20.74783	18.73743	25.80369	25.34020	21.45141	18.10436	22.83075	18.75727	23.44213	21.53130	20.74736	17.07510	21.57164	18.86448	26.16063	22.60586	24.66452	21.69979	23.70245	21.85567	21.94287	20.97730	1.712258	0.0143602	0.0319926
GO:0004070	aspartate carbamoyltransferase activity	molecular_function	26.63147	24.91906	26.43149	23.01531	23.92594	24.62050	26.13857	24.77582	26.25752	26.04423	27.16773	25.08324	26.86137	24.25083	25.95777	23.77463	27.26350	25.70079	27.14079	25.32247	27.37301	22.47427	25.89183	25.40986	1.712410	0.0006599	0.0026300
GO:0008785	alkyl hydroperoxide reductase activity	molecular_function	23.12635	21.41053	21.83869	19.49183	24.33021	23.46175	22.69227	17.49506	23.48388	15.96869	22.30902	21.66240	22.73696	21.27131	22.33876	20.75731	23.16213	22.14104	22.51300	20.76938	23.64788	21.82916	23.43779	18.46682	1.715822	0.0012462	0.0043094
GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity	molecular_function	25.38843	23.66130	23.36394	21.88927	24.35973	24.48837	25.06147	23.02649	22.83939	22.73648	26.14277	23.07576	25.95269	22.61350	24.01006	22.12787	25.67833	23.10055	25.58318	22.28846	25.79332	25.07493	26.42739	25.00536	1.727129	0.0017075	0.0056035
GO:0015942	formate metabolic process	biological_process	28.50044	26.77061	28.46503	26.85424	28.28721	25.83335	28.23110	27.04469	28.66329	25.89450	28.39358	26.09488	28.52679	24.50432	28.18440	23.40540	28.62154	28.81858	28.00109	27.19324	28.79879	22.21625	29.02393	27.05149	1.729835	0.0002344	0.0012373
GO:0033468	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	biological_process	22.04977	20.31488	21.08130	NA	NA	NA	21.42093	19.65300	21.93934	20.92214	23.02807	20.63565	21.75472	18.51734	22.41958	19.82413	21.41384	21.25881	22.24093	18.39747	22.00145	17.62278	22.16924	21.48676	1.734891	0.0003222	0.0015637
GO:0016846	carbon-sulfur lyase activity	molecular_function	27.33184	25.59639	25.09352	25.33556	24.88768	24.77316	28.45988	25.50182	28.85890	25.94799	27.40067	25.67601	28.15753	26.53957	26.98905	25.41297	25.43745	26.10346	25.64978	25.28566	26.89207	25.41984	26.61659	24.32877	1.735455	0.0104154	0.0250967
GO:0008817	cob(I)yrinic acid a,c-diamide adenosyltransferase activity	molecular_function	26.39589	24.65748	24.41822	21.92649	NA	18.65793	28.26991	24.75671	26.79884	25.96196	25.12635	24.06389	24.80236	24.59832	25.89837	23.78098	26.04733	26.40634	25.38555	23.25661	26.23166	22.22101	26.57178	24.92174	1.738409	0.0079224	0.0200121
GO:0019206	nucleoside kinase activity	molecular_function	23.86917	22.13059	23.36258	21.41584	22.87252	22.24108	24.95148	21.05244	22.25314	20.42770	24.10847	22.42313	21.22672	22.14482	24.25641	NA	21.11975	22.07511	23.88339	21.65465	24.66879	22.93338	24.72004	23.03349	1.738584	0.0085547	0.0213122
GO:0010039	response to iron ion	biological_process	25.32190	23.57983	24.79715	21.36395	24.09099	22.17866	25.71102	22.62878	24.19953	22.72862	25.04495	20.36688	24.58481	23.16300	25.23155	22.96562	24.91305	22.40753	26.22258	25.81896	26.20665	22.68388	25.67666	24.66534	1.742073	0.0001248	0.0007979
GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	molecular_function	25.28661	23.52781	21.03347	20.75851	23.50113	22.33165	25.80811	24.05056	24.80558	23.95457	25.77057	23.48159	25.09171	23.47599	25.06173	23.39371	24.68560	23.31299	26.19856	24.14257	25.97876	21.87973	25.57485	24.58405	1.758809	0.0081213	0.0204161
GO:1901160	primary amino compound metabolic process	biological_process	27.23668	25.46453	24.13161	22.05272	18.42735	20.40710	28.71689	23.20595	27.20526	25.44745	26.67755	23.21636	23.89287	19.39054	26.55305	21.35824	28.80626	28.64460	26.34890	21.45210	26.67495	22.84686	27.84762	22.24015	1.772149	0.0130821	0.0298299
GO:0006558	L-phenylalanine metabolic process	biological_process	22.71822	20.93202	19.88200	19.98395	NA	18.45115	22.21558	18.83571	20.88852	19.54263	23.03056	21.40440	23.89268	17.60736	22.01051	19.85772	23.94584	23.12487	22.69819	17.24868	21.88642	21.00405	22.52040	21.94905	1.786195	0.0027214	0.0082277
GO:0034399	nuclear periphery	cellular_component	22.33600	20.54622	19.93426	17.82994	20.32031	19.50639	22.74182	19.64406	22.57615	21.09566	23.19847	18.71457	22.06530	19.33379	22.57255	19.32826	23.69276	22.36276	20.91401	17.13487	21.98218	20.47221	21.37989	21.95449	1.789772	0.0017450	0.0056801
GO:0015413	nickel-transporting ATPase activity	molecular_function	22.46109	20.66130	20.70693	20.04723	20.80161	20.81000	23.13501	20.71117	21.74488	20.17308	22.40376	21.01560	23.16628	21.37755	23.26928	19.54915	20.59090	21.27310	20.34811	21.02946	23.43583	20.60125	22.91576	19.05304	1.799792	0.0020125	0.0063679
GO:0015157	oligosaccharide transmembrane transporter activity	molecular_function	23.66537	21.86337	24.17844	22.47942	22.46677	20.50644	24.34345	21.66781	23.97422	19.64882	23.07815	21.65885	23.04682	23.90468	23.75661	19.36150	24.31774	22.09469	22.04864	20.65198	23.34472	21.34806	23.94957	20.92614	1.802006	0.0000952	0.0006922
GO:0072380	TRC complex	cellular_component	22.04779	20.24539	19.93426	17.82994	19.37168	19.09554	NA	19.64406	21.80785	20.38299	23.12618	18.71457	22.01332	19.31469	22.54548	19.21598	23.53083	22.33606	20.91401	17.13487	20.78217	20.47221	21.30762	21.00805	1.802400	0.0044956	0.0125451
GO:0008690	3-deoxy-manno-octulosonate cytidylyltransferase activity	molecular_function	22.13244	20.32572	21.08130	NA	NA	NA	21.42093	19.65300	21.93934	20.92214	23.02807	20.63565	21.75472	18.51734	22.41958	19.82413	22.27165	21.30883	22.24093	18.39747	22.00145	17.62278	22.25555	21.48676	1.806715	0.0002119	0.0011470
GO:0042816	vitamin B6 metabolic process	biological_process	26.78208	24.96786	22.18924	23.09145	24.55865	24.35869	26.93965	24.20969	27.59918	24.82815	26.42295	24.80811	27.49893	25.88661	26.72808	24.92651	27.93762	25.93989	24.96993	23.02744	26.88179	25.47216	26.62481	25.20071	1.814224	0.0184807	0.0393965
GO:0042819	vitamin B6 biosynthetic process	biological_process	25.78208	23.96786	21.18924	22.09145	23.55865	23.35869	25.93965	23.20969	26.59918	23.82815	25.42295	23.80811	26.49893	24.88661	25.72808	23.92651	26.93762	24.93989	23.96993	22.02744	25.88179	24.47216	25.62481	24.20071	1.814224	0.0184807	0.0393965
GO:0048038	quinone binding	molecular_function	23.00202	21.18208	NA	NA	NA	NA	22.01446	16.82324	19.33273	16.45419	22.38218	14.97974	20.28967	18.21992	22.98872	NA	25.35249	23.55446	21.45582	NA	21.29496	NA	22.80829	20.42984	1.819942	0.0129881	0.0297153
GO:0008912	lactaldehyde reductase activity	molecular_function	23.82392	22.00217	19.02109	NA	NA	NA	23.69630	21.98338	24.23336	23.74056	24.01872	17.89991	24.85343	20.65860	23.82098	21.77192	23.18638	21.58235	23.52942	19.97884	24.07554	18.65266	23.65272	23.19117	1.821748	0.0102255	0.0246610
GO:0033281	TAT protein transport complex	cellular_component	22.19443	20.35217	NA	NA	NA	NA	21.72121	17.26542	19.51436	20.53431	22.83174	19.03860	21.71362	17.37639	21.46332	20.37062	21.56817	19.82024	23.19653	17.99142	22.40583	NA	22.72110	22.46291	1.842259	0.0027146	0.0082163
GO:0043953	protein transport by the Tat complex	biological_process	22.19443	20.35217	NA	NA	NA	NA	21.72121	17.26542	19.51436	20.53431	22.83174	19.03860	21.71362	17.37639	21.46332	20.37062	21.56817	19.82024	23.19653	17.99142	22.40583	NA	22.72110	22.46291	1.842259	0.0027146	0.0082163
GO:0006051	N-acetylmannosamine metabolic process	biological_process	21.86330	20.01384	22.39502	17.86600	22.77032	21.26223	21.30540	19.50220	20.51052	NA	21.30567	NA	23.24891	21.69477	21.07725	19.29946	20.95164	18.57289	21.61692	15.19472	20.61748	17.68285	21.77397	20.36870	1.849461	0.0013058	0.0044857
GO:0034308	primary alcohol metabolic process	biological_process	27.38945	25.53537	24.13161	22.05272	18.42735	20.40710	28.71344	23.20489	27.20044	25.44745	26.72218	23.33336	23.90901	19.39054	26.55305	21.35824	29.29484	28.72638	26.36903	21.45210	26.69121	22.84686	27.85194	22.33647	1.854072	0.0134836	0.0305149
GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	molecular_function	26.95986	25.09674	25.31881	23.74540	23.92651	23.74373	26.82626	24.99267	25.83433	25.49546	28.02185	25.22669	26.22448	25.26981	26.35480	25.16495	27.34312	24.86330	28.18128	24.86648	27.17519	24.47481	27.02257	26.32624	1.863120	0.0011775	0.0041083
GO:0005654	nucleoplasm	cellular_component	20.95687	19.07677	NA	NA	NA	NA	20.91544	18.82605	21.75230	15.63548	21.05747	18.45874	19.61008	17.41342	19.05275	19.13597	21.49154	20.70673	NA	NA	20.69971	NA	21.30717	19.02275	1.880104	0.0043230	0.0121385
GO:0030412	formimidoyltetrahydrofolate cyclodeaminase activity	molecular_function	24.25692	22.35169	24.38435	22.58125	23.60693	18.71239	23.36307	22.76190	24.06421	19.06318	24.87895	21.75138	25.56994	18.79766	23.84935	20.02010	23.97748	24.95653	22.80843	21.20809	23.88111	16.54905	24.41879	22.06334	1.905234	0.0002887	0.0014506
GO:0010181	FMN binding	molecular_function	27.97437	26.06587	25.59592	25.04382	24.98965	23.95800	27.20822	25.89086	29.16199	25.47137	28.29208	26.95473	28.40771	25.12457	28.24876	24.64035	28.13819	27.24412	25.91382	25.91553	28.20769	27.05156	28.53402	25.81170	1.908501	0.0028153	0.0084833
GO:0004775	succinate-CoA ligase (ADP-forming) activity	molecular_function	24.24403	22.33113	19.63542	16.02495	26.14116	25.18376	22.24347	19.22626	22.28630	17.64780	23.50547	20.94000	21.02030	20.26348	19.64795	20.50564	25.24298	20.00693	24.87933	21.85100	25.21520	21.54170	23.14549	22.60849	1.912895	0.0230632	0.0468154
GO:0044463	cell projection part	cellular_component	24.23066	22.31607	NA	NA	NA	NA	23.19796	19.44797	25.11687	NA	24.47799	18.66944	23.83809	21.08941	22.79700	22.70507	25.68039	23.50040	NA	NA	22.07312	23.14292	22.86559	NA	1.914591	0.0206021	0.0431074
GO:0030409	glutamate formimidoyltransferase activity	molecular_function	26.86801	24.95016	27.00235	25.04621	26.53793	24.61248	26.56475	25.45257	26.91261	24.43872	26.53154	23.22119	26.88686	22.62544	26.99029	22.10976	27.21618	26.96895	25.78855	25.19546	27.43502	18.43871	27.06198	25.12914	1.917851	0.0005513	0.0022871
GO:0005542	folic acid binding	molecular_function	26.87092	24.95103	27.00235	25.04621	26.53018	24.61017	26.56835	25.45285	26.91261	24.43872	26.53514	23.22119	26.88686	22.62544	26.99029	22.10976	27.24086	26.97166	25.79022	25.19546	27.43502	18.43871	27.06198	25.12914	1.919895	0.0005486	0.0022836
GO:0008235	metalloexopeptidase activity	molecular_function	26.25050	24.32899	25.72615	23.78796	25.11796	25.17967	26.36799	23.31882	26.77072	23.13053	27.25463	23.76888	25.97259	24.78973	26.16136	23.70571	26.22718	24.95355	24.68012	24.22575	26.05003	23.79058	26.70259	25.10487	1.921508	0.0000048	0.0001252
GO:0000906	6,7-dimethyl-8-ribityllumazine synthase activity	molecular_function	23.45867	21.52965	20.39933	NA	NA	NA	23.47038	21.51820	24.09669	21.83432	23.39915	20.41968	22.42566	20.26510	23.53781	20.70808	23.38629	22.43755	23.54153	20.08340	23.57174	19.44876	24.24049	23.03946	1.929021	0.0008408	0.0031393
GO:0048029	monosaccharide binding	molecular_function	24.27171	22.34030	23.26694	22.40769	24.45775	20.69651	23.83777	22.20917	24.39771	22.07824	24.21610	22.98587	24.84722	23.08286	23.75377	22.11249	25.39927	22.70528	22.84520	21.67486	24.32621	20.89891	23.92496	22.93209	1.931417	0.0000065	0.0001492
GO:0009349	riboflavin synthase complex	cellular_component	23.53057	21.58164	20.39933	NA	NA	NA	23.47389	21.56785	24.10618	21.90907	23.39915	20.41968	22.42566	20.26510	23.57261	20.77620	23.91590	22.56584	23.54153	20.08340	23.57174	19.44876	24.28239	23.05359	1.948927	0.0009363	0.0034251
GO:0042823	pyridoxal phosphate biosynthetic process	biological_process	25.55569	23.59333	20.31120	22.04125	23.54722	23.16489	25.56581	22.96848	26.42983	23.75087	25.15840	23.79905	26.46925	24.30604	25.28573	22.45112	26.79390	24.55815	23.44214	21.35379	25.36735	24.04016	25.47411	24.05821	1.962357	0.0228027	0.0463906
GO:0033786	heptose-1-phosphate adenylyltransferase activity	molecular_function	22.25496	20.29227	18.66990	NA	NA	NA	22.32166	18.33597	21.15412	NA	23.12155	21.71463	20.24316	NA	21.77679	18.22265	22.68357	19.94328	22.97590	15.74660	22.81087	19.54822	22.45609	21.55460	1.962690	0.0093377	0.0228648
GO:0017169	CDP-alcohol phosphatidyltransferase activity	molecular_function	20.82722	18.86206	19.73467	18.14339	NA	18.30980	21.77806	17.43666	19.04560	NA	21.93411	17.51963	19.18417	18.92687	18.61093	19.38699	20.52258	18.68807	21.56493	18.69993	20.84172	19.94639	21.00455	19.50212	1.965168	0.0012683	0.0043746
GO:0008253	5’-nucleotidase activity	molecular_function	23.77646	21.80827	22.10437	20.89028	18.28988	NA	24.47600	19.95203	21.77783	21.72504	25.28729	22.79413	23.78110	18.21606	NA	15.92113	22.30908	22.54282	24.20162	19.59055	23.09211	19.38430	24.46361	23.84568	1.968197	0.0210086	0.0436890
GO:0008551	cadmium-exporting ATPase activity	molecular_function	22.07819	20.06378	19.83048	18.50254	20.31455	NA	21.01829	20.93400	24.25423	19.92594	20.96385	20.25455	21.73947	20.10822	23.28540	17.37521	20.02665	18.96401	19.26999	18.44524	21.54632	21.25307	21.85884	20.67157	2.014404	0.0141272	0.0316292
GO:0005534	galactose binding	molecular_function	24.05714	22.04147	23.06073	22.27390	24.45775	20.69651	23.63801	21.94256	24.27058	21.87455	24.14626	22.72565	24.39568	22.98265	23.61263	21.85951	24.86752	21.72912	22.80059	21.48000	24.31944	20.46756	23.79993	22.50594	2.015667	0.0000011	0.0000543
GO:0008081	phosphoric diester hydrolase activity	molecular_function	26.94822	24.92378	25.22296	24.41042	23.71286	23.54094	26.67776	23.95242	26.25854	24.61196	27.42143	25.21908	27.31227	23.85884	26.71420	23.01589	26.97924	24.89004	27.96110	23.96782	27.47885	25.12031	27.12782	26.92029	2.024437	0.0002772	0.0014062
GO:0008995	ribonuclease E activity	molecular_function	22.10442	20.07962	19.06004	17.28487	14.44156	20.41160	21.67006	19.30185	21.07710	18.38452	23.11951	19.53166	21.15920	15.52714	21.19856	16.02810	22.68961	19.79778	23.21119	17.05744	22.49896	19.77311	22.78317	22.70346	2.024808	0.0223683	0.0459152
GO:0098656	anion transmembrane transport	biological_process	24.61427	22.58674	23.57557	22.38904	21.77763	22.98408	23.20159	22.21218	25.86438	21.36741	24.17577	22.38202	24.66323	22.37214	25.01020	21.06504	24.99787	24.10082	22.14648	22.31094	24.67317	23.02162	25.61699	21.58232	2.027523	0.0011501	0.0040283
GO:0045254	pyruvate dehydrogenase complex	cellular_component	25.77597	23.73805	22.53462	20.85827	25.06808	25.53179	25.53162	21.70723	23.15637	21.57587	26.45144	23.17056	25.97495	21.39685	24.47897	22.64586	26.32544	23.19327	26.23744	22.84126	26.49378	25.13547	26.48786	24.52949	2.037918	0.0012242	0.0042442
GO:0071949	FAD binding	molecular_function	22.49001	20.43895	24.28299	18.21893	22.34287	18.58691	22.49799	21.97750	21.11382	20.78221	23.08201	20.80712	21.53095	19.91706	21.54365	18.57959	22.01559	21.39588	21.88229	19.76088	22.19849	17.74058	21.51058	20.87370	2.051062	0.0001847	0.0010504
GO:0009375	ferredoxin hydrogenase complex	cellular_component	22.39980	20.33736	18.29589	NA	NA	NA	20.36895	20.37159	21.25910	21.76619	23.65423	18.10365	21.10436	19.59508	21.05212	20.00164	22.73733	19.64042	23.79357	18.36146	22.80322	20.16941	22.15451	21.27824	2.062441	0.0159165	0.0348037
GO:0016408	C-acyltransferase activity	molecular_function	29.66053	27.59512	28.83878	25.26994	29.19175	28.22076	29.68787	27.15765	29.95851	27.70543	29.84535	25.83111	30.33712	27.83994	29.19225	27.31233	30.08400	28.55297	29.16742	27.74979	29.27975	27.49406	29.90611	27.79725	2.065403	0.0000013	0.0000586
GO:0010494	cytoplasmic stress granule	cellular_component	20.96187	18.88002	19.75783	NA	NA	15.44718	19.84473	15.86550	20.52233	16.07417	NA	NA	19.09323	14.42959	20.47426	21.21374	23.27729	19.85115	18.93719	NA	19.52112	17.01210	20.61973	17.23388	2.081852	0.0034518	0.0101093
GO:0042887	amide transmembrane transporter activity	molecular_function	25.30793	23.22273	23.13695	21.59354	21.55045	22.82842	24.98204	22.07806	26.60756	23.39602	25.59369	22.69858	25.80002	22.97786	25.02238	23.04096	24.63916	24.45705	24.39219	22.16118	25.58530	23.47112	26.01053	24.14523	2.085192	0.0014590	0.0049324
GO:0051336	regulation of hydrolase activity	biological_process	22.84862	20.73667	NA	NA	NA	16.05976	21.37090	18.19118	24.16023	22.67433	23.84000	21.62081	23.76805	NA	19.54242	18.19800	23.27116	21.67295	20.39448	15.34216	21.73053	19.85966	20.48850	19.61383	2.111953	0.0142829	0.0318988
GO:0005337	nucleoside transmembrane transporter activity	molecular_function	21.39335	19.27654	NA	NA	19.20415	18.04128	NA	NA	NA	NA	20.36862	NA	NA	NA	20.61171	NA	23.18144	20.26935	21.06772	14.18643	21.14567	14.30352	20.68906	20.61224	2.116809	0.0232302	0.0471193
GO:0045490	pectin catabolic process	biological_process	23.48657	21.35950	24.14065	20.52244	23.38804	21.03309	19.99725	NA	21.26878	18.54933	NA	NA	23.89003	23.15266	19.24380	NA	23.86400	21.96874	24.18912	17.93534	24.50748	20.79386	23.26445	20.92532	2.127074	0.0226257	0.0462381
GO:0008838	diaminopropionate ammonia-lyase activity	molecular_function	24.32970	22.18981	24.55245	14.97396	NA	NA	23.38676	21.28108	24.33995	23.76927	24.45716	21.83703	23.34366	20.58708	23.79347	20.95671	25.15922	23.15124	24.88198	22.64168	24.66325	19.90263	23.37338	22.68999	2.139892	0.0016667	0.0055010
GO:0004850	uridine phosphorylase activity	molecular_function	23.86978	21.72664	20.43686	15.36097	20.96244	20.08065	23.41182	18.33434	21.50016	18.96016	23.96972	17.99528	21.41204	24.66820	22.52947	16.24043	25.65261	22.41222	25.70009	18.76801	23.09337	19.37548	23.18692	21.23883	2.143140	0.0016613	0.0054931
GO:0007346	regulation of mitotic cell cycle	biological_process	24.01031	21.85733	23.57749	20.30730	NA	NA	19.31647	22.04320	23.59748	22.61225	23.94075	22.99873	22.94049	19.46343	23.15597	17.82772	23.75249	22.81674	22.83167	17.47697	26.30775	22.21885	22.23930	21.99314	2.152975	0.0196054	0.0413723
GO:0008679	2-hydroxy-3-oxopropionate reductase activity	molecular_function	20.49891	18.34364	20.14379	15.96189	20.36571	19.25973	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	21.89369	18.67275	20.46528	17.83328	18.63606	17.95100	19.26446	18.60799	2.155274	0.0098185	0.0238062
GO:0004149	dihydrolipoyllysine-residue succinyltransferase activity	molecular_function	23.29703	21.12807	21.04271	20.17639	22.65856	22.51677	22.95987	21.05842	21.67484	20.49575	23.42823	21.40016	21.82439	20.76566	22.02077	18.24294	23.85517	20.95236	25.10649	19.35265	23.19123	21.35713	23.62635	21.97308	2.168956	0.0004626	0.0020119
GO:0004369	glycerol-3-phosphate oxidase activity	molecular_function	22.77558	20.60364	23.36003	22.56328	21.69197	18.43497	21.15364	21.15329	24.37092	18.71764	22.97080	20.43958	24.27814	19.56249	21.02210	21.12325	21.43078	20.86482	19.67529	17.28521	21.64496	16.06021	21.59161	NA	2.171941	0.0039013	0.0111151
GO:0020037	heme binding	molecular_function	25.73952	23.55301	23.86969	22.35842	22.06296	24.20862	25.46403	22.99520	25.14355	23.69901	26.57002	24.06618	25.97515	22.16139	25.35522	21.91674	24.78877	23.21200	25.96497	22.20667	26.00548	22.36003	27.08978	25.34037	2.186503	0.0005775	0.0023673
GO:0050790	regulation of catalytic activity	biological_process	23.38628	21.19422	NA	NA	NA	17.05976	21.98752	18.62987	24.72267	23.12775	24.43928	22.20577	24.08704	NA	19.54242	18.49239	24.12220	22.07547	20.39448	15.34216	22.06557	20.18158	20.48850	19.97455	2.192061	0.0215442	0.0445980
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	molecular_function	25.79654	23.59411	25.20922	22.12790	22.64595	22.47734	25.63536	23.56716	23.75257	22.84300	26.38640	22.64700	25.54367	22.27878	25.53059	22.59812	26.09362	24.65262	26.56651	22.79739	26.22009	22.97816	26.50490	25.54589	2.202427	0.0001216	0.0007844
GO:0005509	calcium ion binding	molecular_function	25.22191	23.01859	27.31557	22.12408	21.08181	23.07085	23.92446	22.48702	23.12952	20.67013	24.17147	22.29477	25.57690	23.81924	23.61720	22.31082	26.59668	23.51686	23.96303	24.17726	23.04569	22.93841	24.72921	22.99888	2.203321	0.0193162	0.0409209
GO:0004397	histidine ammonia-lyase activity	molecular_function	26.82788	24.62015	25.84882	24.81747	25.88968	23.60497	26.51932	24.66163	27.43585	23.86899	26.87579	23.82201	27.44007	22.80232	26.14185	21.38092	26.64557	26.52867	25.30874	25.49214	27.76731	18.14680	27.21458	24.85287	2.207730	0.0004968	0.0021298
GO:0007088	regulation of mitotic nuclear division	biological_process	23.15880	20.94699	22.57749	19.30730	NA	NA	NA	21.04320	22.44273	21.61225	22.91971	21.98264	21.57195	16.96430	22.01506	16.82772	22.60824	21.75224	NA	NA	25.22767	21.04931	20.91969	20.99314	2.211809	0.0119630	0.0278005
GO:0009001	serine O-acetyltransferase activity	molecular_function	19.51834	17.30628	NA	15.70844	NA	NA	18.62603	NA	18.12469	NA	20.20993	18.39054	NA	NA	17.90464	16.60312	18.53310	15.05364	20.11945	18.38352	19.91404	NA	20.36733	16.60560	2.212064	0.0024350	0.0075466
GO:1904680	peptide transmembrane transporter activity	molecular_function	25.03063	22.81661	22.20452	20.92570	20.94996	22.77904	24.58234	20.61096	26.27953	23.09530	25.34772	22.05005	25.60608	22.72807	24.70645	22.49052	24.38283	23.95631	24.25062	21.05659	25.36396	22.96792	25.77490	24.07426	2.214015	0.0024438	0.0075653
GO:0008686	3,4-dihydroxy-2-butanone-4-phosphate synthase activity	molecular_function	20.71678	18.50193	NA	NA	NA	NA	20.82694	NA	21.42211	NA	21.08055	17.39440	20.40973	NA	20.84876	16.40535	20.18601	19.10832	19.79918	17.64429	19.37156	NA	21.28633	19.65754	2.214850	0.0004426	0.0019497
GO:0042645	mitochondrial nucleoid	cellular_component	21.18375	18.94503	17.65368	NA	18.84352	20.57433	19.61515	18.47784	21.30411	19.49095	19.17264	17.98840	22.44368	19.04929	NA	18.57350	22.53735	18.83114	20.17887	15.87178	22.34700	17.63167	19.69164	18.81622	2.238725	0.0122823	0.0284598
GO:0004849	uridine kinase activity	molecular_function	23.81251	21.56572	23.17481	21.14286	22.48953	21.73217	24.94784	20.22746	22.24559	20.10594	24.03976	21.38523	21.00719	21.50845	24.25491	20.04352	20.83315	21.50087	23.77377	20.95279	24.66340	22.47946	24.69763	22.99184	2.246794	0.0010483	0.0037270
GO:0009256	10-formyltetrahydrofolate metabolic process	biological_process	25.95487	23.70066	22.98917	22.81726	25.59272	24.86928	25.79930	23.16048	26.67186	22.73736	25.58644	23.06378	26.37471	23.04584	25.96161	22.97857	26.22280	25.12180	24.38330	23.89929	26.72683	22.88998	26.20248	23.24506	2.254206	0.0000281	0.0003940
GO:0009257	10-formyltetrahydrofolate biosynthetic process	biological_process	25.94976	23.69273	22.98917	22.81726	25.51885	24.83007	25.79930	23.16048	26.67186	22.73736	25.58644	23.06378	26.37471	23.04584	25.96161	22.97857	26.22280	25.12180	24.38330	23.89929	26.72683	22.88998	26.20248	23.24506	2.257030	0.0000278	0.0003938
GO:0008340	determination of adult lifespan	biological_process	22.84293	20.57941	NA	NA	NA	NA	21.84912	19.38942	23.48426	19.76449	23.50490	NA	21.80943	17.05748	22.37305	NA	23.89820	20.55249	20.92168	NA	22.81504	19.66792	22.56066	22.34198	2.263522	0.0013787	0.0047078
GO:0008777	acetylornithine deacetylase activity	molecular_function	26.08994	23.80082	26.03595	19.38045	NA	NA	23.97307	23.01966	25.97676	25.30412	26.58788	24.04815	25.66842	21.83906	24.35965	22.60678	26.22893	24.29707	26.78572	23.88110	27.32983	22.18784	24.52811	24.69689	2.289124	0.0007852	0.0029599
GO:0006108	malate metabolic process	biological_process	26.70127	24.41122	24.06907	21.14545	21.68763	NA	26.86944	21.94031	25.79582	23.39567	27.01017	21.67938	25.68290	21.65553	26.06398	20.26732	27.41038	24.04844	28.16128	21.02650	27.22188	21.85498	26.63403	27.37884	2.290051	0.0003991	0.0018048
GO:0009570	chloroplast stroma	cellular_component	25.15921	22.85690	22.93831	21.65382	22.35340	22.23074	25.35380	22.70983	24.20821	22.52909	25.58628	22.74326	23.66348	22.79628	25.20957	22.16554	25.88786	23.99796	26.24221	22.22044	25.74710	22.34187	25.11171	23.97262	2.302312	0.0001394	0.0008585
GO:0015430	glycerol-3-phosphate-transporting ATPase activity	molecular_function	22.68609	20.37532	24.54096	16.29471	23.34332	18.47146	21.58993	18.01331	20.07642	19.79176	20.93311	18.95762	21.72977	20.48904	21.31198	20.51536	22.66160	20.38468	23.38833	20.84438	22.14385	22.24273	22.12848	20.65519	2.310773	0.0007732	0.0029270
GO:0044461	bacterial-type flagellum part	cellular_component	23.73306	21.41411	22.89323	18.60562	20.63543	20.47569	22.74259	19.29455	25.09526	19.99779	24.44555	18.36329	23.70771	18.24928	22.14734	22.69238	25.57804	23.43492	20.22364	19.78005	21.32834	22.61220	22.50509	20.08631	2.318953	0.0034871	0.0101805
GO:0003941	L-serine ammonia-lyase activity	molecular_function	24.08353	21.76151	21.17985	18.87426	23.70677	22.66011	22.46382	20.73699	22.64257	21.20464	23.85605	22.81712	22.22021	21.34243	21.81479	16.20845	26.68170	23.01288	22.76553	21.32436	23.66037	21.12624	23.87252	22.04640	2.322021	0.0092107	0.0226150
GO:0008934	inositol monophosphate 1-phosphatase activity	molecular_function	21.85940	19.50273	20.80791	19.09335	NA	NA	21.60414	17.17349	19.85321	14.85906	22.67871	20.12713	NA	18.99757	20.28778	19.05494	21.68555	19.76373	23.13314	17.61243	22.01762	16.75201	21.72257	21.64419	2.356671	0.0006841	0.0026890
GO:0052832	inositol monophosphate 3-phosphatase activity	molecular_function	21.85940	19.50273	20.80791	19.09335	NA	NA	21.60414	17.17349	19.85321	14.85906	22.67871	20.12713	NA	18.99757	20.28778	19.05494	21.68555	19.76373	23.13314	17.61243	22.01762	16.75201	21.72257	21.64419	2.356671	0.0006841	0.0026890
GO:0102391	decanoate-CoA ligase activity	molecular_function	21.48736	19.13041	NA	NA	NA	NA	21.09089	19.15355	22.87214	19.65976	21.99020	18.04487	21.37102	20.02749	19.92796	20.08904	18.06467	18.15721	19.74088	17.58730	20.69677	14.86136	22.47340	19.57317	2.356945	0.0064685	0.0169378
GO:0008675	2-dehydro-3-deoxy-phosphogluconate aldolase activity	molecular_function	22.90972	20.55234	23.90318	19.94409	24.57562	20.15952	19.52816	20.58076	20.17302	18.00950	19.73524	18.50350	21.79800	21.62182	19.89693	21.29066	23.65223	21.27882	23.05536	19.50164	23.05163	19.75470	22.92395	21.29190	2.357386	0.0119108	0.0277793
GO:0009102	biotin biosynthetic process	biological_process	22.93046	20.57227	NA	NA	22.28802	21.37300	22.87969	17.32725	23.78948	19.28492	22.71493	18.71783	22.71566	18.47851	22.78413	15.72064	22.16404	20.10870	22.03086	20.71459	23.20370	19.33876	23.62761	22.87772	2.358195	0.0000736	0.0006062
GO:0090224	regulation of spindle organization	biological_process	22.93787	20.57308	22.56799	NA	NA	NA	NA	NA	22.43008	21.49777	22.91286	20.20085	21.57195	16.96430	22.01506	16.82772	22.56423	21.64480	NA	NA	24.78833	NA	20.91824	20.67157	2.364796	0.0080597	0.0203023
GO:0015496	putrescine:ornithine antiporter activity	molecular_function	21.76563	19.39748	NA	NA	NA	NA	NA	NA	22.02878	19.29929	22.94363	19.26783	NA	NA	21.27488	19.57153	22.21217	16.49127	21.12107	NA	20.62028	NA	20.33544	20.31596	2.368149	0.0043169	0.0121338
GO:0008700	4-hydroxy-2-oxoglutarate aldolase activity	molecular_function	22.92985	20.55599	23.90318	19.94409	24.57562	20.06152	19.56271	20.72582	20.17302	18.00950	19.73524	18.50350	21.79800	21.62182	19.89693	21.24770	23.77786	21.29527	23.05536	19.50164	23.05163	19.75470	22.92395	21.29190	2.373860	0.0116694	0.0273663
GO:0030497	fatty acid elongation	biological_process	24.02557	21.64647	21.21925	NA	21.22155	21.16784	24.35647	22.05682	23.90970	22.40665	25.38375	20.70791	23.61904	20.03804	23.85264	21.77416	23.75566	21.63855	24.53960	16.91712	23.84948	20.91636	24.27125	23.06994	2.379103	0.0009283	0.0034049
GO:0008137	NADH dehydrogenase (ubiquinone) activity	molecular_function	24.82376	22.43911	21.79439	NA	NA	NA	23.96080	18.40246	22.15403	19.63199	25.71779	18.02399	25.31065	20.27881	24.91365	NA	25.22558	23.50102	24.80357	20.28267	24.13153	20.41415	25.76508	24.75174	2.384649	0.0006894	0.0027010
GO:0015179	L-amino acid transmembrane transporter activity	molecular_function	21.78274	19.39748	NA	NA	NA	NA	NA	NA	22.02878	19.29929	22.94363	19.26783	NA	NA	21.27488	19.57153	22.29801	16.49127	21.12107	NA	20.62028	NA	20.33544	20.31596	2.385266	0.0043110	0.0121297
GO:0031132	serine 3-dehydrogenase activity	molecular_function	22.22805	19.84170	NA	NA	NA	19.25416	22.38431	NA	22.33694	18.23873	22.19581	NA	23.20678	21.36677	21.50133	20.71020	20.26887	19.71476	18.50623	19.95478	19.94339	17.93086	23.66959	15.13535	2.386349	0.0118127	0.0276784
GO:0009092	homoserine metabolic process	biological_process	21.94432	19.55716	NA	NA	NA	17.33035	22.38238	20.43276	23.85535	19.14449	21.58912	20.99398	22.24554	18.63456	19.62438	19.26417	19.73134	17.74922	18.22048	18.50829	21.18260	20.46778	21.60247	18.55877	2.387160	0.0072568	0.0186560
GO:0008911	lactaldehyde dehydrogenase activity	molecular_function	23.80364	21.39682	23.10632	NA	NA	NA	23.63865	20.69667	24.71920	22.26461	24.16223	22.61986	24.17393	18.54218	23.30750	17.68471	23.04153	22.68356	19.58348	18.22805	23.15002	19.52866	24.83384	21.64269	2.406825	0.0018634	0.0059667
GO:0015645	fatty acid ligase activity	molecular_function	21.74601	19.31160	NA	NA	NA	NA	21.49728	19.15355	22.87214	19.65976	22.38433	18.04487	21.37102	20.02749	20.17238	20.08904	18.06467	18.15721	20.62262	17.64967	21.12073	14.86136	22.83471	20.47999	2.434415	0.0046172	0.0128319
GO:0022904	respiratory electron transport chain	biological_process	24.37754	21.94076	19.55728	NA	21.95769	21.75038	24.49833	20.18076	22.46032	21.17269	25.45994	19.92237	25.40213	22.64863	23.59730	18.42990	24.41472	20.99639	24.61866	21.55141	24.34452	21.92303	24.96830	23.94158	2.436786	0.0027537	0.0083162
GO:0043647	inositol phosphate metabolic process	biological_process	21.86281	19.39984	19.51324	NA	NA	NA	21.66991	18.69850	19.85321	14.85906	22.69815	19.20748	NA	NA	20.52278	19.30468	21.92233	19.06078	23.13314	17.61243	21.95386	16.75201	21.83644	21.50112	2.462969	0.0014283	0.0048405
GO:0010038	response to metal ion	biological_process	27.30929	24.84577	26.34980	22.14304	25.29815	23.92193	27.35611	24.38195	26.99593	25.38687	27.24831	23.23492	27.41203	23.91551	27.16960	24.57589	27.99375	25.65279	27.87078	26.15726	27.62200	24.19911	27.49177	25.51233	2.463513	0.0000030	0.0000906
GO:0050242	pyruvate, phosphate dikinase activity	molecular_function	25.14815	22.67448	20.34288	23.03184	24.29790	17.83487	26.05827	22.76243	25.68889	22.35905	24.51582	22.99359	25.68389	20.95961	25.84076	20.09158	23.26105	23.41802	22.51140	22.76332	24.43827	20.47654	26.36358	24.32648	2.473668	0.0042297	0.0119717
GO:0004801	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity	molecular_function	24.87722	22.38659	23.18913	18.10157	22.40801	22.67382	25.02581	22.40182	23.77153	22.21073	25.63264	21.07384	23.21637	21.74622	24.18808	21.03213	26.02970	23.80297	25.47876	18.88740	25.05957	22.49820	25.39959	23.74236	2.490635	0.0003140	0.0015320
GO:0004730	pseudouridylate synthase activity	molecular_function	22.06089	19.56760	21.76148	15.89113	22.06996	18.24297	20.86894	20.19571	NA	NA	NA	NA	22.59813	17.72705	NA	NA	23.66231	21.08004	20.07138	17.70803	21.62834	20.70347	20.14512	18.14010	2.493297	0.0020332	0.0064109
GO:0102420	sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	molecular_function	22.19157	19.69153	19.16592	NA	NA	NA	22.09921	16.45858	19.19945	17.82954	23.50635	19.84246	18.52942	13.20297	19.60869	NA	21.29337	17.95377	23.22354	15.51837	22.70100	19.18471	23.24478	22.13463	2.500043	0.0062186	0.0164419
GO:0051235	maintenance of location	biological_process	26.48880	23.98537	25.31929	23.35980	NA	NA	27.90705	24.25823	26.09706	23.79193	25.66467	23.72446	26.41896	22.44768	25.49802	NA	25.14656	24.93939	21.95719	NA	27.80179	NA	26.72471	24.19056	2.503438	0.0094362	0.0230852
GO:0009658	chloroplast organization	biological_process	24.14858	21.64356	21.78209	NA	NA	NA	23.18689	21.27114	21.88195	22.95786	24.84264	21.50096	25.67434	21.90525	22.91596	21.10672	20.70595	19.68366	25.33453	20.03825	24.52262	20.41059	23.14550	22.59628	2.505012	0.0048215	0.0132910
GO:0042493	response to drug	biological_process	24.24785	21.72459	19.81790	20.52101	20.22109	23.57758	23.28549	20.37427	21.76259	20.44968	23.92289	21.80265	21.12374	18.71391	22.07651	19.15509	27.13310	23.72555	23.50645	19.12746	23.92247	19.59900	22.41559	20.41217	2.523258	0.0230451	0.0468136
GO:0016841	ammonia-lyase activity	molecular_function	28.74580	26.22212	27.33669	25.48606	26.52135	24.80308	28.52536	26.03265	28.84335	26.53175	28.87734	25.54932	28.74539	25.30198	27.98249	25.04146	29.92034	27.87763	28.40834	26.24387	29.25656	24.38142	29.15012	27.12338	2.523686	0.0000040	0.0001121
GO:0015980	energy derivation by oxidation of organic compounds	biological_process	29.45790	26.92074	27.62892	26.01427	27.87597	26.61180	29.52385	26.59811	29.95868	26.54811	29.63985	26.16737	29.97707	27.45802	29.42554	26.34288	28.98437	28.14989	29.45065	27.06679	29.88239	26.67954	29.85852	27.02643	2.537160	0.0000001	0.0000098
GO:0031522	cell envelope Sec protein transport complex	cellular_component	22.06478	19.52608	NA	NA	18.94348	20.39910	21.80482	NA	22.94394	NA	21.90996	NA	21.80245	18.21376	20.32668	NA	23.24041	21.10632	21.34265	15.38817	22.37492	17.57643	22.16775	18.40570	2.538700	0.0017089	0.0056035
GO:0015949	nucleobase-containing small molecule interconversion	biological_process	22.89390	20.35004	19.54277	NA	22.06826	21.56854	23.17476	18.50072	NA	21.09965	22.93181	15.31271	20.35631	17.07295	23.61973	19.95145	23.84717	19.63274	23.65658	20.45406	22.86775	19.89068	22.28393	21.62004	2.543856	0.0015821	0.0053155
GO:0046459	short-chain fatty acid metabolic process	biological_process	24.43713	21.86882	NA	NA	22.46261	22.49686	23.36115	21.95870	21.53547	21.55077	23.41747	18.90978	23.89309	21.25986	23.23025	21.29559	26.99478	22.98956	23.53117	20.81299	23.84164	21.30239	23.25968	22.71751	2.568308	0.0024561	0.0075859
GO:0006072	glycerol-3-phosphate metabolic process	biological_process	26.29181	23.71976	24.38137	23.81535	22.83884	22.89333	25.99315	23.49583	26.51072	22.22888	26.69923	24.13875	26.00182	23.46016	24.12127	23.09158	28.10815	24.91711	27.25517	22.86052	24.79604	23.78744	25.21223	24.24964	2.572048	0.0006163	0.0024852
GO:0033585	L-phenylalanine biosynthetic process from chorismate via phenylpyruvate	biological_process	22.12683	19.55218	NA	NA	NA	NA	22.21558	18.02537	20.72157	16.82372	22.43989	16.97830	20.02988	NA	21.75904	NA	22.97452	20.58291	22.66272	15.56917	21.83307	18.48621	22.44029	21.45914	2.574643	0.0004034	0.0018151
GO:0009068	aspartate family amino acid catabolic process	biological_process	29.54288	26.96760	27.58052	24.64818	28.35966	27.68975	29.65545	26.41772	30.05720	26.68633	29.27851	25.11250	30.10998	26.87970	29.32055	26.40805	30.19547	28.43828	28.92201	27.00269	29.87134	26.38813	29.73739	27.32700	2.575281	0.0000014	0.0000594
GO:0004366	glycerol-3-phosphate O-acyltransferase activity	molecular_function	22.19157	19.61613	19.16592	NA	NA	NA	22.09921	16.45858	19.19945	17.82954	23.50635	18.62115	18.52942	13.20297	19.60869	NA	21.29337	17.95377	23.22354	15.51837	22.70100	19.58762	23.24478	22.13463	2.575439	0.0046640	0.0129353
GO:0000041	transition metal ion transport	biological_process	27.09174	24.50710	25.37659	21.45173	23.45545	23.10510	28.05915	25.03417	26.53770	23.21941	27.29357	23.71886	25.58074	24.86376	26.70096	24.64876	25.19117	22.39721	27.62026	24.05422	28.11187	25.12832	28.07467	26.17957	2.584642	0.0004582	0.0020055
GO:0008859	exoribonuclease II activity	molecular_function	24.18309	21.59618	22.55372	21.45048	18.79371	20.20267	24.22419	20.37609	24.17137	21.60556	24.90700	21.30693	23.10724	21.50692	23.09920	21.29878	24.57129	21.68914	25.00401	18.26741	24.92140	22.92982	24.55136	22.61132	2.586916	0.0015938	0.0053393
GO:0009443	pyridoxal 5’-phosphate salvage	biological_process	22.59340	20.00483	NA	NA	NA	NA	22.61194	18.41412	20.92261	18.86051	22.46582	18.14013	20.42247	17.33828	21.60992	15.26328	19.06573	18.68187	22.75663	17.30046	22.39387	15.96374	24.57615	22.83918	2.588573	0.0006378	0.0025533
GO:0005951	carbamoyl-phosphate synthase complex	cellular_component	22.69194	20.08345	NA	NA	NA	NA	23.49595	20.54549	21.30534	18.42639	22.09498	20.65161	21.97811	20.43335	23.46323	20.38045	20.93262	20.29915	NA	NA	20.56530	20.11763	23.93656	17.18890	2.608489	0.0016272	0.0054001
GO:0070482	response to oxygen levels	biological_process	25.31585	22.70317	24.91421	21.24284	23.87981	21.93280	25.87260	22.45088	23.79286	22.30724	25.04128	20.00903	NA	NA	25.13999	22.74109	24.59327	22.56486	NA	NA	26.55011	22.68227	25.78467	24.45824	2.612680	0.0000431	0.0004726
GO:0036293	response to decreased oxygen levels	biological_process	25.25215	22.63617	24.85766	21.20440	23.85362	21.74430	25.80839	22.37464	23.75688	22.18924	25.00805	19.78065	NA	NA	25.13399	22.71712	24.54449	22.37827	NA	NA	26.42897	22.61594	25.73346	24.44533	2.615978	0.0000427	0.0004726
GO:0033926	glycopeptide alpha-N-acetylgalactosaminidase activity	molecular_function	25.54507	22.92039	26.18068	22.94178	25.56867	20.59590	24.08684	22.15150	22.16638	22.97398	23.47896	22.36011	24.54114	23.51552	23.65752	21.74757	26.93234	23.98821	25.70164	22.61548	26.24007	22.65129	26.23459	23.76261	2.624674	0.0003270	0.0015785
GO:0004049	anthranilate synthase activity	molecular_function	23.03643	20.40555	17.62271	NA	NA	17.70106	22.88845	16.92135	24.27796	19.31981	23.28054	17.69340	23.32425	20.29490	22.63012	21.09199	21.47735	21.30865	NA	21.52456	22.69135	21.35056	23.54556	19.74057	2.630882	0.0049811	0.0136891
GO:0005839	proteasome core complex	cellular_component	21.37950	18.74360	19.06254	NA	18.44461	17.81805	18.25602	14.80453	NA	17.29768	21.58561	15.98333	NA	NA	21.55957	14.33343	23.14299	20.54749	21.85264	NA	20.64070	18.52929	21.20283	20.06151	2.635904	0.0045948	0.0127827
GO:0061621	canonical glycolysis	biological_process	23.19773	20.55676	18.29959	NA	NA	NA	20.44557	NA	21.75085	19.51995	22.01778	16.65412	20.63432	NA	21.90562	NA	25.84121	22.72296	23.75429	18.34901	22.17291	15.84346	21.02465	20.04788	2.640968	0.0216096	0.0446994
GO:0004029	aldehyde dehydrogenase (NAD) activity	molecular_function	25.45764	22.81459	23.99642	22.03984	24.71908	22.88768	25.86842	21.72851	25.88065	23.17894	25.79808	23.73730	24.92048	19.28435	24.94379	18.70209	25.48259	24.45797	23.09144	20.78368	25.34859	20.98010	26.82115	23.75275	2.643047	0.0000686	0.0005850
GO:0004359	glutaminase activity	molecular_function	23.31934	20.66886	NA	NA	18.30728	17.97677	23.57697	21.18174	23.64295	19.89552	23.58722	18.60245	23.62720	21.50339	23.58489	20.31257	21.54390	21.45337	NA	NA	23.07802	21.71604	24.11842	18.61644	2.650488	0.0036094	0.0104810
GO:0030030	cell projection organization	biological_process	25.10960	22.45726	22.56682	NA	21.58625	22.79563	24.69511	21.92642	24.17262	21.42281	26.21934	19.13474	24.24815	20.56925	24.55456	21.79001	26.09674	23.48202	26.06496	23.65667	25.35643	23.39638	25.06835	20.75369	2.652342	0.0004580	0.0020055
GO:0009244	lipopolysaccharide core region biosynthetic process	biological_process	23.09281	20.43265	19.23117	NA	NA	NA	23.02384	18.29299	22.28103	20.08150	23.63164	21.34699	20.54632	NA	22.72892	18.83954	24.26862	21.24845	23.55662	18.90834	23.21935	16.74707	23.44569	21.80409	2.660161	0.0017337	0.0056568
GO:0006869	lipid transport	biological_process	22.20590	19.54475	18.20875	17.78903	17.52711	18.77370	22.27133	18.60420	19.19995	15.62762	22.91485	19.31456	19.72296	18.78288	21.83810	18.50740	23.27678	19.46060	22.96116	20.85181	23.05056	19.77565	22.84235	21.13448	2.661147	0.0089536	0.0221437
GO:0016833	oxo-acid-lyase activity	molecular_function	26.75567	24.08363	25.49191	22.87843	26.90606	23.06695	26.52647	23.83040	27.25817	23.92080	26.99625	23.72252	26.82947	24.64128	27.15631	24.14040	26.09204	25.00595	25.23705	23.85919	26.45313	24.03333	27.65001	24.49764	2.672041	0.0000000	0.0000033
GO:0018298	protein-chromophore linkage	biological_process	24.93312	22.23016	NA	NA	NA	NA	25.37967	NA	25.21014	20.76315	24.43296	NA	25.35542	21.27425	24.80984	19.55192	23.13177	24.05284	20.47883	NA	25.69178	21.43924	25.45511	21.99765	2.702967	0.0042919	0.0121010
GO:0047061	glucose-fructose oxidoreductase activity	molecular_function	21.57970	18.86844	NA	NA	22.78431	19.54089	22.06761	18.03800	17.88410	17.74329	21.05955	15.96534	NA	20.50425	19.88098	NA	18.48248	16.35665	23.15296	19.50604	20.33747	NA	21.05473	17.59280	2.711261	0.0071091	0.0183850
GO:0004309	exopolyphosphatase activity	molecular_function	24.24026	21.52154	21.53325	20.64047	18.68429	19.76888	23.80707	21.02987	25.67345	20.52649	24.30700	21.93455	24.74484	21.76983	24.00710	20.89403	23.73831	22.71741	22.94325	20.33159	24.99986	22.53309	24.57548	21.57202	2.718715	0.0021318	0.0066754
GO:0019541	propionate metabolic process	biological_process	24.32193	21.58048	NA	NA	20.16583	20.13941	23.36115	21.95870	21.49898	21.55077	23.41059	18.16542	23.59218	21.07752	23.15791	21.28671	26.89814	22.71092	23.47095	20.68370	23.82958	21.27920	23.25968	22.71751	2.741456	0.0065536	0.0170947
GO:0006553	lysine metabolic process	biological_process	29.83399	27.06515	25.35896	25.45864	25.73425	25.99897	30.27437	26.54417	30.85560	26.68053	29.71270	26.78127	30.75457	27.24311	29.99401	27.12642	28.50737	28.75520	27.60718	26.04869	30.38814	27.18114	30.41833	26.96108	2.768832	0.0025229	0.0077483
GO:0017016	Ras GTPase binding	molecular_function	23.81258	21.04221	22.56799	NA	NA	16.64379	NA	NA	23.61561	21.49777	23.32907	20.20085	25.01520	21.22971	24.00592	16.82772	22.86056	22.53081	19.83663	21.32745	24.78833	NA	23.81008	20.73052	2.770375	0.0031451	0.0093424
GO:0008797	aspartate ammonia-lyase activity	molecular_function	27.26102	24.48635	25.00313	15.34108	NA	NA	26.44431	23.91545	26.48006	25.56362	27.25082	21.32296	26.07398	22.85142	25.56576	23.78578	28.98286	25.34835	27.78549	22.97569	27.41627	22.01747	27.33091	26.41876	2.774667	0.0016961	0.0055811
GO:1901264	carbohydrate derivative transport	biological_process	23.83365	21.05391	20.02797	NA	NA	NA	25.51854	17.32657	19.65883	19.70182	23.38907	17.83459	20.89060	23.23852	21.98734	19.82460	25.50299	21.19903	23.50925	19.19799	23.80235	20.48779	22.98979	21.53449	2.779742	0.0083708	0.0209501
GO:0006543	glutamine catabolic process	biological_process	22.89466	20.10623	NA	NA	18.30728	17.97677	23.43724	19.41586	23.20057	NA	22.85243	NA	23.12847	21.34371	23.34180	18.51911	21.30022	20.76321	NA	NA	22.54135	20.92987	23.60947	16.97841	2.788435	0.0032537	0.0096441
GO:0005354	galactose transmembrane transporter activity	molecular_function	23.93764	21.11578	21.29744	17.25126	21.30458	18.16769	24.75876	19.68921	24.59064	19.57053	24.26923	20.33839	24.10495	22.00567	23.95868	19.52653	23.84349	22.42534	24.01843	18.88138	23.86069	22.90863	23.93857	21.33263	2.821856	0.0000360	0.0004308
GO:0015944	formate oxidation	biological_process	23.89870	21.06962	NA	NA	NA	NA	23.10967	NA	21.58616	18.00211	23.27009	NA	21.93524	19.13816	22.58481	NA	25.99177	23.23593	24.28509	16.22293	23.50461	NA	23.11255	17.67436	2.829085	0.0011714	0.0040925
GO:0071310	cellular response to organic substance	biological_process	24.51925	21.68832	NA	NA	20.64157	21.46264	24.76508	20.33727	19.46643	20.93779	23.27059	16.71840	NA	NA	23.99200	NA	26.79573	24.01808	22.19733	19.04629	24.97088	19.67423	22.11429	21.15616	2.830931	0.0227472	0.0463657
GO:1901617	organic hydroxy compound biosynthetic process	biological_process	27.69617	24.84726	21.73487	22.76585	23.96754	23.90098	28.55372	23.86587	28.15415	23.99764	28.09141	24.56468	27.85415	25.32454	28.07739	24.41192	28.31612	26.77955	24.24829	23.44847	27.94386	25.18086	27.92743	24.47688	2.848910	0.0059919	0.0159666
GO:0046405	glycerol dehydratase activity	molecular_function	25.22325	22.37090	22.48391	18.59428	16.45513	19.57550	25.07352	23.45687	27.14448	24.23956	23.46387	20.65290	26.42216	20.90891	24.91430	22.60432	25.57412	23.10737	24.27219	21.34129	24.16645	18.71644	24.18677	22.26666	2.852352	0.0197084	0.0415252
GO:0040011	locomotion	biological_process	25.17703	22.32458	22.37918	22.35822	21.98468	21.28103	25.51547	20.53371	25.19207	20.80150	24.81744	21.14906	23.78976	19.06616	20.71971	22.51391	27.75689	24.44011	22.46379	20.13126	25.10023	23.50540	22.74476	20.80029	2.852450	0.0062428	0.0164897
GO:1901505	carbohydrate derivative transmembrane transporter activity	molecular_function	25.04242	22.18362	24.96055	21.12844	23.52215	21.75559	24.05620	19.60068	23.99340	21.05301	26.07675	21.41393	24.42271	22.08873	24.74019	21.53711	24.79502	22.35792	26.02955	22.46191	25.54515	22.84039	24.99389	23.80299	2.858798	0.0000005	0.0000347
GO:1901701	cellular response to oxygen-containing compound	biological_process	23.55306	20.69123	19.44732	20.51899	19.66496	NA	22.68944	20.29181	19.89155	20.35303	23.18189	19.87202	20.53702	18.12895	21.46129	19.04184	26.48460	23.13451	22.34028	18.04836	23.22150	18.69195	21.60460	20.09075	2.861831	0.0180132	0.0386729
GO:0004121	cystathionine beta-lyase activity	molecular_function	23.39336	20.52945	20.74119	18.56671	NA	NA	23.54319	21.61217	22.61334	20.58166	23.96637	20.86560	21.64852	15.69484	22.60808	18.45725	17.89374	NA	24.02015	16.30866	24.79134	20.52016	24.05450	22.11738	2.863905	0.0054568	0.0147432
GO:0008641	ubiquitin-like modifier activating enzyme activity	molecular_function	20.55670	17.67213	NA	NA	NA	NA	20.99003	NA	NA	NA	20.08878	15.86307	20.48402	NA	21.49714	13.00300	16.68864	19.33924	NA	NA	18.72004	17.84551	21.32919	16.24496	2.884567	0.0137053	0.0309137
GO:0004109	coproporphyrinogen oxidase activity	molecular_function	20.31733	17.42305	NA	NA	NA	NA	NA	NA	21.85032	NA	18.19520	18.00242	NA	18.06708	20.63738	NA	18.58826	14.50820	18.25270	NA	20.85088	17.13472	19.67318	17.41097	2.894279	0.0098009	0.0237847
GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	molecular_function	25.42221	22.51212	24.16735	23.02121	22.69466	20.62847	23.85894	23.69500	25.28706	20.74218	25.70957	21.50843	25.85075	20.69811	24.57047	22.15818	27.29706	23.70733	25.57551	22.33111	25.21964	20.29366	24.14238	23.35210	2.910086	0.0000269	0.0003880
GO:0000398	mRNA splicing, via spliceosome	biological_process	22.59202	19.66615	NA	NA	NA	NA	24.50048	NA	20.60401	19.28198	18.69588	18.83935	NA	19.59647	21.29077	18.93461	21.47585	19.34158	NA	NA	21.79722	NA	23.16067	20.87801	2.925868	0.0211713	0.0439357
GO:0019645	anaerobic electron transport chain	biological_process	22.11926	19.18342	NA	NA	18.92947	18.40355	23.60725	17.52830	20.99649	19.53425	23.21930	19.16476	22.26986	18.08646	19.53129	13.99097	22.33212	17.33037	20.24738	NA	19.60226	18.91383	22.79677	21.26626	2.935847	0.0018887	0.0060251
GO:0046686	response to cadmium ion	biological_process	26.82439	23.88356	25.71783	20.53517	24.39161	23.05775	26.74200	23.70020	26.69476	25.01443	26.72325	22.88134	27.18491	22.32409	26.67417	23.86556	27.71946	25.37051	27.27623	23.72502	26.91466	23.48398	26.93873	23.86030	2.940831	0.0000015	0.0000594
GO:0046855	inositol phosphate dephosphorylation	biological_process	21.79783	18.85070	18.46376	NA	NA	NA	21.66991	15.21931	19.85321	14.85906	22.64715	15.71995	NA	NA	20.45283	17.48805	21.59024	17.59074	23.13314	17.61243	21.95386	16.75201	21.83644	21.50112	2.947133	0.0002125	0.0011482
GO:0008889	glycerophosphodiester phosphodiesterase activity	molecular_function	25.72098	22.77189	22.99337	NA	NA	NA	25.33268	18.31985	25.40441	21.93146	25.74900	19.81101	26.19723	20.22864	25.52799	18.46301	25.67153	20.84983	26.34133	19.84916	26.22804	19.45639	25.82103	25.68821	2.949091	0.0000057	0.0001355
GO:0004082	bisphosphoglycerate mutase activity	molecular_function	22.91021	19.95113	20.73228	NA	NA	NA	22.45036	16.76022	23.06321	18.22586	22.96642	17.78179	22.75368	18.80857	22.62173	17.66066	22.84046	22.15599	NA	NA	23.84154	20.08611	23.31572	NA	2.959080	0.0000463	0.0004873
GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor	molecular_function	24.17969	21.20320	23.36003	22.56328	21.69197	18.43497	22.07573	21.15329	25.76883	19.47180	23.58208	20.43958	26.42515	20.31629	23.49752	21.12507	22.58584	21.74458	19.67529	17.28521	22.63493	22.47849	22.28931	NA	2.976486	0.0040585	0.0115268
GO:0044462	external encapsulating structure part	cellular_component	29.99838	27.01914	28.01459	25.35717	25.54894	26.33545	30.12067	26.22020	29.67314	27.24816	30.37555	26.65974	29.72635	27.16730	29.98532	24.84991	30.10660	28.01634	30.37520	26.87519	30.98222	26.16744	30.42359	28.47824	2.979238	0.0000464	0.0004873
GO:0035690	cellular response to drug	biological_process	23.60196	20.61741	19.44732	20.51899	NA	NA	22.59764	20.26822	19.76230	20.33471	22.81823	17.07480	20.53702	18.12895	21.35174	19.04184	26.44466	23.09744	22.14476	12.61002	23.19328	NA	21.07779	18.76209	2.984554	0.0155595	0.0341605
GO:0009279	cell outer membrane	cellular_component	29.98198	26.99429	28.00582	25.35372	25.54472	26.31564	30.11236	26.15239	29.65635	27.17075	30.35851	26.65843	29.71134	27.15200	29.97366	24.80886	30.04994	27.99401	30.35647	26.86117	30.97514	26.14859	30.41554	28.46463	2.987693	0.0000438	0.0004759
GO:0015440	peptide-transporting ATPase activity	molecular_function	22.74167	19.72535	NA	NA	19.14473	15.90135	22.88831	NA	24.29372	17.56517	22.87976	NA	22.54019	17.92395	22.50526	19.23924	21.92494	22.07157	18.43285	NA	22.76587	17.88682	23.25159	18.17014	3.016324	0.0011665	0.0040804
GO:0009276	Gram-negative-bacterium-type cell wall	cellular_component	23.26627	20.23945	19.43756	NA	NA	NA	23.54491	13.38543	21.35996	19.22142	23.59402	18.96115	21.91036	19.31525	22.65188	18.86915	22.42040	20.51503	24.24854	16.90845	24.46414	21.40801	23.67215	22.09296	3.026819	0.0011334	0.0039852
GO:0015572	N-acetylglucosamine transmembrane transporter activity	molecular_function	22.86444	19.78285	19.04425	NA	18.53454	NA	22.81274	NA	23.15341	NA	23.73408	18.44305	22.46529	19.10269	23.19921	NA	22.71647	19.45988	22.85372	17.57516	22.97048	19.55773	23.77123	21.41949	3.081592	0.0023220	0.0072292
GO:0008863	formate dehydrogenase (NAD+) activity	molecular_function	25.44807	22.35587	22.17642	NA	NA	NA	25.46355	18.59244	23.85371	20.30016	25.72806	18.51735	24.69012	21.08338	25.69053	16.89639	25.08835	21.47296	26.28459	19.68833	25.79686	20.52420	26.23668	25.20359	3.092205	0.0000266	0.0003880
GO:0004067	asparaginase activity	molecular_function	24.61922	21.51652	21.81286	NA	18.33977	19.66633	23.41328	19.99066	22.95452	20.94964	24.14038	22.23039	22.45801	20.23792	23.35429	16.71494	26.82331	21.92327	26.15231	20.13962	23.82537	15.82563	24.01837	23.80397	3.102706	0.0046639	0.0129353
GO:0015462	ATPase-coupled protein transmembrane transporter activity	molecular_function	23.04216	19.93311	NA	NA	NA	NA	22.88831	NA	24.29372	17.56517	22.86077	NA	22.54019	17.92395	22.50526	19.23924	21.92494	22.07157	NA	NA	22.76587	17.88682	23.25159	18.17014	3.109049	0.0000460	0.0004873
GO:0043546	molybdopterin cofactor binding	molecular_function	26.71611	23.60123	23.88869	17.84686	18.99855	18.97006	26.94399	22.71705	25.03683	24.46521	27.11660	22.91324	25.62911	22.22893	26.44709	23.30735	26.38818	23.52638	28.50183	22.62707	26.98884	23.33199	27.09214	25.76097	3.114880	0.0052895	0.0143911
GO:0033592	RNA strand annealing activity	molecular_function	21.32485	18.20276	17.62497	NA	NA	16.95442	20.27990	15.81102	20.33836	18.73714	20.70005	NA	19.61782	16.56889	19.70890	NA	22.11644	19.17560	23.28804	17.85465	21.87405	16.35505	20.48607	19.57673	3.122086	0.0007006	0.0027281
GO:0034057	RNA strand-exchange activity	molecular_function	21.32485	18.20276	17.62497	NA	NA	16.95442	20.27990	15.81102	20.33836	18.73714	20.70005	NA	19.61782	16.56889	19.70890	NA	22.11644	19.17560	23.28804	17.85465	21.87405	16.35505	20.48607	19.57673	3.122086	0.0007006	0.0027281
GO:0015846	polyamine transport	biological_process	24.61078	21.47369	22.10328	17.25982	21.73514	18.90082	24.38950	17.75950	24.40683	21.53448	25.08901	18.06749	24.34826	19.56273	23.74113	15.16255	23.68750	21.24479	26.01957	18.32097	25.43517	19.32447	24.91497	24.49069	3.137091	0.0000110	0.0002061
GO:0019808	polyamine binding	molecular_function	24.56125	21.42317	22.10328	17.25982	21.73514	18.90082	24.38950	17.75950	24.31793	21.40590	25.06940	18.06749	24.29427	19.56273	23.73331	15.16255	23.43488	21.13527	25.94123	18.32097	25.40496	19.26150	24.90885	24.45138	3.138081	0.0000101	0.0001976
GO:0046165	alcohol biosynthetic process	biological_process	26.36394	23.22337	20.06786	21.34467	21.92607	22.22670	27.30492	22.16507	26.56194	20.50511	26.95174	23.20537	26.17425	23.29893	26.76372	22.30042	27.16584	25.57737	21.32025	22.77398	26.55437	22.99346	26.69775	21.61745	3.140572	0.0076958	0.0195670
GO:0051289	protein homotetramerization	biological_process	24.46833	21.32708	21.71836	NA	21.22155	21.08923	23.90717	17.86729	23.87770	21.88370	25.27288	19.74928	23.36608	14.94809	23.75529	17.44008	26.57365	23.58450	24.47657	17.30533	23.73970	20.94819	23.88981	21.97208	3.141250	0.0002990	0.0014940
GO:0042954	lipoprotein transporter activity	molecular_function	21.40487	18.25176	NA	NA	NA	NA	21.04543	NA	19.63353	NA	22.63334	19.40201	18.24874	NA	20.05107	NA	22.12513	17.33605	20.68878	17.44407	21.23608	16.89417	22.35732	18.61786	3.153104	0.0016010	0.0053393
GO:0015423	maltose-transporting ATPase activity	molecular_function	22.42048	19.24658	19.30724	19.27832	NA	NA	23.27983	19.35023	22.94532	17.02196	21.50721	19.11796	21.26115	NA	22.67925	18.00297	23.23779	20.76648	NA	NA	21.89379	18.20140	NA	NA	3.173894	0.0003289	0.0015820
GO:0016782	transferase activity, transferring sulfur-containing groups	molecular_function	29.51288	26.33885	24.19743	25.26191	25.80214	25.87824	29.90739	25.76737	30.82852	25.51283	29.61398	26.07949	30.21102	26.57348	29.73877	25.39750	28.45798	28.24710	25.39673	25.16063	29.31223	26.49996	30.37777	25.85670	3.174022	0.0029028	0.0087084
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	molecular_function	22.21380	19.02228	20.80114	17.76499	18.57310	NA	22.43298	15.94075	20.57858	15.77894	22.86139	18.76659	21.38626	19.08058	20.69016	18.67512	23.99907	20.09394	22.77623	17.41959	22.34137	NA	21.38848	20.72798	3.191526	0.0001581	0.0009463
GO:0016869	intramolecular transferase activity, transferring amino groups	molecular_function	26.21586	23.02024	19.68440	NA	22.11602	20.04025	26.55375	22.07387	27.11127	22.66490	26.39541	21.07740	27.25577	22.81131	26.32029	23.15087	24.74099	24.88245	24.29715	22.04339	26.48698	22.34818	26.99165	23.68131	3.195618	0.0043977	0.0122971
GO:0045127	N-acetylglucosamine kinase activity	molecular_function	22.23086	19.00848	NA	NA	NA	NA	23.55170	14.12382	18.90654	16.75983	21.70462	NA	18.07688	NA	21.08264	NA	NA	NA	23.37010	19.86690	22.96679	16.83347	20.64103	20.45273	3.222383	0.0151685	0.0334330
GO:0034017	trans-2-decenoyl-acyl-carrier-protein isomerase activity	molecular_function	22.32246	19.07156	20.69664	NA	NA	NA	22.43298	15.94075	20.57858	15.77894	22.85464	18.35749	21.38007	18.49888	20.26786	NA	23.99907	20.09394	22.77623	17.41959	22.32366	NA	21.38848	20.72798	3.250908	0.0001529	0.0009212
GO:0097311	bacterial biofilm matrix	cellular_component	23.21768	19.96301	21.23461	NA	NA	NA	22.90808	17.04590	22.47147	20.17835	23.94545	16.46807	22.22545	NA	22.04145	NA	NA	NA	24.85054	16.47527	23.42376	NA	22.18245	21.78218	3.254673	0.0004864	0.0021022
GO:0033711	4-phosphoerythronate dehydrogenase activity	molecular_function	25.76366	22.50198	20.97064	18.90299	19.87037	21.16173	23.92331	20.91696	26.30736	21.89340	26.21140	20.43762	27.09718	22.80931	26.34048	21.23043	24.62580	24.71402	23.34495	21.36010	26.46202	23.35554	26.41481	22.08536	3.261684	0.0026887	0.0081743
GO:0045240	dihydrolipoyl dehydrogenase complex	cellular_component	23.83389	20.56018	20.81390	18.18876	23.05225	22.55868	23.42402	18.90938	22.17872	19.49498	23.78622	20.23052	22.05988	16.02682	22.43726	15.67416	25.10885	21.49638	25.40833	19.10920	23.99398	19.90475	23.93099	21.71570	3.273710	0.0000658	0.0005776
GO:0003727	single-stranded RNA binding	molecular_function	22.35754	19.08335	18.62497	NA	NA	17.95442	21.27990	16.81102	21.33836	19.73714	21.76630	NA	20.61782	17.56889	20.70890	15.84724	23.25732	20.30714	24.29585	18.85465	22.87405	17.35505	21.48607	20.57673	3.274194	0.0003433	0.0016226
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	molecular_function	24.37137	21.09257	NA	NA	18.21248	19.82180	24.08149	15.90302	25.98724	22.91433	23.64419	19.03557	26.05405	20.04857	22.44120	15.72481	22.81375	22.70010	19.07685	NA	23.45059	21.02387	24.55142	19.21801	3.278799	0.0100461	0.0242930
GO:0004609	phosphatidylserine decarboxylase activity	molecular_function	24.77611	21.48369	22.91000	16.94439	NA	NA	24.91372	21.54702	23.62339	22.21253	25.37989	19.34795	23.35690	19.65004	24.01946	17.39369	22.20536	19.75801	26.25832	17.45587	25.59065	19.35778	24.73149	24.09136	3.292425	0.0000359	0.0004308
GO:0008815	citrate (pro-3S)-lyase activity	molecular_function	25.78584	22.48588	22.74853	19.78811	25.58597	20.38242	25.71432	21.42863	26.42146	23.04840	26.30741	22.51295	25.77026	21.49054	26.48092	22.02021	24.56345	24.00862	22.46564	21.54853	25.41006	22.97991	26.89630	23.17037	3.299960	0.0000184	0.0002955
GO:0019146	arabinose-5-phosphate isomerase activity	molecular_function	20.64102	17.32692	NA	NA	NA	NA	20.06329	17.37034	20.91781	16.82329	20.34385	17.98228	20.14986	18.42349	18.39345	NA	19.44248	16.65972	16.75200	16.01411	21.35293	NA	22.33766	16.37897	3.314108	0.0009448	0.0034517
GO:0004053	arginase activity	molecular_function	22.74046	19.42272	NA	NA	18.56072	16.44855	22.31503	15.13451	23.55935	16.72880	22.79232	16.16036	22.13523	21.71982	22.75885	15.15424	21.47063	20.94277	NA	NA	23.71490	18.86727	23.17318	15.03579	3.317737	0.0001483	0.0008958
GO:0045239	tricarboxylic acid cycle enzyme complex	cellular_component	25.48727	22.16944	22.74820	18.59873	23.48866	22.93658	25.40148	20.59685	24.72267	22.37291	25.42589	21.52449	24.25999	20.80543	24.47288	20.96266	26.26369	22.83911	27.08377	20.69872	26.07828	20.83707	25.40610	24.13897	3.317826	0.0000073	0.0001584
GO:0008851	ethanolamine ammonia-lyase activity	molecular_function	25.35981	22.03329	23.03539	20.03067	19.37897	22.33708	26.18920	21.96214	24.84530	21.74852	25.94263	23.05369	22.97061	19.88989	25.22395	20.13814	26.39654	23.52508	24.26459	21.95405	24.79396	22.19302	26.68953	20.49222	3.326519	0.0007534	0.0028600
GO:0070689	L-threonine catabolic process to propionate	biological_process	24.49035	21.15444	NA	NA	NA	NA	23.32670	21.74218	21.49898	19.77211	23.39972	17.53467	23.12765	17.62044	22.00636	17.92861	26.80242	22.51346	NA	NA	NA	NA	23.25518	22.33956	3.335918	0.0076327	0.0194430
GO:0070403	NAD+ binding	molecular_function	24.42268	21.07461	19.47634	18.57028	NA	NA	24.06547	19.42960	26.03757	22.92400	23.78152	21.56131	26.06642	20.50747	22.45760	16.17524	22.81454	22.30760	19.07685	NA	23.48247	17.82329	24.71918	19.49806	3.348069	0.0057630	0.0154780
GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor	molecular_function	25.22595	21.87327	23.78072	21.18521	NA	NA	24.78864	17.15164	25.02180	22.23641	26.36522	19.60784	25.78883	19.29541	22.70508	14.63684	22.12937	14.83224	24.87906	18.57775	23.80802	19.64437	26.75933	24.75107	3.352686	0.0001129	0.0007546
GO:0072329	monocarboxylic acid catabolic process	biological_process	27.93798	24.58235	24.11197	23.62919	23.95982	24.04074	27.96963	24.39010	28.77616	23.95072	28.45183	24.33208	28.62204	23.78078	28.09725	23.21834	28.30805	26.63422	26.05044	23.77378	27.68559	24.41870	28.52545	24.36934	3.355621	0.0000487	0.0004999
GO:0052591	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity	molecular_function	25.16717	21.81077	22.94491	21.14273	21.21812	18.22033	23.71672	21.87230	25.21654	20.25967	25.69162	20.67160	25.40887	20.28262	24.41748	21.16507	26.89551	23.31618	25.54539	22.26988	25.16884	20.24812	24.13904	23.35210	3.356393	0.0000381	0.0004502
GO:0098809	nitrite reductase activity	molecular_function	25.08619	21.70621	23.78072	21.18521	18.87314	18.47267	24.78864	17.15164	25.02145	22.19962	26.36486	18.59637	25.78883	19.29541	22.67370	14.63684	22.13457	15.69133	24.83527	18.51347	23.81757	19.64437	26.75795	24.71892	3.379981	0.0002023	0.0011137
GO:0042279	nitrite reductase (cytochrome, ammonia-forming) activity	molecular_function	25.17721	21.79629	23.78072	21.18521	NA	NA	24.78264	17.15164	25.02145	22.19962	26.32699	18.51762	25.78831	19.27770	22.57797	14.63684	22.12937	14.83224	24.54344	17.46340	23.59897	18.92186	26.73804	24.70399	3.380922	0.0000781	0.0006205
GO:0008746	NAD(P)+ transhydrogenase activity	molecular_function	24.42710	21.03503	19.65299	NA	NA	NA	23.56144	17.99675	22.56851	19.96323	25.16138	17.98895	22.58411	18.86908	24.76515	14.28537	23.28762	19.68769	26.01579	20.25047	24.97863	19.90319	24.43463	23.76174	3.392073	0.0003041	0.0015111
GO:0030258	lipid modification	biological_process	27.96463	24.56977	23.74903	22.28401	23.54364	22.96874	27.94890	23.59050	28.72493	23.25860	28.43582	23.72619	28.60230	24.64382	28.06254	22.93181	28.81821	26.96947	25.01054	22.73346	27.63969	24.85576	28.52027	24.33118	3.394861	0.0001906	0.0010723
GO:0051538	3 iron, 4 sulfur cluster binding	molecular_function	23.93774	20.53717	19.75581	NA	NA	NA	23.14615	20.41611	23.01774	21.84272	24.93457	18.32099	24.48819	19.59508	22.14349	20.00164	22.92703	19.76506	25.43425	19.16236	24.22510	20.19700	23.08033	21.81338	3.400574	0.0001355	0.0008392
GO:0009678	hydrogen-translocating pyrophosphatase activity	molecular_function	25.29965	21.87941	NA	NA	NA	NA	24.88577	18.52493	25.90075	19.81505	25.16882	20.63706	25.55543	22.61470	24.50352	18.87485	24.23732	24.22817	NA	NA	25.52870	19.63444	25.78348	19.10662	3.420239	0.0000154	0.0002644
GO:1902653	secondary alcohol biosynthetic process	biological_process	26.14206	22.71757	19.36561	21.12678	21.92607	22.22670	27.28895	21.42068	26.54739	20.15098	26.73068	20.58691	26.11692	23.20690	26.76281	21.29518	25.71512	25.13998	20.94454	22.77398	26.54035	22.21684	26.50390	20.81835	3.424490	0.0042620	0.0120292
GO:0090329	regulation of DNA-dependent DNA replication	biological_process	22.98711	19.54254	NA	NA	NA	NA	22.51971	16.21643	NA	NA	23.82517	19.92617	NA	NA	22.05581	17.41711	23.39956	20.16794	22.65228	11.56131	22.89265	16.85271	22.84192	21.41632	3.444570	0.0014052	0.0047800
GO:0045333	cellular respiration	biological_process	26.92218	23.46952	24.11978	15.60709	24.08106	23.54382	26.51491	21.42875	25.42410	22.58683	27.80940	20.98372	25.76388	23.70437	26.48807	23.58694	27.59869	24.51378	28.35853	24.00108	27.25282	20.43692	26.93518	25.09589	3.452664	0.0002387	0.0012523
GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine	biological_process	23.30640	19.83647	20.15135	17.68694	22.54686	21.86457	22.93394	16.41172	21.74644	17.22735	23.41964	18.18344	21.65025	16.02682	21.98675	NA	24.13519	20.58282	25.10376	18.22113	23.12248	17.72707	23.63240	21.32909	3.469927	0.0000182	0.0002940
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	molecular_function	25.70341	22.22509	20.76681	20.99101	20.95521	20.79868	26.52078	21.75661	26.84717	22.53986	26.59103	22.69270	26.27161	23.36108	24.76679	20.99280	24.17574	23.07682	22.64330	21.06299	25.13901	21.64365	26.67437	22.61500	3.478318	0.0015982	0.0053393
GO:0008750	NAD(P)+ transhydrogenase (AB-specific) activity	molecular_function	24.16266	20.67912	19.52987	NA	NA	NA	23.32822	17.39842	22.33341	19.71634	24.92257	17.60138	22.05778	18.29643	24.67380	14.28537	22.25155	18.64426	25.76360	20.24413	24.72861	19.61158	24.14343	23.40182	3.483535	0.0002599	0.0013354
GO:0004615	phosphomannomutase activity	molecular_function	25.27382	21.76063	23.95326	20.56279	NA	NA	25.38533	16.15507	24.29083	22.24582	25.53859	21.44605	24.06797	18.44010	24.43789	20.55522	22.47570	23.42395	26.35262	19.60640	26.49990	19.14109	25.56398	23.46157	3.513188	0.0000493	0.0004999
GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity	molecular_function	21.96685	18.44758	18.76730	NA	NA	NA	22.26670	17.47480	21.58980	17.93061	22.55733	15.64987	20.68865	16.36010	21.16572	16.79802	19.77394	19.98526	23.31144	17.56431	21.89190	17.75830	22.72431	20.04606	3.519267	0.0000295	0.0003993
GO:0009326	formate dehydrogenase complex	cellular_component	22.65563	19.12933	NA	NA	NA	NA	22.58000	NA	21.41651	17.90608	22.61230	NA	21.56976	20.05004	22.06407	NA	23.58831	19.55346	23.28899	16.25209	22.95016	NA	22.39687	19.39328	3.526300	0.0000321	0.0004044
GO:0050215	propanediol dehydratase activity	molecular_function	25.31859	21.78718	21.03918	17.98620	16.22022	19.96974	25.54974	22.37595	27.23379	23.20358	22.91086	19.41061	26.30411	20.64945	23.33021	21.17728	26.45529	23.69721	23.79671	20.97237	24.83218	20.34932	23.67450	20.70807	3.531410	0.0151789	0.0334330
GO:0043545	molybdopterin cofactor metabolic process	biological_process	26.17376	22.64125	22.03003	16.12512	19.00515	20.42949	26.57984	21.08303	24.17217	22.33853	26.63060	21.98101	25.08541	24.68327	25.17145	20.04725	24.34764	21.99134	28.40723	22.14450	26.32928	22.72392	26.05525	23.84370	3.532509	0.0043048	0.0121249
GO:0031241	periplasmic side of cell outer membrane	cellular_component	22.94598	19.41127	19.58127	NA	NA	NA	22.66731	13.57772	21.58313	20.93241	23.91683	16.37860	23.04428	15.45608	22.95516	14.15827	21.62651	18.91391	24.02494	16.16196	23.15297	18.44226	22.92479	21.60503	3.534716	0.0000642	0.0005730
GO:0006530	asparagine catabolic process	biological_process	23.89933	20.36060	20.70368	NA	17.71125	18.23425	21.70406	18.98874	21.49268	19.14036	22.49226	18.84223	21.29222	17.80540	22.53411	NA	26.65388	21.59788	24.81221	17.16669	23.15893	NA	22.21458	22.34950	3.538727	0.0069463	0.0179809
GO:0006325	chromatin organization	biological_process	24.41547	20.85818	19.69711	NA	NA	20.98854	25.49247	20.85779	23.42899	17.71086	24.39142	19.46242	22.73602	NA	24.62986	20.90768	21.32469	22.51755	23.79273	17.64501	25.32860	18.43325	25.58017	21.80308	3.557294	0.0005895	0.0024096
GO:0006531	aspartate metabolic process	biological_process	27.07980	23.51810	24.19780	18.54159	NA	NA	26.35028	20.56775	26.02775	24.07509	27.13749	21.98648	25.59013	21.89800	25.07485	20.41843	28.94505	25.09041	27.60533	20.92643	27.15044	21.75068	NA	25.56995	3.561702	0.0001019	0.0007193
GO:0008814	citrate CoA-transferase activity	molecular_function	25.07267	21.49404	21.86847	19.24372	24.24591	19.03392	25.10881	20.66142	25.63709	22.61419	25.46922	21.22096	25.22057	20.10929	25.74556	20.94714	24.10486	23.40640	21.30028	19.75557	24.99297	21.65264	26.25808	21.16809	3.578631	0.0000113	0.0002101
GO:0009735	response to cytokinin	biological_process	23.02469	19.43806	20.77311	NA	NA	21.24305	21.40046	16.92624	21.68905	18.23418	22.32953	16.18929	21.37642	18.67994	NA	17.74882	24.92003	21.37805	23.23846	15.52031	23.72801	17.91585	22.34589	18.79055	3.586634	0.0000440	0.0004759
GO:0071824	protein-DNA complex subunit organization	biological_process	22.53419	18.93496	NA	NA	NA	NA	22.64080	17.68057	19.21675	18.40230	22.85176	18.10848	NA	NA	NA	NA	NA	NA	23.60503	18.08905	22.60104	18.30358	21.31219	20.57822	3.599233	0.0010130	0.0036518
GO:0015807	L-amino acid transport	biological_process	23.85990	20.25882	NA	NA	NA	17.89059	22.54830	16.37348	25.02337	16.33038	23.78617	NA	22.40178	NA	24.60664	NA	23.20278	22.42998	17.52910	NA	23.25834	17.69502	24.90213	NA	3.601074	0.0029351	0.0087955
GO:0004370	glycerol kinase activity	molecular_function	25.88299	22.24512	22.47773	21.87616	21.50666	21.61168	25.81456	20.63673	26.41748	20.45033	26.59125	22.54339	25.47696	21.64444	23.03005	21.27331	27.31548	23.62300	27.11358	21.39045	24.37157	20.14937	24.97229	23.91419	3.637870	0.0001313	0.0008193
GO:0008693	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	molecular_function	22.35528	18.71336	20.23129	NA	NA	NA	22.43298	15.94075	20.57858	15.77894	22.82464	16.83806	19.75972	16.65901	NA	NA	23.99907	20.09394	22.77623	17.41959	22.32366	NA	21.14267	20.39050	3.641918	0.0001680	0.0009819
GO:0005310	dicarboxylic acid transmembrane transporter activity	molecular_function	24.85164	21.19498	17.64627	NA	NA	NA	23.51039	19.41645	25.87813	20.92124	24.92310	16.37762	24.32101	18.99958	25.50861	17.85657	25.00931	23.28956	22.10082	18.03107	24.99712	18.75165	25.75588	22.76166	3.656663	0.0010379	0.0036971
GO:0044815	DNA packaging complex	cellular_component	21.89162	18.23389	NA	NA	NA	NA	21.64080	NA	18.21675	17.40230	21.88330	17.90493	NA	NA	NA	NA	22.43606	17.86947	22.39931	17.08905	22.16282	19.03717	NA	18.97191	3.657738	0.0009363	0.0034251
GO:0042737	drug catabolic process	biological_process	28.95397	25.27404	25.05411	22.85623	26.98056	26.38449	29.23782	24.70249	29.84870	23.04003	28.80879	24.46946	29.71075	24.59835	28.98915	22.99725	28.76673	27.65024	27.10554	23.70455	29.48519	23.57720	29.42060	24.34796	3.679931	0.0000026	0.0000843
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	molecular_function	23.18555	19.50370	19.83285	18.01240	20.32188	19.37179	22.89964	17.82182	21.64300	17.36544	23.52754	17.88570	20.65104	18.67787	22.07015	15.34923	25.15740	21.34234	24.04218	17.85143	23.04717	19.80638	23.26623	21.14454	3.681849	0.0000392	0.0004588
GO:0047702	beta-lysine 5,6-aminomutase activity	molecular_function	25.30113	21.61505	NA	NA	NA	NA	25.32951	16.82694	25.48162	18.37123	25.38036	16.82255	26.51543	21.42913	24.98088	22.11966	22.85931	23.73308	20.73902	NA	25.64380	21.77058	25.53346	17.76766	3.686084	0.0004921	0.0021162
GO:0008968	D-sedoheptulose 7-phosphate isomerase activity	molecular_function	23.09516	19.40698	19.13313	NA	NA	NA	23.21130	18.48891	22.61944	19.11438	23.49310	18.11425	21.49369	16.92467	23.07559	14.41176	22.59190	20.16753	23.80819	16.99230	23.87237	17.40458	23.62185	21.70112	3.688174	0.0000344	0.0004186
GO:2001061	D-glycero-D-manno-heptose 7-phosphate biosynthetic process	biological_process	23.09516	19.40698	19.13313	NA	NA	NA	23.21130	18.48891	22.61944	19.11438	23.49310	18.11425	21.49369	16.92467	23.07559	14.41176	22.59190	20.16753	23.80819	16.99230	23.87237	17.40458	23.62185	21.70112	3.688174	0.0000344	0.0004186
GO:0008691	3-hydroxybutyryl-CoA dehydrogenase activity	molecular_function	24.45971	20.76662	NA	NA	NA	NA	24.02762	14.95354	25.98644	22.91433	23.64419	19.03557	25.91296	19.50093	22.14316	15.72481	22.80622	22.18454	19.07685	NA	23.34821	15.80885	24.55142	17.43493	3.693082	0.0010184	0.0036648
GO:0009793	embryo development ending in seed dormancy	biological_process	22.01127	18.29527	19.71979	NA	NA	NA	21.02122	NA	21.14453	17.99335	21.90199	13.19187	21.79001	18.30092	22.47524	NA	23.39058	19.70277	22.37277	14.30129	21.66695	18.76864	21.86854	18.36833	3.715996	0.0000940	0.0006866
GO:0035672	oligopeptide transmembrane transport	biological_process	22.73102	18.99738	NA	NA	NA	NA	21.29359	17.93753	NA	NA	21.84860	18.39413	23.61398	19.56933	22.31273	NA	NA	20.36059	19.22905	NA	22.85276	18.25921	23.94486	16.70004	3.733646	0.0009710	0.0035142
GO:0009346	citrate lyase complex	cellular_component	25.82106	22.08149	22.76058	19.78811	25.68424	20.38242	25.90186	20.69821	26.43183	22.68965	26.20443	22.01681	25.77915	21.43512	26.49345	21.13622	24.59636	24.04758	21.80685	20.07359	25.37470	22.03228	27.01816	22.50781	3.739566	0.0000071	0.0001554
GO:0061024	membrane organization	biological_process	25.80959	22.06230	NA	NA	22.85282	20.43454	25.91561	19.32457	24.69478	21.40044	26.17898	20.65191	24.68949	20.86964	25.36160	NA	25.84699	22.69666	26.40761	21.03284	26.59995	NA	26.46848	24.07616	3.747288	0.0000043	0.0001180
GO:0102040	fumarate reductase (menaquinone)	molecular_function	26.19096	22.42511	24.20560	22.15759	23.52125	22.94795	25.53128	19.05429	25.02160	22.40025	27.48106	21.94232	24.99761	19.83991	25.45957	20.26950	25.85682	22.52704	27.83672	21.40748	26.25834	18.72360	26.27148	24.71854	3.765854	0.0000037	0.0001056
GO:0043165	Gram-negative-bacterium-type cell outer membrane assembly	biological_process	25.23121	21.45778	22.88131	21.03403	22.55031	19.83934	25.31929	19.17329	23.53727	21.18001	25.70687	18.75439	23.39739	20.71135	25.08048	18.76067	25.27888	22.20950	26.23037	20.63449	26.34571	20.60791	25.82228	23.83382	3.773435	0.0000017	0.0000620
GO:0016156	fumarate reductase (NADH) activity	molecular_function	21.68595	17.89752	21.91090	16.15968	21.94415	14.62156	NA	NA	NA	NA	20.42353	NA	21.68626	19.60443	NA	NA	21.93554	18.98019	21.82141	16.20173	22.09446	16.79765	20.95764	16.71022	3.788434	0.0000081	0.0001699
GO:0006857	oligopeptide transport	biological_process	24.39731	20.59590	19.70670	17.81576	21.13680	20.52341	22.91992	19.55829	26.15111	19.15810	23.64563	20.29562	25.19895	21.15429	23.94990	NA	23.00631	22.15170	21.67309	21.32897	24.65196	20.39917	25.61721	18.79903	3.801408	0.0002773	0.0014062
GO:0030151	molybdenum ion binding	molecular_function	26.17428	22.34894	22.29214	18.63200	NA	NA	26.46482	20.09551	24.19362	23.33367	26.49372	22.24713	23.92483	16.59655	25.32842	21.38013	24.66616	22.20092	28.25908	20.48027	26.18842	21.20496	25.91867	24.56465	3.825346	0.0001474	0.0008947
GO:0004129	cytochrome-c oxidase activity	molecular_function	23.99221	20.16374	20.25151	NA	NA	NA	22.79598	19.40700	20.99360	18.19523	23.09483	18.81882	NA	NA	24.61020	NA	NA	NA	24.79070	17.59651	25.12815	NA	24.43070	22.00782	3.828474	0.0021469	0.0067149
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	biological_process	26.13675	22.29762	22.03003	16.12512	19.00515	20.42949	26.56135	21.08303	24.10504	22.33853	26.59416	21.98101	24.68009	23.70381	25.16415	20.02250	24.23220	21.95740	28.39972	21.65586	26.28606	22.69560	26.02452	23.80562	3.839126	0.0029424	0.0088077
GO:0044571	[2Fe-2S] cluster assembly	biological_process	22.39658	18.55696	NA	NA	NA	NA	22.20314	16.26072	19.63162	17.50749	22.26746	16.21475	20.22619	NA	23.78407	NA	23.17877	19.82064	22.30584	18.16052	22.32732	16.86313	21.69207	19.96085	3.839616	0.0000502	0.0004999
GO:0004612	phosphoenolpyruvate carboxykinase (ATP) activity	molecular_function	27.21825	23.35273	25.72863	19.74071	23.77163	18.36701	27.80431	22.75392	26.94473	24.26307	27.11652	22.53598	26.90525	21.83178	26.43371	20.13360	27.18725	23.63554	28.42141	22.05283	27.92956	21.68774	27.20059	25.78174	3.865519	0.0000027	0.0000852
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	biological_process	26.04028	22.14774	20.86596	19.98749	20.60128	19.29981	27.28745	20.15392	NA	NA	26.76208	21.33753	26.12672	20.02513	26.76160	18.93319	25.69880	24.95156	20.16161	18.50192	26.53558	20.88214	NA	NA	3.892539	0.0035173	0.0102465
GO:0003333	amino acid transmembrane transport	biological_process	23.87703	19.98068	NA	NA	NA	NA	22.54830	16.37348	25.02337	16.33038	23.79117	NA	22.40178	NA	24.62498	16.33156	23.20192	22.42827	17.52910	NA	23.39107	17.69502	24.91580	16.63646	3.896344	0.0007088	0.0027338
GO:0042445	hormone metabolic process	biological_process	22.24149	18.34147	NA	NA	NA	NA	22.75459	16.87944	23.40852	16.14423	22.89748	NA	19.76840	13.03593	22.39559	18.37861	22.22596	20.68886	17.67662	NA	21.78341	14.35845	21.72568	16.12605	3.900029	0.0003185	0.0015488
GO:0046930	pore complex	cellular_component	27.35632	23.43294	25.29959	18.10527	16.77311	22.91746	27.44667	16.48200	26.30443	23.81050	27.30443	21.07727	25.84150	21.45674	27.45543	20.36988	28.66569	25.69650	27.68171	23.71058	28.05534	19.13298	27.91363	24.65599	3.923377	0.0021079	0.0066159
GO:0030288	outer membrane-bounded periplasmic space	cellular_component	28.58354	24.62584	24.95043	24.02426	24.45577	22.71275	29.12774	23.54898	29.43178	23.49734	28.79299	24.29672	28.79341	25.03884	28.37604	22.46441	28.90008	26.57454	27.78081	22.46227	29.12426	25.06681	28.78707	25.06091	3.957704	0.0000053	0.0001307
GO:0006835	dicarboxylic acid transport	biological_process	24.54694	20.57436	NA	NA	NA	NA	23.05001	17.29439	25.80804	18.01471	24.17496	NA	24.11606	18.81266	24.87224	NA	24.17496	22.94377	19.88678	NA	24.08751	18.10449	25.50440	17.01320	3.972580	0.0001686	0.0009833
GO:0008202	steroid metabolic process	biological_process	28.00387	24.03107	NA	NA	NA	NA	28.87391	21.56628	28.13072	21.03638	28.31458	19.30803	27.68970	21.56000	28.34915	22.13807	27.28152	26.55736	21.32955	NA	28.12850	24.25439	28.08690	22.18222	3.972809	0.0003485	0.0016398
GO:0015081	sodium ion transmembrane transporter activity	molecular_function	25.93532	21.96126	NA	NA	NA	NA	25.35982	21.84004	27.04158	18.42649	25.76221	22.34791	25.92944	20.34580	26.37011	18.19030	24.51280	24.28350	20.58595	19.03334	25.49945	21.91300	26.78704	19.54829	3.974054	0.0001464	0.0008922
GO:0015288	porin activity	molecular_function	27.48432	23.50131	25.43612	18.45039	16.77311	22.91746	27.67472	17.47878	26.38582	23.85257	27.51560	21.15366	25.89684	21.48070	27.60105	20.38270	28.66611	25.70692	27.79521	23.71830	28.26084	19.63867	28.05826	24.88523	3.983018	0.0019746	0.0062625
GO:0045262	plasma membrane proton-transporting ATP synthase complex, catalytic core F(1)	cellular_component	24.07395	20.07472	22.41686	NA	NA	NA	24.03505	NA	22.66568	20.75712	24.63989	14.71685	23.22900	18.21947	23.96492	14.88856	22.53724	19.27460	25.55795	16.59166	23.75551	14.15649	24.58452	22.50412	3.999224	0.0000212	0.0003319
GO:0047124	L-erythro-3,5-diaminohexanoate dehydrogenase activity	molecular_function	26.67838	22.67517	NA	NA	NA	NA	27.03212	17.37611	27.47749	20.53570	26.43460	17.85965	27.13396	20.81699	26.65013	17.01991	25.01183	25.50324	22.19632	NA	26.82563	19.77348	27.07722	20.21242	4.003212	0.0000309	0.0004042
GO:0008816	citryl-CoA lyase activity	molecular_function	24.51609	20.50149	21.64397	18.11841	25.01996	19.66290	24.66016	15.38656	25.19245	18.39515	24.87987	20.77893	24.13991	20.70075	25.18776	18.11096	22.80408	22.56889	20.05104	17.73591	23.26990	19.92057	25.73022	21.78258	4.014600	0.0000229	0.0003426
GO:0006113	fermentation	biological_process	28.86221	24.82725	23.41159	NA	26.50636	NA	29.12772	21.88155	29.77594	23.45263	28.80857	22.22423	29.64839	23.17821	28.96103	22.41181	27.94842	27.43226	27.73733	23.23501	29.49213	23.73975	29.34779	24.71864	4.034962	0.0000176	0.0002881
GO:0044242	cellular lipid catabolic process	biological_process	27.74777	23.67312	22.31549	21.50327	23.22554	21.76967	27.93923	23.12507	28.70215	22.43186	28.40204	23.51788	28.59667	22.95906	28.04758	21.88127	26.97362	26.24249	24.42470	22.06159	27.58579	23.52874	28.48701	22.48750	4.074652	0.0000937	0.0006863
GO:0009062	fatty acid catabolic process	biological_process	27.74319	23.61179	22.31549	21.50327	23.11783	21.64841	27.93175	23.12507	28.70042	22.43186	28.39782	22.60316	28.58782	22.95802	28.04758	21.88127	26.96273	26.24232	24.40693	22.00498	27.58207	23.52725	28.48701	22.48750	4.131402	0.0000776	0.0006205
GO:0047111	formate dehydrogenase (cytochrome-c-553) activity	molecular_function	23.56545	19.39007	20.07116	NA	NA	NA	24.19457	17.93881	23.02395	19.19071	23.56338	16.50135	21.96792	17.78539	23.16929	16.90864	22.83939	19.01428	24.84059	18.48684	24.25335	18.84596	23.49600	21.74882	4.175386	0.0000020	0.0000684
GO:0050485	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor	molecular_function	26.49292	22.29093	28.02057	17.51191	22.40196	15.98057	24.92465	22.90240	27.25464	21.89145	21.11630	NA	28.76102	22.52541	22.26500	17.76856	23.84795	24.62027	19.59713	16.86072	26.17895	17.83827	23.83525	22.72435	4.201993	0.0042030	0.0119245
GO:0098803	respiratory chain complex	cellular_component	25.66644	21.46333	22.52175	NA	NA	NA	24.25487	15.07137	24.31421	21.14138	26.40394	17.47151	23.75944	18.29641	24.71157	15.02865	26.40147	23.11024	27.20442	20.75883	25.91635	17.92534	25.53364	23.52372	4.203105	0.0000498	0.0004999
GO:0016125	sterol metabolic process	biological_process	27.41637	23.17769	NA	NA	NA	NA	28.28750	19.88701	27.54576	18.70725	27.72856	18.78052	27.10152	19.37730	27.76074	20.23417	26.69655	25.95127	20.74459	NA	27.53900	22.61238	27.49533	19.69805	4.238681	0.0000912	0.0006727
GO:0045284	plasma membrane fumarate reductase complex	cellular_component	25.62278	21.36019	22.52175	NA	NA	NA	24.25487	15.07137	24.31421	21.14138	26.40394	17.47151	23.75944	18.29641	24.71157	15.02865	26.12396	22.79932	27.20442	20.75883	25.91106	17.92534	25.52973	23.51892	4.262592	0.0000413	0.0004667
GO:0042128	nitrate assimilation	biological_process	26.61430	22.33776	24.00414	21.22457	21.56332	20.41954	26.86561	19.63311	25.46317	22.61964	27.33664	20.68406	26.14417	19.57856	25.32377	16.44708	25.27643	21.83764	28.45380	19.88925	26.34675	20.12872	27.27402	25.20864	4.276539	0.0000084	0.0001747
GO:0009350	ethanolamine ammonia-lyase complex	cellular_component	24.78182	20.49919	18.37930	NA	NA	NA	25.53660	17.83462	24.08665	17.22618	25.38816	18.87582	21.41789	14.98755	24.22461	15.72501	26.22591	22.99291	19.99271	18.11860	24.31691	21.53304	25.70966	19.45235	4.282625	0.0006747	0.0026771
GO:0003985	acetyl-CoA C-acetyltransferase activity	molecular_function	27.02267	22.73842	20.13519	NA	21.07290	19.54744	27.24399	19.72976	27.91683	18.95227	27.83754	20.45635	28.21620	22.47108	27.16037	16.55273	26.27078	25.72429	22.77424	16.51674	25.77320	20.02405	27.81976	21.89107	4.284245	0.0003074	0.0015164
GO:1905039	carboxylic acid transmembrane transport	biological_process	24.49760	20.20021	NA	NA	NA	NA	23.05001	17.29439	25.80804	18.01471	24.12163	NA	24.11606	18.81266	24.88752	16.33156	23.47735	22.73650	18.36876	NA	24.14575	18.10449	25.50750	17.56663	4.297392	0.0002212	0.0011835
GO:0047545	2-hydroxyglutarate dehydrogenase activity	molecular_function	25.88466	21.54266	NA	NA	NA	NA	25.72346	15.47459	26.90295	16.28720	24.00367	18.17953	27.03311	19.74179	25.02501	14.94078	24.25585	24.33646	20.93190	NA	25.94652	18.62993	26.59961	20.53426	4.342002	0.0000739	0.0006069
GO:0005343	organic acid:sodium symporter activity	molecular_function	25.79746	21.44548	NA	NA	NA	NA	24.82489	17.51884	26.91279	18.42649	25.59105	NA	25.85574	20.01333	26.25355	17.23937	24.50867	24.23447	19.23282	18.46923	25.40575	19.21906	26.69442	18.54501	4.351978	0.0000916	0.0006727
GO:0047826	D-lysine 5,6-aminomutase activity	molecular_function	25.13698	20.77789	NA	NA	NA	NA	25.05151	16.95901	26.41827	19.60453	24.65063	18.50053	25.72063	20.46207	25.19158	19.35478	22.96472	23.51489	20.40235	15.09234	24.47492	16.46542	25.70699	19.33013	4.359090	0.0000425	0.0004726
GO:0004733	pyridoxamine-phosphate oxidase activity	molecular_function	25.78266	21.39179	NA	NA	NA	NA	26.42786	16.17117	26.60521	19.95566	26.46599	22.40183	26.11881	20.77266	24.64445	18.60542	23.90029	22.89892	21.70308	20.41614	24.83993	21.08502	26.36218	22.10043	4.390870	0.0000656	0.0005776
GO:0018730	glutaconate CoA-transferase activity	molecular_function	27.83682	23.43340	19.12411	NA	NA	NA	28.17792	18.38318	28.79582	22.21272	28.04257	20.41168	28.40317	22.87947	27.96921	19.21250	26.63144	26.31364	22.92992	18.91584	27.67056	19.57835	28.60117	21.16342	4.403414	0.0005040	0.0021560
GO:0044433	cytoplasmic vesicle part	cellular_component	24.81622	20.38901	NA	20.02884	NA	NA	25.74121	20.29477	20.90084	20.69186	25.18820	21.16286	25.26026	20.44195	20.91350	19.72974	19.48784	20.73865	NA	NA	NA	NA	26.01079	19.05236	4.427213	0.0092578	0.0227100
GO:0019665	anaerobic amino acid catabolic process	biological_process	28.93007	24.48496	NA	NA	NA	NA	29.03987	21.49754	29.73607	23.12802	28.45892	21.45199	29.61913	23.01343	28.85535	21.72645	27.35480	27.34982	25.08887	21.65317	29.26589	22.07884	29.21930	22.42108	4.445110	0.0000016	0.0000594
GO:0008108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity	molecular_function	24.43064	19.96312	NA	NA	18.79496	NA	25.23358	16.06538	22.93369	19.30134	24.03848	18.30675	22.67162	21.07691	23.64949	16.09713	20.64019	21.18879	25.68767	19.31564	25.65337	17.19484	24.96212	21.35657	4.467517	0.0003043	0.0015111
GO:0003859	3-hydroxybutyryl-CoA dehydratase activity	molecular_function	24.42894	19.96019	NA	NA	NA	NA	24.04713	17.10721	24.29373	15.89056	24.77137	15.39973	26.04068	20.31473	24.31256	16.05047	22.04518	22.10246	NA	NA	22.56219	NA	23.71487	NA	4.468745	0.0001048	0.0007304
GO:0003995	acyl-CoA dehydrogenase activity	molecular_function	27.76290	23.26927	21.39691	NA	21.77097	20.73976	27.61328	21.77356	28.92240	22.40193	27.88866	21.83883	29.30116	23.31086	27.89586	20.58762	26.82355	26.09127	23.13439	17.75107	27.68621	20.72906	28.06703	19.98697	4.493625	0.0003514	0.0016465
GO:0015655	alanine:sodium symporter activity	molecular_function	24.74142	20.24618	NA	NA	NA	NA	24.05689	14.13569	25.79302	17.51661	24.36535	17.52687	25.56502	18.82156	24.78504	15.73703	22.55656	23.02730	17.85953	NA	24.53949	17.50397	25.45168	18.20619	4.495237	0.0001677	0.0009819
GO:0015175	neutral amino acid transmembrane transporter activity	molecular_function	24.74312	20.24618	NA	NA	NA	NA	24.05689	14.13569	25.79302	17.51661	24.36535	17.52687	25.56502	18.82156	24.78504	15.73703	22.62459	23.02730	17.85953	NA	24.53949	17.50397	25.45168	18.20619	4.496938	0.0001642	0.0009724
GO:0006083	acetate metabolic process	biological_process	28.90840	24.40571	NA	NA	NA	NA	29.03379	20.43069	29.73293	22.44378	28.45884	21.12314	29.57266	22.84270	28.84523	21.24253	27.28105	27.35642	24.58840	20.82438	29.24062	21.31236	29.20865	22.04646	4.502687	0.0000025	0.0000823
GO:0019477	L-lysine catabolic process	biological_process	28.71291	24.18977	20.15135	17.68694	22.75096	22.11439	29.17281	20.05788	29.81306	21.82975	28.53681	21.32329	29.60967	22.71360	28.92754	20.13134	27.21712	27.43429	25.86150	19.09885	29.31655	21.48189	29.33774	22.36989	4.523146	0.0001080	0.0007467
GO:0008410	CoA-transferase activity	molecular_function	29.46906	24.92678	22.65015	20.00422	24.24591	19.03392	29.87867	22.77512	30.81430	24.14691	29.56489	22.62456	30.18329	24.74747	29.71307	22.14407	28.34804	27.93162	24.35653	20.86088	29.25379	22.54275	30.35794	24.26788	4.542282	0.0001676	0.0009819
GO:0005283	amino acid:sodium symporter activity	molecular_function	25.36398	20.80617	NA	NA	NA	NA	24.49140	16.65089	26.45892	18.04212	25.10463	17.52687	25.71769	19.53716	25.69860	16.67551	23.84030	23.75362	18.70376	17.53932	25.03669	18.60265	26.20292	18.38552	4.557813	0.0000338	0.0004174
GO:0019475	L-lysine catabolic process to acetate	biological_process	28.89046	24.31718	NA	NA	NA	NA	29.03135	19.81662	29.73116	21.75053	28.45211	21.12314	29.56531	22.67672	28.83590	20.07941	26.85627	27.32386	24.49828	17.81760	29.23856	21.31236	29.20607	21.38682	4.573283	0.0000052	0.0001299
GO:0015370	solute:sodium symporter activity	molecular_function	25.88188	21.29452	NA	NA	NA	NA	25.22836	17.62165	26.96313	18.42649	25.69366	17.70858	25.92879	20.01333	26.34570	17.36693	24.50867	24.23447	19.23282	18.46923	25.48540	19.21906	26.73208	18.75471	4.587363	0.0000292	0.0003985
GO:0004085	butyryl-CoA dehydrogenase activity	molecular_function	27.82566	23.22512	21.39691	NA	21.77097	20.73976	27.95829	19.93474	28.88585	21.66669	28.11724	21.79011	29.21983	23.01888	27.90274	20.29883	26.67569	26.19710	22.94528	17.68378	27.80637	19.84321	28.32476	18.84269	4.600545	0.0001735	0.0010077
GO:0035673	oligopeptide transmembrane transporter activity	molecular_function	22.84899	18.23101	NA	NA	19.14473	15.90135	21.28259	16.21070	24.55485	17.47697	21.87179	NA	23.59165	17.31393	22.30006	NA	21.14118	20.52314	17.66044	NA	22.85030	16.13801	23.93594	16.49325	4.617988	0.0002024	0.0011137
GO:0015558	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity	molecular_function	23.14836	18.50322	NA	NA	NA	NA	21.28259	16.21070	24.55485	17.47697	21.83335	NA	23.59165	17.31393	22.30006	NA	20.95286	20.35845	NA	NA	22.85000	NA	23.93594	16.49325	4.645141	0.0000643	0.0005730
GO:1902604	p-aminobenzoyl-glutamate transmembrane transport	biological_process	23.14836	18.50322	NA	NA	NA	NA	21.28259	16.21070	24.55485	17.47697	21.83335	NA	23.59165	17.31393	22.30006	NA	20.95286	20.35845	NA	NA	22.85000	NA	23.93594	16.49325	4.645141	0.0000643	0.0005730
GO:0008720	D-lactate dehydrogenase activity	molecular_function	24.60434	19.93910	19.09592	NA	NA	NA	24.05163	20.69650	26.48327	19.79937	23.65560	14.98112	25.47119	19.74829	23.46966	19.73781	23.76187	21.98613	19.40003	14.04414	24.98682	17.79922	24.50376	17.92512	4.665236	0.0004873	0.0021022
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	biological_process	27.42581	22.70646	20.11143	NA	NA	NA	27.50443	20.85119	28.46181	18.56695	27.96797	19.34152	27.83956	20.33201	27.55191	18.25606	26.21636	25.70660	23.99901	15.71588	27.45460	20.22768	27.97371	19.90262	4.719348	0.0000397	0.0004607
GO:0072349	modified amino acid transmembrane transporter activity	molecular_function	23.15263	18.41753	NA	NA	NA	17.89059	21.28259	16.21070	24.56204	17.47697	21.87048	NA	23.59165	17.31393	22.30006	NA	20.95286	20.35845	NA	NA	22.85000	NA	23.93594	16.49325	4.735103	0.0000191	0.0003018
GO:0004352	glutamate dehydrogenase (NAD+) activity	molecular_function	27.52613	22.70312	20.50113	NA	22.63600	21.33008	28.14932	19.64101	28.47351	18.06662	27.70694	20.79882	28.22820	19.82644	27.62118	14.96620	27.41441	25.75143	23.16943	18.17662	27.20725	22.13396	28.44108	18.54791	4.823015	0.0000571	0.0005399
GO:0047371	butyrate-acetoacetate CoA-transferase activity	molecular_function	26.96525	22.13330	NA	NA	NA	NA	26.94923	17.88450	28.51157	19.80057	26.10656	18.63308	27.36544	21.85845	26.82420	17.09416	25.52360	24.85191	20.09045	NA	26.01728	18.55977	27.46841	19.26744	4.831952	0.0000874	0.0006518
GO:0030699	glycine reductase activity	molecular_function	24.85415	20.00061	22.39913	16.07032	NA	NA	23.50792	19.33586	25.45930	19.13085	17.79891	NA	27.32304	21.52124	20.53436	16.76856	21.20160	21.91005	NA	NA	24.95040	12.85825	22.21820	14.12966	4.853535	0.0038946	0.0111077
GO:0042938	dipeptide transport	biological_process	24.06737	19.12977	NA	NA	NA	NA	22.34467	17.38032	25.57177	18.61891	23.14220	16.12374	24.59165	18.31393	23.37835	NA	22.14672	21.49413	20.77883	14.65249	24.13129	18.27803	24.96508	18.29316	4.937609	0.0000103	0.0001991
GO:0050371	tyrosine phenol-lyase activity	molecular_function	28.26571	23.26617	23.74157	NA	NA	NA	28.37101	20.07507	27.74279	19.80648	28.29356	19.78799	28.70688	22.13533	28.41435	18.40095	24.37090	23.48305	28.91284	21.32548	28.57075	20.59040	29.13788	25.99729	4.999541	0.0000051	0.0001299
GO:0030700	glycine reductase complex	cellular_component	23.98444	18.95029	21.12940	NA	NA	NA	22.79955	18.38021	NA	NA	NA	NA	26.20513	18.58145	20.08748	16.39932	20.98268	20.69272	NA	NA	24.45699	NA	21.52011	14.12966	5.034149	0.0051215	0.0139957
GO:0006020	inositol metabolic process	biological_process	24.09188	18.91012	NA	NA	NA	NA	24.14879	17.68807	21.50600	17.18571	24.45133	20.42639	NA	NA	21.94610	19.39129	NA	NA	25.23179	17.92634	24.20377	17.92921	NA	NA	5.181766	0.0000660	0.0005776
GO:0019310	inositol catabolic process	biological_process	24.07821	18.87709	NA	NA	NA	NA	24.12474	17.68807	21.42987	16.89015	24.44326	20.42639	NA	NA	21.94610	19.39129	NA	NA	25.22363	17.84699	24.18868	17.77083	NA	NA	5.201123	0.0000778	0.0006205
GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances	molecular_function	22.85016	17.60542	NA	NA	NA	NA	22.91202	16.90804	20.87671	15.88938	23.27063	19.11044	NA	NA	20.87285	NA	NA	NA	23.95859	17.02717	22.78091	16.79660	NA	NA	5.244747	0.0000598	0.0005514
GO:0047569	3-oxoadipate CoA-transferase activity	molecular_function	24.87228	19.60980	NA	NA	NA	NA	24.97946	16.75437	26.45231	18.95115	23.78130	17.14960	24.88571	19.29527	22.99189	14.87262	23.44763	22.16899	NA	NA	24.35231	17.09491	25.02649	16.73475	5.262482	0.0000026	0.0000836
GO:0008923	lysine decarboxylase activity	molecular_function	26.13204	20.72907	21.69061	NA	NA	NA	20.57249	NA	26.68931	20.87035	24.83204	19.24762	NA	NA	22.29173	15.68197	28.45754	22.82640	25.06165	17.50869	25.12273	17.69765	NA	NA	5.402972	0.0025611	0.0078469
GO:0050112	inositol 2-dehydrogenase activity	molecular_function	23.37362	17.86305	NA	NA	NA	NA	22.92319	NA	22.59480	15.90561	23.92071	19.78934	NA	NA	21.50716	16.02025	NA	NA	24.07031	16.03743	23.78416	16.47041	NA	NA	5.510569	0.0000269	0.0003880
GO:0009034	tryptophanase activity	molecular_function	27.36374	21.42933	NA	NA	NA	NA	27.33805	18.70783	27.99940	19.31410	27.91372	19.39130	28.90436	21.52695	25.99411	17.38321	24.94888	23.92004	25.46843	NA	26.89174	20.08928	26.43814	19.29630	5.934413	0.0000003	0.0000273
GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity	molecular_function	24.05541	17.56137	NA	NA	NA	NA	24.77803	19.44676	21.01723	15.28747	22.89343	14.71250	NA	NA	19.76823	NA	NA	NA	25.31859	16.23086	24.46655	16.73070	NA	NA	6.494043	0.0005388	0.0022497
GO:0018826	methionine gamma-lyase activity	molecular_function	26.59095	19.94483	NA	NA	NA	NA	27.55352	18.21894	27.86947	19.55929	26.07222	18.43756	27.23440	19.32933	25.96194	19.58609	23.84484	22.24722	NA	NA	25.03246	17.57051	24.47129	14.45452	6.646123	0.0000018	0.0000649
GO:0047982	homocysteine desulfhydrase activity	molecular_function	25.56156	18.31466	NA	NA	NA	NA	26.02980	15.68420	27.25355	18.65321	25.06006	17.36714	26.50060	18.23801	23.32939	NA	22.05136	20.13084	NA	NA	24.04006	17.45161	22.41634	13.51889	7.246900	0.0000104	0.0002001

2.2 Principal Components

# principal components, function
full_func_descript <- read.delim('mqome_outputs/func_full_descript_out.tab')

plt_principal_components(full_func_descript, 6:27, ns_ws_colors)

2.3 Heatmap

# heatmap, function
plt_heatmap(full_func_descript, 6:27, ns_ws_colors)

3 Function - GO Slim

3.1 Volcano Slim

func_slim <- read.delim('mqome_outputs/func_slim_test_out.tab') %>%
    mutate(de = abs(log2fc_NS_over_WS) > 1 & corrected_p < 0.05)
plt_volcano(func_slim)

## Warning: Removed 4 rows containing missing values (geom_point).

# ggsave("plots/func_slim_volcano.png",dpi = 700, width = 6, height = 5, units = "in")

3.1.1 Differentially expressed GO terms (Slim)

knitr::kable(filter(func_slim, de) %>%
                 arrange(log2fc_NS_over_WS) %>% select(-starts_with("Intensity"), -de)) %>%
    kable_styling()

id	name	namespace	NS_mean	WS_mean	X730NS	X730WS	X733NS	X733WS	X734NS	X734WS	X737NS	X737WS	X769NS	X769WS	X781NS	X781WS	X795NS	X795WS	X852NS	X852WS	X861NS	X861WS	X866NS	X866WS	X867NS	X867WS	log2fc_NS_over_WS	p	corrected_p
GO:0006914	autophagy	biological_process	19.55573	22.14121	20.60747	22.62067	NA	NA	NA	NA	17.25824	20.65072	NA	NA	17.84309	22.37619	17.53330	21.90478	20.67495	22.43298	NA	NA	NA	NA	NA	NA	-2.585481	0.0051556	0.0248408
GO:0008134	transcription factor binding	molecular_function	25.48547	27.32927	24.91928	26.58995	23.68376	26.73467	25.43367	27.59433	26.61840	27.95546	25.94078	26.24057	25.86835	27.37518	25.36744	27.52515	24.55253	28.24431	24.57674	27.05614	24.51953	25.97618	26.26378	27.64081	-1.843802	0.0000176	0.0004240
GO:0005856	cytoskeleton	cellular_component	23.63117	24.95369	24.43131	24.73131	25.30946	25.12051	21.10501	24.93579	21.12632	24.44430	23.19259	25.20339	24.16124	25.24173	21.69023	23.77543	24.03829	24.83880	23.65743	25.08369	22.02995	25.43150	22.87523	25.04844	-1.322521	0.0005531	0.0045097
GO:0005618	cell wall	cellular_component	28.80908	30.05417	29.23939	29.58806	30.11123	30.26496	27.82320	29.81322	27.76547	29.84484	28.58316	29.52678	29.33688	30.51711	28.06201	30.47491	28.37651	30.17123	29.12747	29.99807	27.80235	29.95705	28.51979	30.07649	-1.245095	0.0000159	0.0004240
GO:0040007	growth	biological_process	25.09980	26.30769	24.49477	23.68895	25.39983	25.62545	25.03395	25.61637	24.60949	26.00785	25.61460	26.18500	25.72829	27.43957	24.26167	26.78606	24.78765	25.76356	25.97157	27.17624	24.41941	25.82797	24.47976	26.37879	-1.207887	0.0066393	0.0293237
GO:0030234	enzyme regulator activity	molecular_function	25.76403	26.96163	24.75849	25.84789	23.97024	27.21353	25.36724	27.27910	26.92196	26.35704	26.27715	25.57477	26.28334	27.49461	25.62306	27.71077	25.36617	26.84626	25.39366	26.10506	25.49253	27.77075	25.89397	26.45873	-1.197601	0.0016203	0.0095416
GO:0002376	immune system process	biological_process	24.46651	25.47755	23.04182	23.85622	26.76799	26.67862	21.65968	24.15147	21.46621	23.02197	23.45079	24.80146	25.58801	26.69685	20.38584	24.31924	22.10615	23.95893	25.58573	26.68980	20.96247	25.09745	22.43984	25.41581	-1.011043	0.0168398	0.0495837
GO:0019899	enzyme binding	molecular_function	24.78138	25.78831	25.41985	25.56779	24.85770	25.32164	24.50218	25.88973	24.53945	26.23361	24.77631	25.45824	24.71411	25.52048	24.67513	26.14965	25.55094	26.07854	24.42785	25.11676	23.63848	25.86829	24.62799	26.00906	-1.006933	0.0000200	0.0004240
GO:0006091	generation of precursor metabolites and energy	biological_process	29.93065	28.77259	28.44531	25.64594	27.92019	26.80231	29.86387	28.85363	30.28738	29.51071	30.37635	27.92040	30.48164	28.97340	30.15482	28.99307	29.61558	28.69908	30.27878	28.78962	29.89914	27.81585	30.07998	30.12798	1.158062	0.0064459	0.0293237
GO:0005654	nucleoplasm	cellular_component	20.95687	19.07677	NA	NA	NA	NA	20.91544	18.82605	21.75230	15.63548	21.05747	18.45874	19.61008	17.41342	19.05275	19.13597	21.49154	20.70673	NA	NA	20.69971	NA	21.30717	19.02275	1.880104	0.0043230	0.0218211
GO:0031012	extracellular matrix	cellular_component	23.21971	20.51822	21.23461	NA	NA	NA	22.90808	17.04590	22.47147	20.17835	23.94545	19.88883	22.24232	17.85400	22.04145	21.43981	NA	NA	24.85054	16.47527	23.43215	21.48846	22.18245	21.78218	2.701490	0.0009643	0.0067890

3.2 Principal Components (Slim)

# principal components, function
slim_func_descript <- read.delim('mqome_outputs/func_slim_descript_out.tab')
plt_principal_components(slim_func_descript, 6:27, ns_ws_colors)

3.3 Heatmap (Slim)

plt_heatmap(slim_func_descript, 6:27, ns_ws_colors)

# dev.off()